Relationship between endothelial nitric oxide synthase gene polymorphisms and the risk of myocardial infarction in the Algerian population

Introduction: Endothelial nitric oxide synthase (eNOS), the enzyme in charge of nitric oxide production, plays a crucial role in vascular biology. However, the impact of single nucleotide polymorphisms (SNPs) affecting the gene encoding for eNOS (eNOS) on coronary artery diseases remains under debate and no data were available at present in populations originating from Mahghreb.Aim of the Study: Our purpose was to evaluate the association between the eNOS -786T/C and +894G/T SNPs and (i) the risk of myocardial infarction (MI) and (ii) variations in systolic (SBP) and diastolic (DBP) blood pressure values.Patients and Methods: Concerning MI, the SNPs were characterised in a casecontrol study (70 cases vs 68 controls) based on the male population originating from Oran, Algeria.Results: The associations with blood pressure values were assessed in anenlarged control group including 115 male subjects. Since the -786T/CSNP could not be associated to MI, the genotype distribution of the+894G/T genotypes signifi cantly differed between MI cases and controls(p=0.025). The risk of MI (odds ratio) associated to the +894G/T SNP wasestimated to 1.2 (95%CI=[1.03;1.32]). The haplotype analysis confi rmedthis association and the absence of impact of the -786T/C SNP. On the other hand, no consistent association was shown between the two SNPs and SBP or DBP.Conclusion: As observed in other populations, the eNOS +894G/T SNPwas associated with MI in the Algerian population but the mechanismunderlying the effect could not be related to variations in blood pressure.Keywords: Endothelial nitric oxide synthase, myocardial infarction, blood pressure, genetic epidemiology

Impacts of climate change on plant diseases – opinions and trends

There has been a remarkable scientific output on the topic of how climate change is likely to affect plant diseases in the coming decades. This review addresses the need for review of this burgeoning literature by summarizing opinions of previous reviews and trends in recent studies on the impacts of climate change on plant health. Sudden Oak Death is used as an introductory case study: Californian forests could become even more susceptible to this emerging plant disease, if spring precipitations will be accompanied by warmer temperatures, although climate shifts may also affect the current synchronicity between host cambium activity and pathogen colonization rate. A summary of observed and predicted climate changes, as well as of direct effects of climate change on pathosystems, is provided. Prediction and management of climate change effects on plant health are complicated by indirect effects and the interactions with global change drivers. Uncertainty in models of plant disease development under climate change calls for a diversity of management strategies, from more participatory approaches to interdisciplinary science. Involvement of stakeholders and scientists from outside plant pathology shows the importance of trade-offs, for example in the land-sharing vs. sparing debate. Further research is needed on climate change and plant health in mountain, boreal, Mediterranean and tropical regions, with multiple climate change factors and scenarios (including our responses to it, e.g. the assisted migration of plants), in relation to endophytes, viruses and mycorrhiza, using long-term and large-scale datasets and considering various plant disease control methods

Pruning effects on canopy growth and photosynthesis in young peach trees (Prunus persica L. Bratsch)

We consider the stability properties of spatial and temporal periodic orbits of one-dimensional coupled-map lattices. The stability matrices for them are of the block-circulant form. This helps us to reduce the problem of stability of spatially periodic orbits to the smaller orbits corresponding to the building blocks of spatial periodicity, enabling us to obtain the conditions for stability in terms of those for smaller orbits

Trait-based approach for agroecology: contribution of service crop root traits to explain soil aggregate stability in vineyards

International audienceAims The aim of this study was to explore the impact of soil management strategies and the contribution of root traits of plant communities and soil organic carbon (SOC) in explaining soil aggregate stability in vineyards.Methods: We measured topsoil aggregate stability, soil properties and root traits of 38 plant communities in an experimental vineyard, previously subjected to different soil management strategies. Then we investigated statistical relations between aggregate stability, root traits and SOC and estimated root trait and SOC contributions to gain insight into aggregate stability.Results: Soil management strategies strongly affected soil aggregate stability, with a negative effect of tillage, even after several years of service crop cover. Among the investigated parameters, soil organic carbon was found to contribute the most to aggregate stability. Root mean diameter and root mass density showed positive correlations with aggregate stability, while specific root length showed a negative correlation with aggregate stability.Conclusions: Soil aggregate stability is the result of complex interactions between soil management strategies, soil properties and plant root traits. Service crops improve aggregate stability, and a trait-based approach could help to identify service crop ideotypes and expand the pool of species of interest for providing services in agroecosystems in relation with the soil physical quality