Trajectories of Antidepressant Medication before and after the Onset of Unemployment by Subsequent Employment Experience

Peer reviewe

Citral hydrogenation over Pt loaded micro- and mesoporous supports : the interplay between steric limitations and acidity

The effect of pore morphology and acidity on the selectivity in the hydrogenation of citral was investigated on a series of bifunctional catalysts: Pt-H-SAPO-5, Pt-H-Y zeolite, and Pt-H-MCM-41. The reaction was studied in a batch reactor at 70oC with 10 bar total pressure. The highest selectivity to the unsaturated alcohols of 57% was obtained on the Pt-H-SAPO-5 catalyst at a conversion of 46%. The interplay among a monodimensional pore channel of the H-SAPO-5 support, weak Br?nsted acidity of this silicoaluminophosphate, and large platinum nanoparticles contributed to a high selectivity. The corresponding turn over frequency was 0.036 s-1. Pt-H-MCM-41 showed the highest selectivity to menthol as by product, while Pt-H-Y zeolite demonstrated the highest dehydration rate

Identification of the VAl-ON defect complex in AlN single crystals

In this Rapid Communication, we report positron annihilation results on in-grown and proton irradiation-induced vacancies and their decoration in aluminium nitride (AlN) single crystals. By combining positron lifetime and coincidence Doppler measurements with ab initio calculations, we identify in-grown VAl−ON complexes in the concentration range 10 exp 18 cm exp −3 as the dominant form of VAl in the AlN single crystals, while isolated VAl were introduced by irradiation. Further, we identify the UV absorption feature at around 360 nm that involves VAl.Peer reviewe

Why the Realist-Instrumentalist Debate about Rational Choice Rests on a Mistake

Within the social sciences, much controversy exists about which status should be ascribed to the rationality assumption that forms the core of rational choice theories. Whilst realists argue that the rationality assumption is an empirical claim which describes real processes that cause individual action, instrumentalists maintain that it amounts to nothing more than an analytically set axiom or ‘as if’ hypothesis which helps in the generation of accurate predictions. In this paper, I argue that this realist-instrumentalist debate about rational choice theory can be overcome once it is realised that the rationality assumption is neither an empirical description nor an ‘as if’ hypothesis, but a normative claim

Kinetic regularities, catalyst deactivation and reactivation

Funding text 1 The research is funded from Ministry of Education and Science of the Russian Federation Program No. 075–03–2021–287/6 (Russia). Funding text 2 XPS measurements were carried out at the Central laboratories of Tomsk Polytechnic University (Analytical Center). HRTEM was carried out at the Innovation centre for Nanomaterials and Nanotechnologies of Tomsk Polytechnic University. The ICP-OES analysis was carried out using the core facilities of “Physics and Chemical methods of analysis” of Tomsk Polytechnic University. Fundação para a Ciência e a Tecnologia for Scientific Employment Stimulus Institutional Call (CEECINST/00102/2018), UIDB/50006/2020 and UIDP/50006/2020 (LAQV), UIDB/00100/2020 and UIDP/00100/2020 (Centro de Química Estrutural).Betulin, being a pentacyclic triterpene alcohol and an extractive from birch bark, along with its oxo-derivatives, has a broad range of physiological properties of interest for synthesis of pharmaceuticals. Instead of oxidizing betulin with strong and toxic oxidizing agents the present study shows a possibility of using liquid-phase oxidation of betulin with air over supported Ag NPs catalysts as an alternative method for synthesis of its oxo-derivatives. Based on catalytic studies, high resolution transmission electron microscopy, X-ray photoelectron spectroscopy and ultraviolet-visible diffuse reflectance spectroscopy, the evolution of the surface of nanosilver catalysts during the catalysis was demonstrated, as well as under the impact of reactant gas composition. The kinetic regularities and causes of deactivation of supported Ag NPs catalysts were revealed. An approach to the regeneration of silver catalysts was proposed. Kinetic analysis with numerical data fitting was performed resulting in an adequate description of the concentration dependencies.publishersversionpublishe

Economics Imperialism in Law and Economics

Non peer reviewe

The Role of Parvalbumin-positive Interneurons in Auditory Steady-State Response Deficits in Schizophrenia

© The Author(s) 2019. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.Despite an increasing body of evidence demonstrating subcellular alterations in parvalbumin-positive (PV+) interneurons in schizophrenia, their functional consequences remain elusive. Since PV+ interneurons are involved in the generation of fast cortical rhythms, these changes have been hypothesized to contribute to well-established alterations of beta and gamma range oscillations in patients suffering from schizophrenia. However, the precise role of these alterations and the role of different subtypes of PV+ interneurons is still unclear. Here we used a computational model of auditory steady-state response (ASSR) deficits in schizophrenia. We investigated the differential effects of decelerated synaptic dynamics, caused by subcellular alterations at two subtypes of PV+ interneurons: basket cells and chandelier cells. Our simulations suggest that subcellular alterations at basket cell synapses rather than chandelier cell synapses are the main contributor to these deficits. Particularly, basket cells might serve as target for innovative therapeutic interventions aiming at reversing the oscillatory deficits.Peer reviewe

Diffusion Measurements of Hydrocarbons in Zeolites with Pulse-Field Gradient Nuclear Magnetic Resonance Spectroscopy

Pulse field gradient NMR technique was used to determine self-diffusivity of heptane and pentadecane at room temperature for microporous catalysts, used both as powders and shaped with a binder extrudates. The results showed that diffusivities increased with increasing specific surface area, micro- and mesopore volume of the studied catalysts. The presence of Bindzil binder together with H-Beta-25 decreased hydrocarbon diffusivities. Self-diffusivities of heptane and pentadecane were smaller for extrudates than for the powder catalysts. The detailed information about mass transfer limitations is needed to further process optimization since effective diffusivity is directly correlated with self-diffusion coefficients. The estimates of the ratio of porosity and tortuosity were also determined. The diffusion measurements with relatively long observation times Delta (20 up to 1000 ms) and catalysts fully immersed in pentadecane revealed that a small portion of sites exhibits very small diffusivities in H-Beta-25-Bindzil extrudates, which is correlated with a low ratio of mesopore to micropore volumes of this material