Detección de palabras cortadas al inicio y fin de línea en textos manuscritos

[ES] En este trabajo se describe el proceso de extracción de muestras con unas características definidas a partir de imágenes, las cuales son páginas escaneadas de un libro manuscrito, mediante visión artificial. Tras ello se aplicarán varios algoritmos de aprendizaje automático y diferentes técnicas aplicables a las muestras para detectar cuándo una palabra al final o al principio de una línea del texto es partida o no, es decir, si continúa en la siguiente línea o es continuación de la línea previa o por el contrario está entera.[EN] This project describes the extraction process of samples with defined features from images, which are scanned pages of a manuscript book through artificial vision. After that, a few machine learning algorithms and different techniques will be applied on the samples to detect when a word at the end or at the beginning of a line is splitted or not, that is, if the words continues on the next line or is a continuation of the previous line or is not and the word is not splitted.Gras Más, V. (2020). Detección de palabras cortadas al inicio y fin de línea en textos manuscritos. http://hdl.handle.net/10251/149003TFG

Diseño de una tolva y de un extrusor para alimentar una impresora 3D a partir de pellet

Treball Final de Grau en Enginyeria Mecànica. Codi: EM1047. Curs acadèmic: 2020/2021Actualmente se generan más de 300 millones de toneladas de residuos plásticos (Greenpeace, 2021) cada año, lo cual supone una grave amenaza para el medioambiente en general y para los océanos en particular. En consecuencia, urge no solo reducir la cantidad de plástico que se pone en circulación, sino también encontrar formas eficaces de reutilizar el ya existente. En este proyecto se diseñará una alternativa viable para la reutilización de dichos plásticos con el fin de darles una segunda vida útil y reducir los residuos que, de otra manera, se tratarían de formas menos sostenibles. El objeto de este proyecto es el diseño de una extrusora de pellet, un nuevo tipo de impresora que hace uso de residuos de plástico para la generación de filamento que posteriormente será extruido

Current and birth weights exert independent influences on nocturnal pressure-natriuresis relationships in normotensive children

The objective was to study the impact of birth weight on the relationship between ambulatory blood pressure and urinary sodium excretion in children and adolescents. The study included 134 healthy children (61 boys), all Caucasians, who were born at term after a normotensive pregnancy. For each subject, a 24-hour ambulatory blood pressure monitoring and a complete urine collection were simultaneously performed according to the protocols designed. Average ambulatory blood pressure (BP) and the urinary excretion rates for sodium, potassium, and creatinine were calculated separately for 24-hour, awake, and sleep periods defined by a mini-diary. The excretion rate of sodium during sleep time was positively correlated with ambulatory systolic BP; such a positive relationship was not found for waking hours. Consequently, the impact of birth weight on the relationship between blood pressure and the urinary sodium excretion rate was analyzed during sleeping hours. Stepwise multiple regression analysis shows that although current weight was the strongest predictor for the sodium excretion rate during sleep (P3.500 kg) of birth weight (P<.02). Differences in sodium excretion rates, adjusted for current weight, between the two extreme tertiles of birth weight became significant at the highest systolic BP (P<.04). The children who had the lowest birth weight tended to excrete less sodium during sleep. The results of the present study show a blunted pressure natriuresis curve in children and adolescents with the lowest birth weight. Whether this abnormal renal sodium handling may be present as an initial or as an intermediate mechanism leading to higher BP values must be assessed in additional studies.Lurbe Ferrer, Maria Desamparados, [email protected] ; Redon Mas, Josep, [email protected]

Birth weight influences blood pressure values and variability in children and adolescents

The objective of the present study was to assess the relationships between birth weight and the values and variability of ambulatory blood pressure. Six hundred thirty healthy children (369 girls) age 4 to 18 years (mean, 9.9 years) born at term after a normotensive pregnancy were included. The subjects were divided into 5 groups according to birth weight. For each subject, a 24-hour ambulatory blood pressure monitoring was performed according to the protocol designed. Average and variability (estimated as the standard deviation) of ambulatory blood pressure and heart rate were calculated separately for 24-hour, daytime, and nighttime periods. When values were adjusted for gender, current age, weight, and height, children with the lowest birth weights had the highest ambulatory blood pressure values and variability, whereas no differences in heart rate were observed. Multiple regression analysis showed that although current weight was the strongest predictor for 24-hour systolic blood pressure (P<0.001), there was also an independent and significant inverse relationship for birth weight (P<0.002) after controlling for gender, current age, and height. Likewise, birth weight was independently and inversely correlated with 24-hour systolic blood pressure variability (P<0.03). In conclusion, children who had lower birth weights tended to have not only the highest blood pressure values but also the highest blood pressure variability, independent of the increases in ambulatory blood pressure values. Knowing that high blood pressure variability is at least partially independent of blood pressure values, the importance of this variability on further blood pressure rises and/or on vascular damage later in life needs to be assessed in future studies.Lurbe Ferrer, Maria Desamparados, [email protected] ; Redon Mas, Josep, [email protected]

The harmful effect of removing the extracellular vitrification medium during embryo cryopreservation using a nylon mesh device in rabbit

[EN] During the last decades, many techniques have been developed to reduce sample volume and improve cooling and warming rates during embryo vitrification. The vast majority are based on the "minimum drop size" concept, in which the vitrification solution around embryos is reduced by aspiration, leaving a tiny part of volume surrounding embryos. However, novel cryodevices were aimed to remove the entire vitrification solution. This study was designed to compare the "minimum drop size" technique using Cryotop (R) with the nylon mesh as cryodevice on rabbit morula embryos. The outcomes assessed were the in vitro development rates (experiment 1) and the offspring rates at birth (experiment 2). Embryos were vitrified in a two-step procedure; equilibrium (10% EG + 10% Me2SO) for 2 min and vitrification (20% EG + 20% Me2SO) for 1 min. In experiment 1, embryos (n = 323) were warmed and subsequently in vitro cultured for 48 h to assess the embryo developmental capability to reach the hatching-hatched blastocyst stage. In experiment 2, embryos were transferred using the laparoscopic technique (n = 369) to assess the offspring rate at birth. In this context, rates of in vitro embryo development were similar between vitrified groups (0.73 +/- 0.042% and 0.66 +/- 0.047% for Cryotop (R) and nylon mesh device, respectively), but lower than in the fresh group (0.97 +/- 0.016%, p 3.0.co;2-pNakashima, A., Ino, N., Kusumi, M., Ohgi, S., Ito, M., Horikawa, T., … Saito, H. (2010). Optimization of a novel nylon mesh container for human embryo ultrarapid vitrification. Fertility and Sterility, 93(7), 2405-2410. doi:10.1016/j.fertnstert.2009.01.063Rall, W. F., & Fahy, G. M. (1985). Ice-free cryopreservation of mouse embryos at −196 °C by vitrification. Nature, 313(6003), 573-575. doi:10.1038/313573a0Saragusty, J., & Arav, A. (2011). Current progress in oocyte and embryo cryopreservation by slow freezing and vitrification. REPRODUCTION, 141(1), 1-19. doi:10.1530/rep-10-0236Sparks, A. (2015). Human Embryo Cryopreservation—Methods, Timing, and other Considerations for Optimizing an Embryo Cryopreservation Program. Seminars in Reproductive Medicine, 33(02), 128-144. doi:10.1055/s-0035-1546826Techakumphu, M., Wintenberger-Torrès, S., Sevellec, C., & Ménézo, Y. (1987). Survival of rabbit embryos after culture or culture/freezing. Animal Reproduction Science, 13(3), 221-228. doi:10.1016/0378-4320(87)90111-4Vicente, J. S., Viudes-de-Castro, M. P., Cedano-Castro, J. I., & Marco-Jiménez, F. (2018). Cryosurvival of rabbit embryos obtained after superovulation with corifollitropin alfa with or without LH. Animal Reproduction Science, 192, 321-327. doi:10.1016/j.anireprosci.2018.03.034Viudes De Castro, M. P., Cortell, C., & Vicente, J. S. (2010). Dextran vitrification media prevents mucin coat and zona pellucida damage in rabbit embryo. Theriogenology, 74(9), 1623-1628. doi:10.1016/j.theriogenology.2010.06.034Yamanaka, T., Goto, T., Hirabayashi, M., & Hochi, S. (2017). Nylon Mesh Device for Vitrification of Large Quantities of Rat Pancreatic Islets. Biopreservation and Biobanking, 15(5), 457-462. doi:10.1089/bio.2017.0044Zhang, X., Liu, J., & Huang, G. (2015). Efficiency of an automatic dehydrated carrier for the vitrification of human embryos derived from three pronuclei fertilized zygotes. Reproductive BioMedicine Online, 30(2), 144-149. doi:10.1016/j.rbmo.2014.10.01

Digital Competence of Secondary School Teachers: Analysis of the State of the Art

Verónica Más García – Universidad de Valencia - 0000-0002-8615-9949Vicente Gabarda Méndez – Universidad de Valencia - 0000-0001-6159-5173José Peirats Chacón – Universidad de Valencia - 0000-0002-6580-2712Recepción: 13.07.2022 | Aceptado: 18.07.2022Correspondencia a través de ORCID: Verónica Más García - 0000-0002-8615-9949La formación docente en la adquisición de Competencias Digitales (CD) es una pieza clave para su puesta en práctica y pedagógica en las aulas. Los docentes deben estar formados digitalmente teniendo en cuenta las áreas y competencias que el Marco Común de CD Docente (INTEF,2017) establece. El planteamiento del artículo se basa en realizar una revisión sistemática de la literatura científica para conocer que CD tiene el profesorado de Educación Secundaria en activo y los que cursan su Formación Inicial. Se analiza la producción científica en dos bases de datos Dialnet y Web of Science entre 2016 a 2021. Tras aplicar los criterios de exclusión e inclusión, se analizaron 25 artículos. Los resultados muestran que en los últimos años hay una preocupación manifiesta por esta temática atendiendo al volumen de propuestas publicadas. Asimismo, podemos constatar que, de manera general el profesorado tiene un nivel de competencia intermedia y que varía en función de variables como la especialidad que se imparte, la edad o el género del docente. Es reseñable, asimismo, que hay carencias generalizadas en las áreas de creación de contenidos digitales, resolución de problemas y seguridad digital, habiendo aún mucho trabajo por hacer en esta área.Abstract: Teacher training in the acquisition of Digital Competences (DC) is a key element for its practical and pedagogical implementation in the classroom. Teachers must be digitally trained taking into account the areas and competences that the Common Framework for Teacher CD (INTEF,2017) establishes. The approach of the article is based on carrying out a systematic review of the scientific literature to know what CD has the active Secondary Education teachers and those who are in their Initial Training. The scientific production is analyzed in two databases Dialnet and Web of Science from 2016 to 2021. After applying exclusion and inclusion criteria, 25 bibliographic articles were analyzed. The results show that in recent years there has been a clear concern for this subject in terms of the volume of proposals published. We can also see that, in general, the teaching staff have an intermediate level of competence, which varies according to variables such as the speciality taught, the age or gender of the teacher. It is also noteworthy that there are generalised deficiencies in the areas of digital content creation, problem solving and digital security, and that there is still much work to be done in this area.Universidad de Valenci

Libro de Actas del Primer Congreso Internacional de Análisis de Rendimiento Deportivo y Coaching

Este libro es una compliación de las Comunicaciones y Ponencias presentadas en el I Congreso Internacional de Análisis de Rendimiento Deportivo y Coaching, celebrado en la Facultad de Ciencias de la Actividad Física y el Deporte de la Universidad de Valencia entre el 25 y 27 de Marzo de 2015. Organizado por la Universidad de Valencia y la Asociación Valenciana de Análisis de Rendimiento Deportivo y Coaching.This book is a compilation of Communications and lectures presented at the Firsth International Conference on Performance Analysis and Coaching in Sport, performed in the Faculty of Physical Activity and Sport Sciences of the University of Valencia, 25-27th of March. Organized by the University of Valencia and The Valencian Association of Perfomance Analysis and Coaching in Sport

Birth weight impacts on wave reflections in children and adolescents

The objective of the present study was to assess central aortic pressure and wave reflection in children and adolescents at different birth weights. Two hundred nineteen healthy children (126 girls), from 7 to 18 years of age (mean, 11.3 years) and born at term after a normotensive pregnancy, were included. The subjects were divided according to birth weight: 3.5 kg. Pressure waveforms were recorded from the radial artery of the wrist, and the waveform data were then processed by the SphygmoCor radial/aortic transform software module to produce the estimated aortic pressure waveform. Augmentation index, an estimate of the pulse wave reflection, was significantly higher in children with the lowest birth weights compared with the other birth weight groups. In a multiple regression analysis, short stature, low heart rate, female gender, and lower birth weight had independent significant inverse correlations to the augmentation index when adjusted for diastolic blood pressure (R^2=0.21). In summary, the results showed a relatively aged phenotype of large-vessel function in the children with the lowest birth weights. These early alterations may be amplified throughout life and may contribute to the increased cardiovascular risk associated with low birth weight.Lurbe Ferrer, Maria Desamparados, [email protected] ; Redon Mas, Josep, [email protected]

Gender differences related to the presence of atrial fibrillation in older hypertensive patients.

AIM: To determine whether there are gender differences in the epidemiological profile of atrial fibrillation(AF) and to characterise the clinical, biochemical, and therapeutic factors associated with AF. METHODS: Each investigator (primary care physicians or physicians based in hospital units for hypertension treatment) recruited the first 3 patients with an ageof ≥ 65 years and a clinical diagnosis of hypertension(ambulatory blood pressure monitoring and an electrocardiogram,were performed) on the first working day of the week for 5 wk and identified those individuals with atrial fibrillation. A binary logistic regression was performed, including all of the variables that were significant in the univariate analysis, to establish the variables that were associated with the presence of arrhythmia.CONCLUSION: In patients with hypertension over 65 years of age, there are relevant gender differences in the factors associated with AF

A single injection of corifollitropin alfa supplemented with human chorionic gonadotropin increases follicular recruitment and transferable embryos in the rabbit

[EN] Contents Superovulation protocols are designed to achieve maximum embryo yields. Nevertheless, ovarian response control and the quality of obtained embryos are still a challenge. On the other hand, to save the superovulated embryos until their subsequent use, it is usual to cryopreserve them, so it is also crucial to assess their cryotolerance. The aim of this study was to compare the efficacy of a single injection of corifollitropin alfa (FSH-CTP) alone or supplemented with human chorionic gonadotropin (hCG) and to determine the impact of this stimulation on in vitro and in vivo development of fresh or devitrified embryos. Our outcomes showed that ovulation rate and recovered embryos were significantly increased when hCG was used. In vitro development of fresh and devitrified embryos and survival at birth were not significantly affected by superstimulation treatment. Results of this study suggest that a single injection of long-acting FSH-CTP supplemented with hCG can be effectively used in rabbits to elicit an increase in ovulation rate and number of recovered embryos. Furthermore, we demonstrated that hCG supplementation had no negative effects in embryo cryosurvival and development, showing similar survival rate at birth than FSH-CTP alone group.This research was supported by the Spanish Research project funded by Ministerio de Economía, Industria y Competitividad (MICINN) AGL2017¿85162¿C2¿1¿R and Generalitat Valenciana research pro¿ gram (Prometeo II 2014/036). X Garcia¿Dominguez was supported by a research grant from MICINN (BES¿2015¿072429).Viudes-De-Castro, MP.; Marco-Jiménez, F.; Más-Pellicer, A.; Garcia-Dominguez, X.; Talaván, AM.; Vicente Antón, JS. (2019). A single injection of corifollitropin alfa supplemented with human chorionic gonadotropin increases follicular recruitment and transferable embryos in the rabbit. Reproduction in Domestic Animals. 54(4):696-701. https://doi.org/10.1111/rda.13411S696701544Acevedo, B., Sanchez, M., Gomez, J. L., Cuadros, J., Ricciarelli, E., & Hernández, E. R. (2004). Luteinizing hormone supplementation increases pregnancy rates in gonadotropin-releasing hormone antagonist donor cycles. Fertility and Sterility, 82(2), 343-347. doi:10.1016/j.fertnstert.2004.03.020Besenfelder, U., & Brem, G. (1993). Laparoscopic embryo transfer in rabbits. Reproduction, 99(1), 53-56. doi:10.1530/jrf.0.0990053Boostanfar, R., Shapiro, B., Levy, M., Rosenwaks, Z., Witjes, H., Stegmann, B. J., … Yeko, T. (2015). Large, comparative, randomized double-blind trial confirming noninferiority of pregnancy rates for corifollitropin alfa compared with recombinant follicle-stimulating hormone in a gonadotropin-releasing hormone antagonist controlled ovarian stimulation protocol in older patients undergoing in vitro fertilization. Fertility and Sterility, 104(1), 94-103.e1. doi:10.1016/j.fertnstert.2015.04.018Campbell, R. K. (2005). Molecular Pharmacology of Gonadotropins. Endocrine, 26(3), 291-296. doi:10.1385/endo:26:3:291Carvalho, P. D., Hackbart, K. S., Bender, R. W., Baez, G. M., Dresch, A. R., Guenther, J. N., … Fricke, P. M. (2014). Use of a single injection of long-acting recombinant bovine FSH to superovulate Holstein heifers: A preliminary study. Theriogenology, 82(3), 481-489. doi:10.1016/j.theriogenology.2014.05.011Chappel, S. C., & Howles, C. (1991). REVIEW. Human Reproduction, 6(9), 1206-1212. doi:10.1093/oxfordjournals.humrep.a137513Cole, L. A. (2010). Biological functions of hCG and hCG-related molecules. Reproductive Biology and Endocrinology, 8(1), 102. doi:10.1186/1477-7827-8-102Devroey, P., Boostanfar, R., Koper, N. P., Mannaerts, B. M. J. L., IJzerman-Boon, P. C., & Fauser, B. C. J. M. (2009). A double-blind, non-inferiority RCT comparing corifollitropin alfa and recombinant FSH during the first seven days of ovarian stimulation using a GnRH antagonist protocol. Human Reproduction, 24(12), 3063-3072. doi:10.1093/humrep/dep291Drakakis, P., Loutradis, D., Beloukas, A., Sypsa, V., Anastasiadou, V., Kalofolias, G., … Antsaklis, A. (2009). Early hCG addition to rFSH for ovarian stimulation in IVF provides better results and the cDNA copies of the hCG receptor may be an indicator of successful stimulation. Reproductive Biology and Endocrinology, 7(1). doi:10.1186/1477-7827-7-110Durnerin, C. I., Erb, K., Fleming, R., Hillier, H., Hillier, S. G., … Howles, C. M. (2007). Effects of recombinant LH treatment on folliculogenesis and responsiveness to FSH stimulation. Human Reproduction, 23(2), 421-426. doi:10.1093/humrep/dem388Estany, J., Camacho, J., Baselga, M., & Blasco, A. (1992). Selection response of growth rate in rabbits for meat production. Genetics Selection Evolution, 24(6), 527. doi:10.1186/1297-9686-24-6-527Ezcurra, D., & Humaidan, P. (2014). A review of luteinising hormone and human chorionic gonadotropin when used in assisted reproductive technology. Reproductive Biology and Endocrinology, 12(1), 95. doi:10.1186/1477-7827-12-95Fauser, B. C. J. M., Alper, M. M., Ledger, W., Schoolcraft, W. B., Zandvliet, A., & Mannaerts, B. M. J. L. (2010). Pharmacokinetics and follicular dynamics of corifollitropin alfa versus recombinant FSH during ovarian stimulation for IVF. Reproductive BioMedicine Online, 21(5), 593-601. doi:10.1016/j.rbmo.2010.06.032Franco, J. G., Baruffi, R. L., Oliveira, J. B. A., Mauri, A. L., Petersen, C. G., Contart, P., & Felipe, V. (2009). Effects of recombinant LH supplementation to recombinant FSH during induced ovarian stimulation in the GnRH-agonist protocol: a matched case-control study. Reproductive Biology and Endocrinology, 7(1). doi:10.1186/1477-7827-7-58HASHIMOTO, S., KURAMOCHI, T., AOYAGI, K., TAKAHASHI, R., UEDA, M., HIRAO, M., … HIRASAWA, K. (2004). Refined Porcine Follicle Stimulating Hormone Promotes the Responsiveness of Rabbits to Multiple-Ovulation Treatment. Experimental Animals, 53(4), 395-397. doi:10.1538/expanim.53.395Le Cotonnec, J.-Y., Porchet, H., Beltrami, V., & Munafo, A. (1998). Clinical pharmacology of recombinant human luteinizing hormone: Part I. Pharmacokinetics after intravenous administration to healthy female volunteers and comparison with urinary human luteinizing hormone. Fertility and Sterility, 69(2), 189-194. doi:10.1016/s0015-0282(97)00501-3Levy, D. P. (2000). The role of LH in ovarian stimulation: Exogenous LH: let’s design the future. Human Reproduction, 15(11), 2258-2265. doi:10.1093/humrep/15.11.2258Mannaerts, B. M., Geurts, T. B., & Odink, J. (1998). A randomized three-way cross-over study in healthy pituitary-suppressed women to compare the bioavailability of human chorionic gonadotrophin (Pregnyl) after intramuscular and subcutaneous administration. Human Reproduction, 13(6), 1461-1464. doi:10.1093/humrep/13.6.1461Rao, C. V. (1979). DIFFERENTIAL PROPERTIES OF HUMAN CHORIONIC GONADOTROPHIN AND HUMAN LUTEINIZING HORMONE BINDING TO PLASMA MEMBRANES OF BOVINE CORPORA LUTEA. Acta Endocrinologica, 90(4), 696-710. doi:10.1530/acta.0.0900696Ruvolo, G., Bosco, L., Pane, A., Morici, G., Cittadini, E., & Roccheri, M. C. (2007). Lower apoptosis rate in human cumulus cells after administration of recombinant luteinizing hormone to women undergoing ovarian stimulation for in vitro fertilization procedures. Fertility and Sterility, 87(3), 542-546. doi:10.1016/j.fertnstert.2006.06.059Salvetti, P., Theau-Clément, M., Beckers, J.-F., Hurtaud, J., Guérin, P., Neto, V., … Joly, T. (2007). Effect of the luteinizing hormone on embryo production in superovulated rabbit does. Theriogenology, 67(6), 1185-1193. doi:10.1016/j.theriogenology.2007.01.013Sen, A. (2013). Oocyte Maturation A story of arrest and release. Frontiers in Bioscience, S5(2), 451-477. doi:10.2741/s383Vicente, J. S., Viudes-de-Castro, M. P., Cedano-Castro, J. I., & Marco-Jiménez, F. (2018). Cryosurvival of rabbit embryos obtained after superovulation with corifollitropin alfa with or without LH. Animal Reproduction Science, 192, 321-327. doi:10.1016/j.anireprosci.2018.03.034Vicente, J.-S., Viudes-de-Castro, M.-P., & García, M.-L. (1999). In vivo survival rate of rabbit morulae after vitrification in a medium without serum protein. Reproduction Nutrition Development, 39(5-6), 657-662. doi:10.1051/rnd:19990511Viudes De Castro, M. P., Cortell, C., Mocé, E., Marco-Jiménez, F., Joly, T., & Vicente, J. S. (2009). Effect of recombinant gonadotropins on embryo quality in superovulated rabbit does and immune response after repeated treatments. Theriogenology, 72(5), 655-662. doi:10.1016/j.theriogenology.2009.04.022Viudes-de-Castro, M. P., Marco-Jiménez, F., Cedano-Castro, J. I., & Vicente, J. S. (2017). Effect of corifollitropin alfa supplemented with or without LH on ovarian stimulation and embryo viability in rabbit. Theriogenology, 98, 68-74. doi:10.1016/j.theriogenology.2017.05.005Viudes-de-Castro, M. P., Pomares, A., Saenz de Juano i Ribes, M. D., Marco-Jiménez, F., & Vicente, J. S. (2015). Effect of luteinizing hormone on rabbit ovarian superstimulation and embryo developmental potential. Theriogenology, 84(3), 446-451. doi:10.1016/j.theriogenology.2015.04.001Wallach, E. E., Shoham, Z., Schachter, M., Loumaye, E., Weissman, A., MacNamee, M., & Insler, V. (1995). The luteinizing hormone surge—the final stage in ovulation induction: modern aspects of ovulation triggering. Fertility and Sterility, 64(2), 237-251. doi:10.1016/s0015-0282(16)57717-