Vývoj metody na stanovení steroidních látek ve vodách

The theoretical part of the Master´s thesis describes steroids, their features, and the methods for their determination in waters. In experimental part three steroid hormones, namely 1,4-androstadiene-3,17-dione (ADD), 1,4-androstadiene-3-one-17(beta)-ol (boldenone) and 17(beta)-estradiol were selected. The compounds were concentrated from water by LLE and SPE extraction and determined by gas chromatography coupled to mass spectrometry. Several experiments were conducted to assess the recovery of specific extraction for studied compound

The study of segmental dynamics of selected fluorinated methacrylates using solid state NMR

The theoretical part of the Bachelor thesis describes the principles of nuclear magnetic spectroscopy (NMR spectroscopy) and the usage of the method for measurements of gel electrolytes characteristics. The experimental part was focused on preparation and NMR specroscopy examination of two samples of polymer gel electrolytes differring in the content of liquid phase and therefore in interactions and conductivity

Použitelnost výpočetních metod kvantové chemie pro studium interakcí v biologických systémech

The theoretical part of the Master´s thesis describes ab initio methods in quantum chemistry and semiempirical methods, which represents a way in overcoming of main disadvantages in ab initio methods (costs, speed). The experimental part was focused on comparison highly accurate CCSD(T) method with used semiempirical methods (AM1, PM3, PM6, and PM7). The data were mostly compared on small model systems with ions, which are an essential part of many biological systems. Furthermore, the applicability of semiempirical methods was examined for the description of intra- and intermolecular hydrogen bonds and van der Waals interactions