Radiologists as co-authors in case reports : does their involvement make a difference?

Background: Due to their crucial role in many diagnostic processes, a considerable number of papers in non-radiological medical journals contain images. We noticed that radiologists are seldom mentioned as co-authors. Purpose: To investigate how often radiologists are involved as co-authors and to measure the influence of their involvement on the choice and quality of the illustrations and captions. Material and Methods: We queried PubMed for papers in English with the search string "case report" in the title, examined them for the presence of radiological images, and excluded those published in radiological journals. We developed a scoring system, containing objective and subjective qualification criteria. In addition, we checked if a radiologist was involved as co-author, or mentioned in the Acknowledgments section. We performed a statistical analysis to check if the involvement of a radiologist had a significant effect on the overall quality of the case report. Results: In 21% (45/218) of the papers, a radiologist was mentioned as co-author and in 3% (7/218) a radiologist was mentioned in the acknowledgments. In 76% (166/218), radiologists were neither involved as co-authors, nor mentioned in acknowledgments. We found statistically significant quality differences between these three groups (P < 0.001). Conclusion: This study indicated that the quality of case reports can be improved when radiologists are involved in the preparation and publication of papers containing imaging studies

Prevalence of knowledge about the OC.

<p>Prevalence of knowing the period of the highest fertility during the ovulatory cycle. Data from six cross-sectional surveys during 1988–2008 in Egyptian women aged 15–49.</p

Mature CD10+ and immature CD10- neutrophils present in G-CSF-treated donors display opposite effects on T cells

The identification of discrete neutrophil populations, as well as the characterization of their immunoregulatory properties, is an emerging topic under extensive investigation. In such regard, the presence of circulating CD66b+ neutrophil populations, exerting either immunosuppressive or proinflammatory functions, has been described in several acute and chronic inflammatory conditions. However, due to the lack of specific markers, the precise phenotype and maturation status of these neutrophil populations remain unclear. Herein, we report that CD10, also known as common acute lymphoblastic leukemia antigen, neutral endopeptidase, or enkephalinase, can be used as a marker that, within heterogeneous populations of circulating CD66b+ neutrophils present in inflammatory conditions, clearly distinguishes the mature from the immature ones. Accordingly, we observed that the previously described immunosuppressive neutrophil population that appears in the circulation of granulocyte colony-stimulating factor (G-CSF)-treated donors (GDs) consists of mature CD66b+CD10+ neutrophils displaying an activated phenotype. These neutrophils inhibit proliferation and interferon \u3b3 (IFN\u3b3) production by T cells via a CD18-mediated contact-dependent arginase 1 release. By contrast, we found that immature CD66b+CD10- neutrophils, also present in GDs, display an immature morphology, promote T-cell survival, and enhance proliferation and IFN\u3b3 production by T cells. Altogether, our findings uncover that in GDs, circulating mature and immature neutrophils, distinguished by their differential CD10 expression, exert opposite immunoregulatory properties. Therefore, CD10 might be used as a phenotypic marker discriminating mature neutrophils from immature neutrophil populations present in patients with acute or chronic inflammatory conditions, as well as facilitating their isolation, to better define their specific immunoregulatory properties