118 research outputs found

    Creating a Reference Model for the Creative Industries – Evaluation of Configurable Event Driven Process Chains in Practice

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    The Australian screen business is facing new challenges to stay competitive. Increasing globalization on the one hand offers new opportunities for service-related companies but on the other hand raises the competition in drawing the attention of production companies. Motivated by a lack of process-centered management support, this work aims to deliver a starting point for an application of Business Process Management principles and practices within the Creative Industries to help facing the new challenges. I therefore present a reference process model for the post production part of screen business productions. To allow for comprehensive adaptation to project-specific scenarios or a company’s requirements the model is developed as Configurable Even-Driven Process Chain. The designated reference modeling language provides means to clearly specify process variations. In a second step I use the application in a real-life case to contribute to the empirical validation of the modeling language and to reflect on the relevance and completeness of the language

    Understanding the Performance Impact of Enterprise Architecture Management

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    Enterprise architecture management (EAM) is becoming a widely accepted management approach deemed to improve, among others, the long-term development of organizations’ IT and the performance of corporate IT functions. Profound EAM often requires a significant amount of financial and human resources. Therefore, practitioners and researchers alike aim to understand the mechanisms that lead to the desired benefits. However, the way in which EAM generates value is not yet sufficiently understood and the related research lacks a theoretical foundation. We argue that the resource-based theory (RBT) is well suited to explain the influence of EAM on the performance of corporate IT functions and present a framework that helps elucidate this impact. We report on a single case study that we conducted at a large professional service firm. The empirical results identify a first set of causal relationships between the theoretical framework’s elements. The study\u27s findings make it possible for practitioners to better understand the performance impacts of EAM. This work is part of ongoing exploratory research aimed at explaining the mechanisms through which EAM affects firm performance within a testable theory

    A new target preparation facility for high precision AMS measurements and strategies for efficient 14CO2 sampling

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    The aim of this thesis was to allow for the processing of large-scale atmospheric 14CO2 samples into graphite targets for high-precision analysis on an accelerator mass spectrometer (AMS) and to further develop the sampling itself, which takes place throughout Europe within the Integrated Carbon Observation System (ICOS) network. For the first part, a largely automated Extraction and Graphitisation Line (EGL) was developed at the ICOS Central Radiocarbon Laboratory(CRL); the construction at the institute workshop was guided and process behaviour and target quality was characterised. Process fractionation in δ13C from the whole-air sample flask to the graphite target cannot be distinguished from zero with (0.04 ± 0.09)‰. The deviation from the absolute canonical Δ14C scale was determined to (0.7 ± 0.5)‰. It was shown that the reproducibility of Δ14C results from processed air samples is at ±1.9‰ or below for the final graphitisation parameters. Compatibility tests provided a deviation of the results of samples processed with EGL and analysed by the AMS at the Curt-Engelhorn-Centre Archaeometry (CEZ) from the results of the CRL Low-Level Counting (LLC) laboratory of (2.2 ± 0.9)‰. The reason for the deviation is currently unknown. For the further development of 14CO2 sampling, a new trajectory-triggered strategy was simulated in an atmospheric forward modelling system. It was shown that weak fossil CO2 signals from emission hotspots at four German ICOS stations can be amplified by a factor of up to 7, while the signal background is estimated with parallely taken samples

    Weiterbildungsstatistik im Verbund: Ergebnisse für das Berichtsjahr 2018

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    Das Deutsche Institut für Erwachsenenbildung erhebt jedes Jahr die Daten zu öffentlich finanzierten Weiterbildungsangeboten in Deutschland. Die Statistiken enthalten aktuelle Informationen zu institutionellen Merkmalen, zu Personal und Finanzen, zum Leistungsspektrum durchgeführter Veranstaltungen und umfangreiche Daten zu den Teilnehmenden. Kooperationspartner:innen der Statistik sind der Bundesarbeitskreis Arbeit und Leben (BAK AL), die Deutsche Evangelische Arbeitsgemeinschaft für Erwachsenenbildung (DEAE), die Katholische Bundesarbeitsgemeinschaft Erwachsenenbildung (KEB) sowie der Deutsche Volkshochschul-Verband e.V. (DVV)

    Weiterbildungsstatistik im Verbund

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    Die Langzeitstatistik präsentiert Daten zu öffentlich finanzierten Weiterbildungsangeboten in Deutschland, die jährlich vom Deutschen Institut für Erwachsenenbildung (DIE) erhoben und ausgewertet werden. Die Statistiken informieren über die Entwicklung in Institutionen, bei Personal und Finanzen, zum Leistungsspektrum durchgeführter Veranstaltungen sowie zu den Teilnehmenden. Die Statistik wird in Kooperation mit dem Bundesarbeitskreis Arbeit und Leben (BAK AL), der Deutschen Evangelischen Arbeitsgemeinschaft für Erwachsenenbildung (DEAE), der Katholischen Bundesarbeitsgemeinschaft Erwachsenenbildung (KEB) sowie dem Deutschen Volkshochschul-Verband e.V. (DVV) erstellt

    Weiterbildungsstatistik im Verbund 2017 - Kompakt

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    Das Deutsche Institut für Erwachsenenbildung erhebt jedes Jahr die Daten zu öffentlich finanzierten Weiterbildungsangeboten in Deutschland. Die Statistiken enthalten aktuelle Informationen zu institutionellen Merkmalen, zu Personal und Finanzen, zum Leistungsspektrum durchgeführter Veranstaltungen und umfangreiche Daten zu den Teilnehmenden. Kooperationspartner:innen der Statistik sind der Bundesarbeitskreis Arbeit und Leben (BAK AL), die Deutsche Evangelische Arbeitsgemeinschaft für Erwachsenenbildung (DEAE), die Katholische Bundesarbeitsgemeinschaft Erwachsenenbildung (KEB) sowie der Deutsche Volkshochschul-Verband e.V. (DVV)

    Evolution of MPCV Service Module Propulsion and GNC Interface Requirements

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    The Orion Multi-Purpose Crew Vehicle Service Module Propulsion Subsystem provides propulsion for the integrated Crew and Service Module. Updates in the exploration architecture between Constellation and MPCV as well as NASA's partnership with the European Space Agency have resulted in design changes to the SM Propulsion Subsystem and updates to the Propulsion interface requirements with Guidance Navigation and Control. This paper focuses on the Propulsion and GNC interface requirement updates between the Constellation Service Module and the European Service Module and how the requirement updates were driven or supported by architecture updates and the desired use of hardware with heritage to United States and European spacecraft for the Exploration Missions, EM-1 and EM-2

    Transdisciplinary Sustainability Research and Citizen Science: Options for Mutual Learning.

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    Both citizen science and transdisciplinary sustainability research involve non-academic actors in the production of knowledge while seeking to contribute to sustainability transitions, albeit in different ways. From citizen science, transdisciplinary researchers can learn about the multiple ways of engaging knowledge holders, and producing and sharing knowledge

    Epigenetic silencing of serine protease HTRA1 drives polyploidy

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    Background: Increased numbers and improperly positioned centrosomes, aneuploidy or polyploidy, and chromosomal instability are frequently observed characteristics of cancer cells. While some aspects of these events and the checkpoint mechanisms are well studied, not all players have yet been identified. As the role of proteases other than the proteasome in tumorigenesis is an insufficiently addressed question, we investigated the epigenetic control of the widely conserved protease HTRA1 and the phenotypes of deregulation. Methods: Mouse embryonal fibroblasts and HCT116 and SW480 cells were used to study the mechanism of epigenetic silencing of HTRA1. In addition, using cell biological and genetic methods, the phenotypes of downregulation of HTRA1 expression were investigated. Results: HTRA1 is epigenetically silenced in HCT116 colon carcinoma cells via the epigenetic adaptor protein MBD2. On the cellular level, HTRA1 depletion causes multiple phenotypes including acceleration of cell growth, centrosome amplification and polyploidy in SW480 colon adenocarcinoma cells as well as in primary mouse embryonic fibroblasts (MEFs). Conclusions: Downregulation of HTRA1 causes a number of phenotypes that are hallmarks of cancer cells suggesting that the methylation state of the HtrA1 promoter may be used as a biomarker for tumour cells or cells at risk of transformation

    Evolution of MPCV Service Module Propulsion and GN and C Interface Requirements

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    Presentation on the European Service Module mission description, propulsion subsystem, and propulsion and guidance navigation and control interface requirements. The content focuses on the updates to these areas between Constellation and the Multi-Purpose Crew Vehicle
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