342 research outputs found
Path integral representation of the evolution operator for the Dirac equation
A path integral representation of the evolution operator for the
four-dimensional Dirac equation is proposed. A quadratic form of the canonical
momenta regularizes the original representation of the path integral in the
electron phase space. This regularization allows to obtain a representation of
the path integral over trajectories in the configuration space, i.e. in the
Minkowsky space. This form of the path integral is useful for the formulation
of perturbation theory in an external electromagnetic field.Comment: 3 page
RECONSTRUCTING THE K0/S - MESON FROM THE FIRST DATA OF CMS EXPERIMENT
The Large Hadron Collider startup took place on November 2009 in CERN, at center-of-mass energies of 900 GeV for the colliding
protons. The results of processing the first data accumulated by CMS experiment are presented. For processing and analyzing the
track collections as well as the collection of identified particles have been used. The distributions of charged pions over their
transverse momentum and pseudorapidity are built. К0
s−meson mass is reconstructed in channel of К0/s decay to two charged pions. Comparison with results of computer simulation of proton-proton interactions in CMS detector is also done. It is shown that reconstruction of events is adequate
Influence of the quality of higher vocational education on the social and occupational mobility of youth
The urgency of the question of social and occupational mobility is defined. The terms «social mobility», «occupational mobility» and «social and occupational mobility» are considered. The acquirement of general cultural competencies is described as the important result of educational process. The quality of higher education is defined as an important condition of social and occupational mobilityОпределена актуальность вопроса социально-профессиональной мобильности молодежи. Рассмотрены понятия «социальная мобильность», «профессиональная мобильность» и «социально-профессиональная мобильность». Овладение студентами общекультурными компетенциями рассмотрено как важнейший результат образовательного процесса. Качество высшего образования определено как важное условие социально-профессиональной мобильност
Biofunctionalized magnetic microdiscs applied in medicine
The work was supported by the Russian Foundation for Basic Research, Government of Krasnoyarsk Territory, Krasnoyarsk Region Science and Technology Support Fund to the research project № 18-32-00035\18
Fabrication process for producing silicon nanowire field effect transistors
The work was supported by the Russian Foundation for Basic Research, Government of Krasnoyarsk Territory, Krasnoyarsk Region Science and Technology Support Fund project no. 18-42-243022. This work is partially supported by the Ministry of Education and Science of the Russian Federation and by Siberian Branch of the Russian Academy of Sciences (Project II.8.70) and Fundamental research program of the Presidium of the RAS no. 32 «Nanostructures: physics, chemistry, biology, basics of technologies». This work was supported by and carried out on the equipment of the Center for Common Use of the Krasnoyarsk Scientific Center, Siberian Branch, Russian Academy of Sciences
Molecular-genetic testing of single-nucleotide polymorphism C-33T of IL4 gene in children with recurrent episodes of acute obstructive bronchitis.
The molecular genetic testing of the IL4 gene of a single nucleotide polymorphism C-33T was performed in 35 children with recurrent episodes of acute obstructive bronchitis and 35 children with acute bronchitis. It has been proved that the presence of a child's genotype 33СT IL4 increases the risk of recurrent acute obstructive bronchitis by 4 times
Subcellular heterogeneity of ryanodine receptor properties in ventricular myocytes with low T-tubule density
Rationale:
In ventricular myocytes of large mammals, not all ryanodine receptor (RyR) clusters are associated with T-tubules (TTs); this fraction increases with cellular remodeling after myocardial infarction (MI).
Objective:
To characterize RyR functional properties in relation to TT proximity, at baseline and after MI.
Methods:
Myocytes were isolated from left ventricle of healthy pigs (CTRL) or from the area adjacent to a myocardial infarction (MI). Ca2+ transients were measured under whole-cell voltage clamp during confocal linescan imaging (fluo-3) and segmented according to proximity of TTs (sites of early Ca2+ release, F>F50 within 20 ms) or their absence (delayed areas). Spontaneous Ca2+ release events during diastole, Ca2+ sparks, reflecting RyR activity and properties, were subsequently assigned to either category.
Results:
In CTRL, spark frequency was higher in proximity of TTs, but spark duration was significantly shorter. Block of Na+/Ca2+ exchanger (NCX) prolonged spark duration selectively near TTs, while block of Ca2+ influx via Ca2+ channels did not affect sparks properties. In MI, total spark mass was increased in line with higher SR Ca2+ content. Extremely long sparks (>47.6 ms) occurred more frequently. The fraction of near-TT sparks was reduced; frequency increased mainly in delayed sites. Increased duration was seen in near-TT sparks only; Ca2+ removal by NCX at the membrane was significantly lower in MI.
Conclusion:
TT proximity modulates RyR cluster properties resulting in intracellular heterogeneity of diastolic spark activity. Remodeling in the area adjacent to MI differentially affects these RyR subpopulations. Reduction of the number of sparks near TTs and reduced local NCX removal limit cellular Ca2+ loss and raise SR Ca2+ content, but may promote Ca2+ waves
Assessment of the epidemic situation in the incidence of Siberian tick-borne typhus in the Altai Krai
The article presents the results of a retrospective epidemiological analysis of the incidence of the population of the Altai Territory by Siberian tick-borne typhus (STBT), which is endemic in this region of the Siberian Federal District. The epidemiological situation of STBT in the urban and rural areas of the region was assessed in the period from 2000 to 2017. Specific features of the incidence of STBT among adults and children's age cohorts of the population are determined. An assessment is made of the relationship between the trend in the dynamics of the incidence of STBT and the number of people who have suffered from tick bites.В статье представлены результаты ретроспективного эпидемиологического анализа заболеваемости населения Алтайского края сибирским клещевым тифом (СКТ), как эндемичного по данной инфекции региона Сибирского федерального округа. Дана оценка эпидемической ситуации по СКТ в городских и сельских территориях региона в период с 2000 по 2017 годы. Определены особенности заболеваемости СКТ среди взрослой и детской возрастных когорт населения. Представлена оценка взаимосвязи между тенденцией динамики заболеваемости СКТ и числом пострадавших от укусов клещей лиц
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