Neuropsychological approach to subjective cognitive complaints in cognitively unimpaired older people: a systematic review

Objective: a systemized approach to subjective cognitive complaints (SCCs) in elderly people is needed owing to the high prevalence of such complaints and their impact on the psychosocial well-being of those affected. The aim of this study was to carry out a systematic review of the characteristics and effectiveness of intervention programmes that use a neuropsychological approach to target SCCs in cognitively unimpaired older people and that are tested in randomized controlled trials.Methods: the search included a time-unlimited query of Scopus, PsycInfo and Medline, yielding 215 articles, of which only 7 met the inclusion/exclusion criteria. Results: the number of intervention programmes was very limited (11 interventions), but diverse, with cognitive stimulation, physical exercise, psychoeducation and cognitive restructuring all used to address SCCs. Conclusions: interventions including only cognitive stimulation were not effective in reducing SCCs, but interventions including cognitive stimulation and psychoeducation, physical exercise, and group sessions and discussions reinforced by the therapist were effectiveS

Efectividad de la tintura de caléndula al 20% en afecciones dermatológicas

A quasi-experimental, prospective, longitudinal study was conducted at the National Hospital of Nebaj, Guatemala, during the period December 2011 to December 2012 to determine the effectiveness of calendula tincture to 20% in the treatment of furunculosis and contact dermatitis and atopic. Patients previously diagnosed by a Specialist in General Medicine in the outpatient formed the study population; the sample was selected by purposive sampling method and patients were divided into study group (calendula tincture to 20%) and control group (conventional medicine). At the beginn, they were evaluating, seven, 14 and 21 days and the clinical outcome were observed, recovery time and adverse reactions to treatment. In 88.1% of patients in the study group had successful outcomes dermal lesions compared with 71.4% in the control group; all patients with boils in the study group were recovered from seven to 14 days of treatment, as opposed to 80% in the control group; with calendula tincture to 20% presented adverse reactions  in 2.4% of patients with conventional treatment in 26.2%. The treatment in the study group was effective in 88.1% of patients while in the control group was effective in 66.7%; differences were significant (p = 0.04). Calendula tincture to 20% was effective in the treatment of furunculosis and contact and atopic dermatitis.Se realizó un estudio cuasi-experimental, prospectivo y longitudinal en el Hospital Nacional de Nebaj, Guatemala, en el período de diciembre de 2011 a diciembre de 2012 para determinar la efectividad de la tintura de caléndula al 20% en el tratamiento de las forunculosis y las dermatitis de contacto y atópicas. Los pacientes previamente diagnosticados por el Especialista en Medicina General Integral en la consulta externa conformaron la población de estudio; la muestra se seleccionó por el método de muestreo intencional y se dividieron los pacientes en grupo estudio (tintura de caléndula al 20%) y grupo control (medicamentos convencionales). Se evaluaron al inicio, a los siete, los 14 y los 21 días y se observaron la evolución clínica, el tiempo de recuperación y las reacciones adversas al tratamiento. En el 88.1% de los pacientes del grupo estudio las lesiones dérmicas evolucionaron satisfactoriamente en comparación con el 71.4% del grupo control; todos los enfermos con forúnculos del grupo estudio se recuperaron entre los siete y los 14 días de tratamiento, a diferencia del 80% en el grupo control; con la tintura de caléndula al 20% se presentaron reacciones adversas en el 2.4% de los pacientes y con el tratamiento convencional en el 26.2%. El tratamiento en el grupo estudio resultó ser efectivo en el 88.1% de los enfermos mientras en el grupo control fue efectivo en el 66.7%; las diferencias fueron significativas (p=0.04). La tintura de caléndula al 20% resultó efectiva en el tratamiento de las forunculosis y las dermatitis de contacto y atópicas

Obxectivo de desenvolvemento sostble 11: desenvolvemento de políticas rurais e urbanas

Traballo realizado para a materia Desenvolvemento Rexional e Desenvolvemento Local do Grao en Economía en virtude do Proxecto de Aprendizaxe-Servizo. Curso 2020-2021Primeiro, contextualízase o territorio do Concello de Santiago de Compostela ;o que servirá de base para entender parte das conclusión dos apartados posteriores. Despois, explícase o obxectivo principal do traballo e a aplicación do ODS número 11 en Santiago de Compostela, mediante a súa integración nos vectores estratéxicos da Axenda Urbana do Eixo Atlántico xunto coa Estratexia de Desenvolvemento Urbano Sostible e Integrado (EDUSI). A continuación, coméntanse os puntos identificados na EDUSI e se as Axendas Urbanas coinciden coas necesidades reais dos cidadáns, a través dunha serie de entrevistas tanto a entidades locais, como a xente de Santiago.Para rematar, fanse unha serie de propostas de longo prazo que se consideran de carácter urxente unha vez vistos os puntos anteriores e unhas conclusións finais sobre todo o recorrido da investigació

Marginal changes at bone-level implants supporting fixed screw-retained partial implant prostheses with or without intermediate standardised abutments: 1-year results of a randomised controlled clinical trial

Objective: To compare marginal changes at bone- level implants restored with screw- retained implant prosthesis with or without intermediate standardised abutments, after 1 year of follow-up.Materials and Methods: Thirty- six partially edentulous patients received 72 implants. Each patient received 2 implants and a 2- to 4- unit screw- retained implant- prosthesis. The test group received implants consisting of a screw- retained prosthesis connected directly to the implant shoulder, while the prostheses in the control group were con-nected through a 3- mm standardised intermediate abutment. Clinical and radiological data were recorded at baseline and at 3, 6 and 12 months in follow-up visits.Results: At 12 months, the marginal bone loss was 0.17 ± 0.24 mm for the test group (19 patients) and 0.09 ± 0.15 mm for the control group (17 patients), with no statistically significant differences (p> .05). The mean probing pocket depth was 2.96 mm ± 0.46 for the test group and 2.86 ± 0.62 mm for the control group. The test and control groups showed bleeding on probing levels of 18.86 ± 14.12% and 13.73 ± 17.66%, re-spectively. All patients scored below 25% on the plaque index levels.Conclusions: Restoration of bone- level implants with fixed screw- retained partial prostheses with or without intermediate abutments presented similar radiographic and clinical outcomes after 1 yearS

Au@Ag SERRS tags coupled to a lateral flow immunoassay for the sensitive detection of pneumolysin

Establishing a definitive diagnosis of pneumonia using conventional tests is difficult and expensive. Lateral flow immunoassays (LFIAs) are an advantageous point of care (POC) test option, but they have some limitations in terms of detection and quantification. In this work we have developed a lateral flow immunoassay for the ultrasensitive detection of penumolysin employing plasmonic Surface-Enhanced Resonance Raman Scattering (SERRS) tag as labelled probe. The combination of Au@Ag core-shell nanoparticles as plasmonic platform and Rhodamine B Isothiocyanate as Raman reporter has allowed us to fabricate a SERRS tag with high efficiency and reliability. The limit of quantification of the SERRS-based LFIA was 1pg/mL, while the limit of detection was 3.6 pg/mL. This could be a strong foundation for a pneumonia diagnosis test based on pneumolysin detectio

Do informant-reported subjective cognitive complaints predict progression to mild cognitive impairment and dementia better than self-reported complaints in old adults? A meta-analytical study

Background: Subjective cognitive complaints (SCCs) are considered a risk factor for objective cognitive decline and conversion to dementia. The aim of this study was to determine whether self-reported or informant-reported SCCs best predict progression to mild cognitive impairment (MCI) and/or dementia. Methods: We reviewed prospective longitudinal studies of Cognitively Unimpaired (CU) older adults with self-reported and informant-reported SCCs at baseline, assessed by questions or questionnaires that considered the transition to MCI and/or dementia. A random-effects meta-analysis was performed to obtain pooled estimates and 95% CIs. Results: Both self-reported and informant-reported SCCs are associated with an elevated risk of transition from CU to MCI and/or dementia. The association appears stronger and more robust for informant-reported data [1.38, with a 95% CI of 1.16 –1.64, p < 0.001] than for self-reported data [1.27 (95% CI 1.06 – 1.534, p = 0.011]. Conclusions Our results suggest that corroborated information from one informant could provide important details for distinguishing between normal aging and clinical statesThis work was supported though FEDER founds by the Spanish National Research Agency (Spanish 'Ministry of Science, Innovation and Universities) (Project Ref. PSI2017-89389-C2-1-R), FEDER founds (‘A way to make Europe’) by the Spanish AEI (Doi: 10.13039/501100011033; Refs. PID2020-114521RB-C21 and PSI2017-89389-C2-1-R) and by the Galician Government (Consellería de Cultura, Educación e Ordenación Universitaria; axudas para a consolidación e estruturación de unidades de investigación competitivas do Sistema Universitario de Galicia; GI-1807-USC: Ref. ED431C 2021/04)S

Histological and histomorphometric study of human palatal mucosa: implications for connective tissue graft harvesting

Aims To analyse the histological structure and histomorphometric characteristics of human hard palatal mucosa in order to determine the donor site of choice for connective tissue grafts from a histological point of view. Materials and Methods Palatal mucosa samples from six cadaver heads were harvested at four sites: incisal, premolar, molar and tuberosity. Histological and immunohistochemical techniques were performed, as was histomorphometric analysis. Results In the current study, we found that the density and size of cells were higher in the superficial papillary layer, whereas the thickness of the collagen bundles increased in the reticular layer. Excluding the epithelium, the mean percentage of lamina propria (LP) and submucosa (SM) was 37% and 63%, respectively (p < .001). LP thickness showed similar values in the incisal, premolar and molar regions, and a significantly greater thickness in tuberosity (p < .001). The thickness of SM increased from incisal to premolar and molar, disappearing in the tuberosity (p < .001). Conclusions As dense connective tissue of LP is the tissue of choice for connective tissue grafts, the best donor site from a histological point of view is tuberosity because it is composed only of a thick LP without the presence of a loose submucosal layerS

Coordinación para el seguimiento de la titulación Máster en Prevención de Riesgos Laborales

La titulación de postgrado Máster en Prevención de Riesgos Laborales se implantó en la Escuela Politécnica Superior de la Universidad de Alicante en el curso 2011/12. El profesorado con docencia asignada en la titulación participó durante el curso 2012/13 en el proyecto para la coordinación de las asignaturas del Máster en Prevención de Riesgos Laborales. En el marco creado por los nuevos estudios de Postgrado, dentro del EEES, el proyecto tenía como objetivo principal la coordinación de las asignaturas y la mejora de la calidad docente. La implantación de la titulación generó un esfuerzo considerable por parte de los coordinadores y docentes implicados, que adaptaron su planificación y metodología al nuevo marco del EEES. El diseño de las asignaturas del Máster ha incorporado la metodología, el cronograma del temario y la evaluación durante todas las semanas del semestre. En este sentido se tuvieron que solucionar diferentes problemas: compatibilizar horarios de los docentes, evitar solapamientos entre asignaturas y verificar la información completa de cada asignatura. El proyecto de coordinación ha resultado un instrumento útil para la interacción y coordinación entre los profesores/as con participación docente en el Máster