Sustaining Working Rangelands: Insights from Rancher Decision Making

Grazed rangeland ecosystems encompass diverse global land resources and are complex social-ecological systems from which society demands both goods (e.g., livestock and forage production) and services (e.g., abundant and high-quality water). Including the ranching community's perceptions, knowledge, and decision-making is essential to advancing the ongoing dialogue to define sustainable working rangelands. We surveyed 507 (33% response rate) California ranchers to gain insight into key factors shaping their decision-making, perspectives on effective management practices and ranching information sources, as well as their concerns. First, we found that variation in ranch structure, management goals, and decision making across California's ranching operations aligns with the call from sustainability science to maintain flexibility at multiple scales to support the suite of economic and ecological services they can provide. The diversity in ranching operations highlights why single-policy and management "panaceas" often fail. Second, the information resources ranchers rely on suggest that sustaining working rangelands will require collaborative, trust-based partnerships focused on achieving both economic and ecological goals. Third, ranchers perceive environmental regulations and government policies-rather than environmental drivers-as the major threats to the future of their operations

Military objectives in cyber warfare

This Chapter discusses the possible problems arising from the application of the principle of distinction under the law of armed conflict to cyber attacks. It first identifies when cyber attacks qualify as ‘attacks’ under the law of armed conflict and then examines the two elements of the definition of ‘military objective’ contained in Article 52(2) of the 1977 Protocol I additional to the 1949 Geneva Conventions on the Protection of Victims of War. The Chapter concludes that this definition is flexible enough to apply in the cyber context without significant problems and that none of the challenges that characterize cyber attacks hinders the application of the principle of distinction

Melioidosis Vaccines: A Systematic Review and Appraisal of the Potential to Exploit Biodefense Vaccines for Public Health Purposes

The designation of Burkholderia pseudomallei as a category B select agent has resulted in considerable research funding to develop a protective vaccine. This bacterium also causes a naturally occurring disease (melioidosis), an important cause of death in many countries including Thailand and Australia. In this study, we explored whether a vaccine could be used to provide protection from melioidosis. An economic evaluation based on its use in Thailand indicated that a vaccine could be a cost-effective intervention if used in high-risk populations such as diabetics and those with chronic kidney or lung disease. A literature search of vaccine studies in animal models identified the current candidates, but noted that models failed to take account of the common routes of infection in natural melioidosis and major risk factors for infection, primarily diabetes. This review highlights important areas for future research if biodefence-driven vaccines are to play a role in reducing the global incidence of melioidosis

Increasing flexibility in rangeland management during drought

Extreme droughts like the recent 2011-2013 drought impacting the central and western United States present a challenge to sustaining livestock ranching operations and the ecosystem goods and services they produce. Wyoming ranchers manage half of this drought-prone state and are at the forefront of this challenge. We examined Wyoming ranchers' drought management strategies and how ranch characteristics affect drought management flexibility, a key component of resilience, through a mail survey. We find that many survey respondents manage drought in similar ways, by selling livestock and buying feed, highlighting the market risks associated with drought. Ranches that are larger, include yearling livestock, use shorter grazing periods, and/or incorporate alternative on-ranch activities (e.g., hunting) use more drought management practices and thus have greater flexibility. Larger ranches experience fewer drought impacts, highlighting advantages of a larger resource base. Our findings suggest three components of national drought policy that encourages flexibility and thus increases resilience of ranches to drought: (1) encouraging forage-sharing mechanisms; (2) promoting income diversification that is independent of climatic variability; and (3) facilitating a shift to diversified livestock production systems. These measures could increase sustainability of ranching livelihoods and provision of ecosystem services despite predicted increases in intensity and duration of future droughts. © 2014 Kachergis et al

Increasing flexibility in rangeland management during drought

Extreme droughts like the recent 2011-2013 drought impacting the central and western United States present a challenge to sustaining livestock ranching operations and the ecosystem goods and services they produce. Wyoming ranchers manage half of this drought-prone state and are at the forefront of this challenge. We examined Wyoming ranchers' drought management strategies and how ranch characteristics affect drought management flexibility, a key component of resilience, through a mail survey. We find that many survey respondents manage drought in similar ways, by selling livestock and buying feed, highlighting the market risks associated with drought. Ranches that are larger, include yearling livestock, use shorter grazing periods, and/or incorporate alternative on-ranch activities (e.g., hunting) use more drought management practices and thus have greater flexibility. Larger ranches experience fewer drought impacts, highlighting advantages of a larger resource base. Our findings suggest three components of national drought policy that encourages flexibility and thus increases resilience of ranches to drought: (1) encouraging forage-sharing mechanisms; (2) promoting income diversification that is independent of climatic variability; and (3) facilitating a shift to diversified livestock production systems. These measures could increase sustainability of ranching livelihoods and provision of ecosystem services despite predicted increases in intensity and duration of future droughts. © 2014 Kachergis et al

Climate-smart agriculture global research agenda: scientific basis for action

Climate-smart agriculture (CSA) addresses the challenge of meeting the growing demand for food, fibre and fuel, despite the changing climate and fewer opportunities for agricultural expansion on additional lands. CSA focuses on contributing to economic development, poverty reduction and food security; maintaining and enhancing the productivity and resilience of natural and agricultural ecosystem functions, thus building natural capital; and reducing trade-offs involved in meeting these goals. Current gaps in knowledge, work within CSA, and agendas for interdisciplinary research and science-based actions identified at the 2013 Global Science Conference on Climate-Smart Agriculture (Davis, CA, USA) are described here within three themes: (1) farm and food systems, (2) landscape and regional issues and (3) institutional and policy aspects. The first two themes comprise crop physiology and genetics, mitigation and adaptation for livestock and agriculture, barriers to adoption of CSA practices, climate risk management and energy and biofuels (theme 1); and modelling adaptation and uncertainty, achieving multifunctionality, food and fishery systems, forest biodiversity and ecosystem services, rural migration from climate change and metrics (theme 2). Theme 3 comprises designing research that bridges disciplines, integrating stakeholder input to directly link science, action and governance

Short-course primaquine for the radical cure of Plasmodium vivax malaria: a multicentre, randomised, placebo-controlled non-inferiority trial

Background Primaquine is the only widely used drug that prevents Plasmodium vivax malaria relapses, but adherence to the standard 14-day regimen is poor. We aimed to assess the efficacy of a shorter course (7 days) of primaquine for radical cure of vivax malaria. Methods We did a randomised, double-blind, placebo-controlled, non-inferiority trial in eight health-care clinics (two each in Afghanistan, Ethiopia, Indonesia, and Vietnam). Patients (aged ≥6 months) with normal glucose-6-phosphate dehydrogenase (G6PD) and presenting with uncomplicated vivax malaria were enrolled. Patients were given standard blood schizontocidal treatment and randomly assigned (2:2:1) to receive 7 days of supervised primaquine (1·0 mg/kg per day), 14 days of supervised primaquine (0·5 mg/kg per day), or placebo. The primary endpoint was the incidence rate of symptomatic P vivax parasitaemia during the 12-month follow-up period, assessed in the intention-to-treat population. A margin of 0·07 recurrences per person-year was used to establish non-inferiority of the 7-day regimen compared with the 14-day regimen. This trial is registered at ClinicalTrials.gov (NCT01814683). Findings Between July 20, 2014, and Nov 25, 2017, 2336 patients were enrolled. The incidence rate of symptomatic recurrent P vivax malaria was 0·18 (95% CI 0·15 to 0·21) recurrences per person-year for 935 patients in the 7-day primaquine group and 0·16 (0·13 to 0·18) for 937 patients in the 14-day primaquine group, a difference of 0·02 (−0·02 to 0·05, p=0·3405). The incidence rate for 464 patients in the placebo group was 0·96 (95% CI 0·83 to 1·08) recurrences per person-year. Potentially drug-related serious adverse events within 42 days of starting treatment were reported in nine (1·0%) of 935 patients in the 7-day group, one (0·1%) of 937 in the 14-day group and none of 464 in the control arm. Four of the serious adverse events were significant haemolysis (three in the 7-day group and one in the 14-day group). Interpretation In patients with normal G6PD, 7-day primaquine was well tolerated and non-inferior to 14-day primaquine. The short-course regimen might improve adherence and therefore the effectiveness of primaquine for radical cure of P vivax malaria.</p