565 research outputs found

    Density fluctuations and phase separation in a traffic flow model

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    Within the Nagel-Schreckenberg traffic flow model we consider the transition from the free flow regime to the jammed regime. We introduce a method of analyzing the data which is based on the local density distribution. This analyzes allows us to determine the phase diagram and to examine the separation of the system into a coexisting free flow phase and a jammed phase above the transition. The investigation of the steady state structure factor yields that the decomposition in this phase coexistence regime is driven by density fluctuations, provided they exceed a critical wavelength.Comment: in 'Traffic and Granular Flow 97', edited by D.E. Wolf and M. Schreckenberg, Springer, Singapore (1998

    Selection and validation of potato candidate genes for maturity corrected resistance to Phytophthora infestans based on differential expression combined with SNP association and linkage mapping.

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    Late blight of potato (Solanum tuberosum L.) caused by the oomycete Phytophthora infestans (Mont.) de Bary, is one of the most important bottlenecks of potato production worldwide. Cultivars with high levels of durable, race unspecific, quantitative resistance are part of a solution to this problem. However, breeding for quantitative resistance is hampered by the correlation between resistance and late plant maturity, which is an undesirable agricultural attribute. The objectives of our research are (i) the identification of genes that condition quantitative resistance to P. infestans not compromised by late plant maturity and (ii) the discovery of diagnostic single nucleotide polymorphism (SNP) markers to be used as molecular tools to increase efficiency and precision of resistance breeding. Twenty two novel candidate genes were selected based on comparative transcript profiling by SuperSAGE (serial analysis of gene expression) in groups of plants with contrasting levels of maturity corrected resistance (MCR). Reproducibility of differential expression was tested by quantitative real time PCR and allele specific pyrosequencing in four new sets of genotype pools with contrasting late blight resistance levels, at three infection time points and in three independent infection experiments. Reproducibility of expression patterns ranged from 28 to 97%. Association mapping in a panel of 184 tetraploid cultivars identified SNPs in five candidate genes that were associated with MCR. These SNPs can be used in marker-assisted resistance breeding. Linkage mapping in two half-sib families (n = 111) identified SNPs in three candidate genes that were linked with MCR. The differentially expressed genes that showed association and/or linkage with MCR putatively function in phytosterol synthesis, fatty acid synthesis, asparagine synthesis, chlorophyll synthesis, cell wall modification, and in the response to pathogen elicitors

    ETD on small intact proteins in an ultra high resolution quadrupole TOF mass spectrometer

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    A supercritical series analysis for the generalized contact process with diffusion

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    We study a model that generalizes the CP with diffusion. An additional transition is included in the model so that at a particular point of its phase diagram a crossover from the directed percolation to the compact directed percolation class will happen. We are particularly interested in the effect of diffusion on the properties of the crossover between the universality classes. To address this point, we develop a supercritical series expansion for the ultimate survival probability and analyse this series using d-log Pad\'e and partial differential approximants. We also obtain approximate solutions in the one- and two-site dynamical mean-field approximations. We find evidences that, at variance to what happens in mean-field approximations, the crossover exponent remains close to ϕ=2\phi=2 even for quite high diffusion rates, and therefore the critical line in the neighborhood of the multicritical point apparently does not reproduce the mean-field result (which leads to ϕ=0\phi=0) as the diffusion rate grows without bound

    Disorder-induced phase transition in a one-dimensional model of rice pile

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    We propose a one-dimensional rice-pile model which connects the 1D BTW sandpile model (Phys. Rev. A 38, 364 (1988)) and the Oslo rice-pile model (Phys. Rev. lett. 77, 107 (1997)) in a continuous manner. We found that for a sufficiently large system, there is a sharp transition between the trivial critical behaviour of the 1D BTW model and the self-organized critical (SOC) behaviour. When there is SOC, the model belongs to a known universality class with the avalanche exponent τ=1.53\tau=1.53.Comment: 10 pages, 7 eps figure

    Suscetibilidade in vitro a antifĂșngicos, de amostras clĂ­nicas e ambientais de Cryptococcus neoformans isoladas no sul do Brasil

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    The purpose of the present study was to compare the susceptibility to four antifungal agents of 69 Cryptococcus neoformans strains isolated from AIDS patients with that of 13 C. neoformans strains isolated from the environment. Based on the NCCLS M27-A methodology the Minimal Inhibitory Concentrations (MICs) obtained for amphotericin B, itraconazole and ketoconazole were very similar for clinical and environmental isolates. Clinical isolates were less susceptible to fluconazole than environmental isolates. The significance of these findings and aspects concerning the importance, role and difficulties of C. neoformans susceptibility testing are also discussed.Comparou-se a suscetibilidade de 69 amostras de C. neoformans isoladas de pacientes com SIDA com 13 amostras de C. neoformans isoladas do meio ambiente, frente a quatro agentes antifĂșngicos. Com base na metodologia preconizada pelo NCCLS (M27-A) as concentraçÔes inibitĂłrias mĂ­nimas (CIMs) obtidas para a anfotericina B, itraconazol e cetoconazol foram muito semelhantes nos dois grupos estudados. Todavia, frente ao fluconazol, os isolados clĂ­nicos evidenciaram menor sensibilidade do que os provenientes do meio ambiente. Alguns aspectos envolvendo a importĂąncia e dificuldades dos testes de suscetibilidade com Cryptococcus neoformans sĂŁo tambĂ©m discutidos pelos autores

    Distinct Scaling Regimes of Energy Release Dynamics in the Nighttime Magnetosphere

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    Based on a spatiotemporal analysis of POLAR UVI images, we show that the auroral emission events that initiate equatorward of the isotropic boundary (IB) obtained from a time-dependent empirical model, have systematically steeper power-law slopes of energy, power, area and lifetime probability distributions compared to the events that initiate poleward of the IB. The low-latitude group of events contains a distinct subpopulation of substorm-scale disturbances violating the power-law behavior, while the high latitude group is described by nearly perfect power-law statistics over the entire range of scales studied. The results obtained indicate that the inner and outer portions of the plasma sheet are characterized by substantially different scaling regimes of bursty energy dissipation suggestive of different physics in these regions.Comment: 11 pages, 2 figures, 2 table
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