216 research outputs found

    Diagnosis of bilateral trade between Colombia and China between the period 2001-2016

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    Esta muestra investigativa plantea un diagnóstico del comercio bilateral entre Colombia y China, exponiendo un enfoque analítico donde la investigación es la principal base de los datos económicos y comerciales entre estas dos naciones. El análisis ha demostrado que el valor del comercio bilateral entre Colombia y China ha aumentado año tras año, así como la dependencia del mercado, pero las diferencias de estructura comercial han dejado a Colombia en estado en déficit comercial. La relación comercial de China con Colombia es relativamente cercana, pero la de Colombia con China todavía no está lo suficientemente estrecha. La ventaja de las exportaciones colombianas sigue concentrada, fundamentalmente en productos primarios, y la de China ha mantenido una clara ventaja comparativa en productos manufacturados, en capital y en tecnología, aspecto que está aumentando gradualmente. En el comercio bilateral, Colombia cuenta con el comercio complementario en productos primarios, y China lo tiene en productos manufacturados. En medio del desarrollo del comercio bilateral entre Colombia y China, los factores geográficos, diplomáticos, políticos, económicos y comerciales tienen impactos favorables o desfavorables entre los dos países. Con base en el análisis de estos factores, se recomienda establecer una zona de libre comercio y promover el desarrollo del libre comercio, jugar con las respectivas ventajas comparativas, y mejorar la complementariedad del comercio bilateral, hacer pleno uso de los mecanismos de cooperación existentes y ampliar el comercio, mejorar la estructura comercial de exportación, mejorar la situación de seguridad y la infraestructura de Colombia, y promover el intercambio cultural entre Colombia y China.This research presents a diagnosis of bilateral trade between Colombia and China, exposing an analytical approach where research is the main basis of economic and commercial data between these two nations. The analysis has shown that the value of bilateral trade between Colombia and China has increased year after year, as well as market dependence, but the differences in commercial structure have left Colombia in trade deficit. China's trade relationship with Colombia is relatively close, but Colombia's relationship with China is still not close enough. The advantage of Colombian exports continues to be concentrated mainly in primary products, and China has maintained a clear comparative advantage in manufactured products, that in capital and technology is gradually increasing. In bilateral trade, Colombia has complementary trade in primary products, and China in products manufactured. In the course of bilateral trade development between Colombia and China, geographical, diplomatic, political, economic and commercial factors have favorable or unfavorable impacts on the commercial relationship between the two countries. Based on the analysis of bilateral trade of these factors, it is recommended to establish a free trade zone and promote the development of free trade between the two countries, play with the respective comparative advantages and improve the complementarity of bilateral trade, make full use of existing bilateral cooperation mechanisms and expand trade, deepen cooperation and improve export trade structure, improve the security situation and infrastructure of Colombia, and promote cultural exchange between Colombia and China.Magister en Administración de Empresas – MB

    Predictive assembling model reveals the self-adaptive elastic properties of lamellipodial actin networks for cell migration

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    Branched actin network supports cell migration through extracellular microenvironments. However, it is unknown how intracellular proteins adapt the elastic properties of the network to the highly varying extracellular resistance. Here we develop a three-dimensional assembling model to simulate the realistic self-assembling process of the network by encompassing intracellular proteins and their dynamic interactions. Combining this multiscale model with finite element method, we reveal that the network can not only sense the variation of extracellular resistance but also self-adapt its elastic properties through remodeling with intracellular proteins. Such resistance-adaptive elastic behaviours are versatile and essential in supporting cell migration through varying extracellular microenvironments. The bending deformation mechanism and anisotropic Poisson’s ratios determine why lamellipodia persistently evolve into sheet-like structures. Our predictions are confirmed by published experiments. The revealed self-adaptive elastic properties of the networks are also applicable to the endocytosis, phagocytosis, vesicle trafficking, intracellular pathogen transport and dendritic spine formation

    Summary of Thermo–Time Domain Reflectometry Method: Advances in Monitoring In Situ Soil Bulk Density

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    Soil bulk density (ρb) is a key indicator of soil compaction and soil health that relates to water infiltration, plant rooting depth, nutrient availability, and soil microbial activity. Under field conditions, ρb usually varies with time and depth because of agronomic practices, root growth, and environmental processes (e.g., rainfall events, wetting/drying, and freezing/thawing). The traditional technique (i.e., the coring method) for determining ρb has the problems of destructive sampling, labor intensive, and is unable to capture the spatial and temporal variations. In a chapter of the recent Methods of Soil Analysis book, we present a review of the theory, instrumentation, and procedures of the thermo–time domain reflectometry (thermo-TDR) technique for monitoring in situ ρb (Lu et al., 2017)

    BigDataBench: a Big Data Benchmark Suite from Internet Services

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    As architecture, systems, and data management communities pay greater attention to innovative big data systems and architectures, the pressure of benchmarking and evaluating these systems rises. Considering the broad use of big data systems, big data benchmarks must include diversity of data and workloads. Most of the state-of-the-art big data benchmarking efforts target evaluating specific types of applications or system software stacks, and hence they are not qualified for serving the purposes mentioned above. This paper presents our joint research efforts on this issue with several industrial partners. Our big data benchmark suite BigDataBench not only covers broad application scenarios, but also includes diverse and representative data sets. BigDataBench is publicly available from http://prof.ict.ac.cn/BigDataBench . Also, we comprehensively characterize 19 big data workloads included in BigDataBench with varying data inputs. On a typical state-of-practice processor, Intel Xeon E5645, we have the following observations: First, in comparison with the traditional benchmarks: including PARSEC, HPCC, and SPECCPU, big data applications have very low operation intensity; Second, the volume of data input has non-negligible impact on micro-architecture characteristics, which may impose challenges for simulation-based big data architecture research; Last but not least, corroborating the observations in CloudSuite and DCBench (which use smaller data inputs), we find that the numbers of L1 instruction cache misses per 1000 instructions of the big data applications are higher than in the traditional benchmarks; also, we find that L3 caches are effective for the big data applications, corroborating the observation in DCBench.Comment: 12 pages, 6 figures, The 20th IEEE International Symposium On High Performance Computer Architecture (HPCA-2014), February 15-19, 2014, Orlando, Florida, US

    Nitrogen addition strengthens the stabilizing effect of biodiversity on productivity by increasing plant trait diversity and species asynchrony in the artificial grassland communities

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    BACKGROUND AND AIMS: Nitrogen (N) enrichment usually weakens the stabilizing effect of biodiversity on productivity. However, previous studies focused on plant species richness and thus largely ignored the potential contributions of plant functional traits to stability, even though evidence is increasing that functional traits are stronger predictors than species richness of ecosystem functions. METHODS: We conducted a common garden experiment manipulating plant species richness and N addition levels to quantify effects of N addition on relations between species richness and functional trait identity and diversity underpinning the 'fast-slow' economics spectrum and community stability. RESULTS: Nitrogen addition had a minor effect on community stability but increased the positive effects of species richness on community stability. Increasing community stability was found in the species-rich communities dominated by fast species due to substantially increasing temporal mean productivity relative to its standard deviation. Furthermore, enhancement in 'fast-slow' functional diversity in species-rich communities dominated by fast species under N addition increased species asynchrony, resulting in a robust biodiversity-stability relationship under N addition the artificial grassland communities. CONCLUSION: The findings demonstrate mechanistic links between plant species richness, 'fast-slow' functional traits, and community stability under N addition, suggesting that dynamics of biodiversity-stability relations under global changes are the results of species-specific responses of 'fast-slow' traits on the plant economics spectrum

    A Novel Double Cluster and Principal Component Analysis-Based Optimization Method for the Orbit Design of Earth Observation Satellites

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    The weighted sum and genetic algorithm-based hybrid method (WSGA-based HM), which has been applied to multiobjective orbit optimizations, is negatively influenced by human factors through the artificial choice of the weight coefficients in weighted sum method and the slow convergence of GA. To address these two problems, a cluster and principal component analysis-based optimization method (CPC-based OM) is proposed, in which many candidate orbits are gradually randomly generated until the optimal orbit is obtained using a data mining method, that is, cluster analysis based on principal components. Then, the second cluster analysis of the orbital elements is introduced into CPC-based OM to improve the convergence, developing a novel double cluster and principal component analysis-based optimization method (DCPC-based OM). In DCPC-based OM, the cluster analysis based on principal components has the advantage of reducing the human influences, and the cluster analysis based on six orbital elements can reduce the search space to effectively accelerate convergence. The test results from a multiobjective numerical benchmark function and the orbit design results of an Earth observation satellite show that DCPC-based OM converges more efficiently than WSGA-based HM. And DCPC-based OM, to some degree, reduces the influence of human factors presented in WSGA-based HM

    Variations in growth traits and wood physicochemical properties among Pinus koraiensis families in Northeast China

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    This study aimed to explore and improve the different economic values of Pinus koraiensis (Siebold and Zucc.) by examining the variations in 6 growth traits and 9 physicochemical wood properties among 53 P. koraiensis half-sib families. Growth traits assessed included height, diameter at breast height, volume, degree of stem straightness, stem form, and branch number per node, while wood properties assessed included density, fiber length and width, fiber length to width ratio, and cellulose, hemicellulose, holocellulose, lignin, and ash contents. Except for degree of stem straightness and branch number per node, all other traits exhibited highly significant variations (P < 0.01) among families. The coefficients of variation ranged from 5.3 (stem form) to 66.7% (ash content), whereas, the heritability ranged from 0.136 (degree of stem straightness) to 0.962 (ash content). Significant correlations were observed among growth traits and wood physicochemical properties. Principal component analysis identified four distinct groups representing growth traits, wood chemical and physical properties, and stem form traits. Multi-trait comprehensive evaluation identified three groups of elite families based on breeding objectives, including rapid growth, improved timber production for building and furniture materials, and pulpwood production. These specific families should be used to establish new plantations

    High level soluble expression, one-step purification and characterization of HIV-1 p24 protein

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    <p>Abstract</p> <p>Background</p> <p>P24 protein is the major core protein of HIV virus particle and has been suggested as a specific target for antiviral strategies. Recombinant p24 protein with natural antigenic activity would be useful for various studies, such as diagnostic reagents and multi-component HIV vaccine development. The aim of this study was to express and purify the p24 protein in soluble form in <it>E.coli</it>.</p> <p>Results</p> <p>According to the sequence of the p24 gene, a pair of primers was designed, and the target sequence of 700 bp was amplified using PCR. The PCR product was cloned into pQE30 vector, generating the recombinant plasmid pQE30-p24. SDS-PAGE analysis showed that the His-tagged recombinant p24 protein was highly expressed in soluble form after induction in <it>E. coli </it>strain BL21. The recombinant protein was purified by nickel affinity chromatography and used to react with HIV infected sera. The results showed that the recombinant p24 protein could specifically react with the HIV infected sera. To study the immunogenicity of this soluble recombinant p24 protein, it was used to immunize mice for the preparation of polyclonal antibody. Subsequent ELISA and Western-Blot analysis demonstrated that the p24 protein had proper immunogenicity in inducing mice to produce HIV p24 specific antibodies.</p> <p>Conclusion</p> <p>In this work, we report the high level soluble expression of HIV-1 p24 protein in <it>E. coli</it>. This soluble recombinant p24 protein specifically react with HIV infected sera and elicit HIV p24 specific antibodies in mice, indicating this soluble recombinant p24 protein could be a promising reagent for HIV diagnosis.</p
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