Early Empirical Evidence for the Effects of Adaptive Ramp Metering on Measures of Travel Time Reliability

Adaptive ramp metering (ARM) is a critical component of smart freeway corridors under an active traffic management portfolio. While improving capacity through smart corridors and application of proactive traffic management solutions is less costly and easier to deploy than freeway widening, conversion to smart corridors still represents a sizable investment for a state department of transportation. Early evidence of improvements following these projects can be valuable to agencies. However, in the U.S. there have been limited evaluations, of smart corridors in general and ARM in particular, based on real operational data. This thesis explores travel time reliability measures for the eastbound (EB) Interstate 80 (I-80) corridor in the San Francisco Bay Area before and after implementation of ARM using INRIX data. These measures include buffer index, planning time, and measures from the literature that account for both skew and width of the travel time distribution. The measures are estimated for the entire corridor as well as corridor segments upstream of a bottleneck that historically have the worst measures of reliability. A new metric for measuring unreliability that may be derived from readily available INRIX data is also proposed in the thesis using data from the study corridor. While the ARM system is relatively new, the results indicate positive trends in measures of reliability even as the number of incidents on the corridor has increased in line with the national crash trends. The spatio-temporal trend evaluation framework used here may be used in the future to obtain more robust conclusions. However, since multiple smart corridor components were installed simultaneously, it may not be possible to fully isolate the effects of the ARM, or any of the other systems, individually

Successful completion of a cyclic ground test of a mercury ion auxiliary propulsion system

An engineering model Ion Auxiliary Propulsion System (IAPS) 8-cm thruster (S/N 905) has completed a life test at NASA Lewis Research Center. The mercury ion thruster successfully completed and exceeded the test goals of 2557 on/off cycles and 7057 hr of operation at full thrust. The final 1200 cycles and 3600 hr of the life test were conducted using an engineering model of the IAPS power electronics unit (PEU) and breadboard digital controller and interface unit (DCIU). This portion of the test is described in this paper with a charted history of thruster operating parameters and off-normal events. Performance and operating characteristics were constant throughout the test with only minor variations. The engineering model power electronics unit operated without malfunction; the flight software in the digital controller and interface unit was exercised and verified. Post-test inspection of the thruster revealed facility enhanced accelerator grid erosion but overall the thruster was in good condition. It was concluded that the thruster performance was not drastically degraded by time or cycles. Additional cyclic testing is currently under consideration

Francis Daniels Moore: one of the brightest minds in the surgical field.

Francis Daniels Moore was a pioneer ahead of his time who made numerous landmark contributions to the field of surgery, including the understanding of metabolic physiology during surgery, liver and kidney transplant, and the famous Study on Surgical Services of the United States (SOSSUS) report of 1975 that served for decades as a guideline for development of surgical residencies. He was the epitome of what a physician should be, a compassionate and dedicated surgeon, innovative scientist, and a medical professional dedicated to quality medical education across all specialties

Association of Epstein-Barr virus with nasopharyngeal carcinoma and current status of development of cancer-derived cell lines

It is well known that the Epstein-Barr virus (EBV) contributes directly to tumourigenesis in nasopharyngeal carcinoma (NPC), primarily in the undifferentiated form of NPC (WHO type III; UNPC or UC), which is commonly found in South East Asia. Unfortunately, research in NPC has been severely hampered by the lack of authentic EBV-positive (EBV+) human NPC cell lines for study. Since 1975, there have been more than 20 reported NPC cell lines. However, many of these NPC-derived cell lines do not express EBV transcripts in long-term culture, and therefore that finding may dispute the fundamental theory of NPC carcinogenesis. In fact, currently only one EBV+ human NPC cell line (C-666) in long-term culture has been reported. Hence, most of the NPC cell lines may not be representative of the disease itself. In order to better understand and treat NPC, there is an urgent need to develop more EBV+ human NPC cell lines. In this review, we discuss the authenticity of existing NPC cell lines and the impact of our understanding of NPC biology on the treatment of the disease and the relationship of EBV to NPC in the context of cell lines

Density, Velocity, and Magnetic Field Structure in Turbulent Molecular Cloud Models

We use 3D numerical MHD simulations to follow the evolution of cold, turbulent, gaseous systems with parameters representing GMC conditions. We study three cloud simulations with varying mean magnetic fields, but identical initial velocity fields. We show that turbulent energy is reduced by a factor two after 0.4-0.8 flow crossing times (2-4 Myr), and that the magnetically supercritical cloud models collapse after ~6 Myr, while the subcritical cloud does not collapse. We compare density, velocity, and magnetic field structure in three sets of snapshots with matched Mach numbers. The volume and column densities are both log-normally distributed, with mean volume density a factor 3-6 times the unperturbed value, but mean column density only a factor 1.1-1.4 times the unperturbed value. We use a binning algorithm to investigate the dependence of kinetic quantities on spatial scale for regions of column density contrast (ROCs). The average velocity dispersion for the ROCs is only weakly correlated with scale, similar to the mean size-linewidth relation for clumps within GMCs. ROCs are often superpositions of spatially unconnected regions that cannot easily be separated using velocity information; the same difficulty may affect observed GMC clumps. We analyze magnetic field structure, and show that in the high density regime, total magnetic field strengths increase with density with logarithmic slope 1/3 -2/3. Mean line-of-sight magnetic field strengths vary widely across a projected cloud, and do not correlate with column density. We compute simulated interstellar polarization maps at varying orientations, and determine that the Chandrasekhar-Fermi formula multiplied by a factor ~0.5 yields a good estimate of the plane-of sky magnetic field strength provided the dispersion in polarization angles is < 25 degrees.Comment: 56 pages, 25 figures; Ap.J., accepte

Computation of acoustic scattering from elastic conical shells with endcaps using the hybrid finite element/ virtual source approach

Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Ocean Engineering, 2004.Includes bibliographical references (p. 101-102).Studying and understanding acoustic scattering pattern from underwater targets has been of interest to various communities such as the archeologists and the navy for several reasons and applications. The present state-of-the-art technique in this area involves such methods as analytical approach and FEM/BEM numerical technique. This thesis aims to study and demonstrate the power of using the hybrid virtual source/FE approach where the physical presence of a target is replaced by virtual sources placed in the vicinity of the target and in a manner where the pressure/displacement relationship on the target surface is satisfied by the virtual sources when the target is being insonified. Accurate results for the far-field radiation of the target can be obtained by superposition of the point source Green's function of each virtual source. The hybrid virtual source/FE approach shows potential to be a computationally efficient method for computing acoustic scattering. The derivation of the dynamic flexibility matrix for an elastic conical shell with endcaps will be illustrated in this thesis. It will be shown that the dynamic flexibility matrix corresponds to the acoustic admittance matrix in the virtual source approach where the scattering functions are computed in the MIT's program OASES/SCATT.(cont.) Moreover, the benchmarking and validation of the approach will be conducted with the hybrid analytical/ virtual source approach. Firstly, the approach predicts natural frequencies close to the theoretical analysis for higher order modes with more than 2 circumferential transverse vibration lobes. Secondly, it produces displacement profile that conforms to analytical results. The scattering functions are also in agreement those computed by the hybrid analytical/ virtual source approach, with discrepancies observed at lower frequencies. In exact terms, discrepancies start to appear for frequency in the range of 1000 to 2000 Hz for a 0.01m thick, 2 m long, 0.3m radius steel cylinder without endcaps. The scattering functions will be compared with the SCATT/OASES virtual source approach for pressure release and rigid cylinders and cones. For the hybrid FE/virtual source approach, the structural sound speed and density approach zero and infinity for pressure-release and rigid target respectively. On the other hand, in the SCATT/OASES virtual source approach, the pressure and displacement are required to vanish on the target surface respectively. It will be shown that the two approaches agree with each other.(cont.) Moreover, scattering functions over steel cones and cylinders for various frequencies have also been derived in this research. The results will be interpreted physically and theoretically in this thesis. The importance of including structural damping in the finite element formulation of the target so as to reflect the effect of resonance on scattering will be illustrated. Other issues, such as effect of target orientations on scattering, will also be investigated in this thesis. The code has shown good potential for adaptation to compute scattering over other axisymmteric shapes using conical shells and circular plates as building blocks and the hybrid FE/ virtual source approach.by Hwee Min Charles Low.S.M

Inheritance of single copy nuclear genes (SCNGs) in artificial hybrids of Hesperocyparis arizonica x H. macrocarpa: Potential for utilization in the detection of hybridization in natural populations

Analyses were performed on 18 artificial hybrids from a cross of Hesperocyparis arizonica (male parent) x H. macrocarpa (female parent) using 9 single copy nuclear genes (SCNGs). Three SCNG were found to be informative: myb, 4CL and CnAIB2. Gene myb contained 5 variable sites, of which site 89 was homozygous (CC, TT) as was site 261 (GG, AA) and useful for the detection of hybridization. All 18 hybrids were heterozygous (CT and GA) at these 2 sites as predicted in hybrids. 4CL contained 8 variable sites, of which 1 site (591) was homozygous (TT, CC) and all 18 hybrids were heterozygous (TC) at this site as expected. CnAIP2 had two variable sites: 301 (AA, AC) and 554 (AG, AA). For site 301, 8 hybrids were AA, and 10 were AC as expected. For site 554, 10 hybrids were AA and 8 were AG, so neither would be useful for unequivocally identifying hybrids. The inheritance of variable sites for the three SCNGs followed simple co-occurrence. Examination of myb in the 18 hybrids revealed 2 cases of cross-over in the pollen gametes