844 research outputs found
Study on the MAO-A and MAO-B inhibitory properties of a series of new coumarin derivatives for the treatment of Parkinson's disease
Traballo fin de mestrado (UDC.CIE). Neurociencia. Curso 2015/201
Applying Joint Modelling Regression Approaches in Biomedical Data Science
In recent years, the technological revolution is allowing the collection of an
enormous amount of data of different types, creating enormously complex databases that require the collaboration
of statisticians and clinicians to carry out a biomedical study with guarantees, applying the tools of data science.
This requires the development of new statistical techniques. This thesis focuses on joint modelling regression
models for multivariate responses. Specifically, we study the cases of two and three continuous outcomes, as well
as models for longitudinal and survival data. These techniques are applied in three studies of major epidemiological
importance: liver damage and survival in COVID-19 patients, perinatal mental health during the COVID-19
pandemic, and the study of thyroid-related hormones
The geometry of modified Riemannian extensions
We show that every paracomplex space form is locally isometric to a modified
Riemannian extension and give necessary and sufficient conditions so that a
modified Riemannian extension is Einstein. We exhibit Riemannian extension
Osserman manifolds of signature (3,3) whose Jacobi operators have non-trivial
Jordan normal form and which are not nilpotent. We present new four dimensional
results in Osserman geometry
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