114 research outputs found
Martin Chemnitz and his Locus DE SACRA SCRIPTURA Against Roman Errors
This paper bas been written with the intention of giving credit to whom it is due. The value of the work of Chemnitz will be shown in an account of his life and in an analysis of the first locus of his most important work, the Examen Concilii Tridentini
Lutheran Principles in Government
Any theory that overlooks the hand of God in government is untenable. The same is true of any of the acceptable theories, if they are viewed as excluding the consideration of God. A contract between men, for example, can never overlook the aim of God. We must remember, however, that though civil government is ordained by God, it did not come immediately from Him, but came, in one manner or another, through the people
Semantic Road Detection for Non-Ideal Rural Roadways with Limited Apriori Maps
In this work we provide a system that has the ability to detect the entire road area ahead and provide semantic information about where to move within that area for an autonomous vehicle on a wide array of road types in rural environments. This approach combines current state of the art image road segmentation, image lane detection and lidar ground segmentation techniques by fusing the output of algorithms based on these techniques to produce a costmap to be used by a local planner for motion planning and vehicle control.
One of the main goals of this thesis was to prove whether this is a sensible task given the current state of the art in the relevant algorithms and computational resources, and to propose improvements that address the limitations of this work. These limitations were determined by applying the proposed system to the real-world driving scenarios in simulation and by evaluation on a test vehicle driven on real public rural roadways.
We have presented a functional system that works within the assumptions and limitations set, and shows higher accuracy results compared to the traditional approach
Outils de TAO – Mettons-les au diapason
Il arrive trop souvent que les traducteurs se laissent collectivement emporter par une vague de panique, tout comme la foule traumatisée à l’idée de perdre une dizaine de jours lors du passage du calendrier julien au calendrier grégorien. Il s’agit dans la plupart des cas de « beaucoup de bruit pour rien », le « rien » en question prenant de nos jours la forme de portails de traduction via internet, d’externalisation ouverte (crowd-sourcing), de traduction automatique et d’absence de normes m..
Serum Levels of the Adipokine FGF21 Depend on Renal Function
OBJECTIVE—To investigate renal elimination of the adipokine fibroblast growth factor 21 (FGF21) by determining circulating FGF21 levels in patients on chronic hemodialysis (CD) as compared with control subjects with a glomerular filtration rate (GFR) >50 ml/min
IMRT and carbon ion boost for malignant salivary gland tumors: interim analysis of the COSMIC trial
BACKGROUND: The COSMIC trial is designed to evaluate toxicity in dose-escalated treatment with intensity-modulated radiotherapy (IMRT) and carbon ion boost for malignant salivary gland tumors (MSGT) of the head and neck including patients with inoperable/ incompletely resected MSGTs (R2-group) and completely resected tumors plus involved margins or perineural spread (R1-group). METHODS: COSMIC is a prospective phase II trial of IMRT (25 × 2 Gy) and carbon ion boost (8 × 3 GyE). Primary endpoint is mucositis CTC°III, secondary endpoints are local control, progression-free survival, and toxicity. Evaluation of disease response is carried out according to the Response Evaluation Criteria in Solid Tumors (RECIST); toxicity is assessed using NCI CTC v 3.0. RESULTS: Twenty-nine patients were recruited from 07/2010 to 04/2011, all patients have at least completed first follow-up. Sixteen patients were treated in the R2-group, 13 in the R1-group. All treatments were completed as planned and well tolerated, mucositis CTC grade III was 25% (R2) and 15.4% (R1), no dysphagia CTC grade III was observed, no feeding tubes were necessary. Side-effects rapidly resolved, only 4 patients (13.8%) reported xerostomia grade II at first follow-up. Overall response rate (complete and partial response) according to RECIST in the R2-group is 68.8% at 6–8 weeks post treatment, all patients within this group showed radiological signs of treatment response. CONCLUSION: No unexpected toxicity was observed, mucositis rates and other side effects do not differ between patients with visible residual tumor and macroscopically completely resected tumors. Initial treatment response is promising though longer follow-up is needed to assess local control. TRIAL REGISTRATION: Clinical trial identifier NCT 0115427
Toward a hyperventilation detection system in freediving: a proof of concept using force sensor technology
Background and aimHyperventilation before breath-hold diving (freediving) is widely accepted as a risk factor for hypoxic syncope or blackout (BO), but there is no practical way to address it before dives. This study explores the feasibility of using a force sensor to predict end-tidal carbon dioxide (PETCO2) to assess hyperventilation in freedivers.Methods and resultsTwenty-one freedivers volunteered to participate during two national competitions. The divers were instructed to breathe normally and perform three dry apneas of 1, 2, and 3-min duration at 2-min intervals in a sitting position. Before and after the apneas, PETCO2 was recorded. The signal from the force sensor, attached to a chest belt, was used to record the frequency and amplitude of the chest movements, and the product of these values in the 60 s before the apnea was used to predict PETCO2. The mean PETCO2 was below 35 mmHg before all apneas. The mean amplitude of the signal from the force sensor increased from apnea 1 to apnea 3 (p < 0.001), while the respiratory rate was similar (NS). The product of the respiratory rate and amplitude from the force sensor explained 34% of the variability of the PETCO2 in the third apnea.ConclusionThis study shows that a force sensor can estimate hyperventilation before static apnea, providing a basis for further research. More studies are needed to confirm its effectiveness in preventing issues. Freedivers may hyperventilate without noticing it, and such a system could improve awareness of this condition. Additional underwater tests are essential to determine whether this system can enhance safety in freediving
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Buckling Pneumatic Linear Actuators Inspired by Muscle
The mechanical features of biological muscles are difficult to reproduce completely in synthetic systems. A new class of soft pneumatic structures (vacuum-actuated muscle-inspired pneumatic structures) is described that combines actuation by negative pressure (vacuum), with cooperative buckling of beams fabricated in a slab of elastomer, to achieve motion and demonstrate many features that are similar to that of mammalian muscle.Chemistry and Chemical Biolog
Metabolic loss of deuterium from isotopically labeled glucose
The isotopically substituted molecule (6- 13 C, 1, 6, 6- 2 H 3 )glucose was evaluated to determine whether metabolic 2 H loss would prevent its use in quantitating pentose phosphate pathway (PPP) activity. PPP activity causes the C1 of glucose to be lost as CO 2 , while C6 can appear in lactate. 2 H NMR analysis of the lactate produced from this glucose can distinguish (3- 2 H)-lactate (from C1 of glucose) from (3- 13 C, 3, 3- 2 H Z )lactate (from C6 of glucose). 2 H NMR spectroscopic analysis of medium containing (4- 13 C, 1,6,6 −2 H 3 ) glucose after incubation with cultured rat 9L glioma cells suggested a 30.8 ± 2.1% PPP activity as compared with 6.0 ± 0.8% from separate, parallel incubations with (1- 13 C)glucose and (6- 13 C)glucose. Subsequent experiments with other isotopically labeled glucose molecules suggest that this discrepancy is due to selective loss of 2 H from the C1 position of glucose, catalyzed by phosphoman-nose isomerase. Failure to consider 2 H exchange from the C1 and C6 positions of glucose can lead to incorrect conclusions in metabolic studies utilizing this and other deuterated or tritiated glucose molecules.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/38491/1/1910320317_ftp.pd
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