3,505 research outputs found
Refining Superpages and Forward-Error Correction
The electrical engineering solution to lambda calculus is defined not only by the deployment of multi-processors, but also by the key need for Scheme [16]. In this paper, we show the synthesis of the transistor, which embodies the practical principles of theory. In order to solve this issue, we argue not only that IPv6 and replication are rarely incompatible, but that the same is true for hierarchical databases
The relevance of biotechnology in the development of functional foods for improved nutritional and health quality in developing countries
The quality of food and food plants can be modified and optimized to meet the nutritional and health needs of at-risk and compromised populations prevalent in most of the developing countries. High rates of malnutrition, infectious disease as well as diet-related diseases such as diabetes and hypertension are prevalent in many developing countries. These are as a result of compromised immune function, inadequate sources of nutritious and quality foods and limited access to healthy and suitable foods. Biotechnology and genetic modification techniques have been proposed and applied for the improvement of the quality of various food crops. These have typically been geared towards increasing yields and pest resistance of cash crops. There is considerably less emphasis however, toward improving quality with regard to fortification or functionality of foods and food plants. Functional foods have nutritional and physiological benefits and are applicable in disease prevention and management. The application of biotechnology techniques for the development of functional food plants with higher levels of bioactive components or increased availability of nutrients would greatly benefit most populations in developing countries and improve the health and nutritional status overall.
Key words: Biotechnology, functional foods, food quality, health, developing countries.
African Journal of Biotechnology Vol. 2 (12), pp. 631-635, December 200
Gene Therapy for Cardiovascular Disease
The last decade has seen substantial advances in the development of gene therapy strategies and vector technology for the treatment of a diverse number of diseases, with a view to translating the successes observed in animal models into the clinic. Perhaps the overwhelming drive for the increase in vascular gene transfer studies is the current lack of successful long-term pharmacological treatments for complex cardiovascular diseases. The increase in cardiovascular disease to epidemic proportions has also led many to conclude that drug therapy may have reached a plateau in its efficacy and that gene therapy may represent a realistic solution to a long-term problem. Here, we discuss gene delivery approaches and target diseases
Jajak Pendapat Timor Timur Dalam Perspektif Perlindungan Hukum Masyarakat Sipil Pasca Konvensi Jenewa 1949
This study aims to determine the dedermination of East Timor in the perspective of the legal protection of civilians after the Geneva Convention of 1949. This study is a normative law. The method used is the approach Statute and Conceptual approach. Results of the study found that First , there is no post- Civil Legal Protection East Timor According to the 1949 Geneva Convention (IV Geneva Convention Concerning the Protection of Civilian Persons in war) . Second , the Indonesian government be held accountable law violations against the self determination of East Timor in 199
Impact of tropical forest disturbance and conversion on insect diversity in Costa Rica, Central America
Inhibition of pancreatic cholesterol esterase reduces cholesterol absorption in the hamster
BACKGROUND: Pancreatic cholesterol esterase has three proposed functions in the intestine: 1) to control the bioavailability of cholesterol from dietary cholesterol esters; 2) to contribute to incorporation of cholesterol into mixed micelles; and 3) to aid in transport of free cholesterol to the enterocyte. Inhibitors of cholesterol esterase are anticipated to limit the absorption of dietary cholesterol. RESULTS: The selective and potent cholesterol esterase inhibitor 6-chloro-3-(1-ethyl-2-cyclohexyl)-2-pyrone (figure 1, structure 1) was administered to hamsters fed a high cholesterol diet supplemented with radiolabeled cholesterol ester. Hamsters were gavage fed (3)H-labeled cholesteryl oleate along with inhibitor 1, 0–200 micromoles. Twenty-four hours later, hepatic and serum radioactive cholesterol levels were determined. The ED(50 )of inhibitor 1 for prevention of the uptake of labeled cholesterol derived from hydrolysis of labeled cholesteryl oleate was 100 micromoles. The toxicity of inhibitor 1 was investigated in a 30 day feeding trial. Inhibitor 1, 100 micromoles or 200 micromoles per day, was added to chow supplemented with 1% cholesterol and 0.5% cholic acid. Clinical chemistry urinalysis and tissue histopathology were obtained. No toxicity differences were noted between control and inhibitor supplemented groups. CONCLUSIONS: Inhibitors of cholesterol esterase may be useful therapeutics for limiting cholesterol absorption
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Language-related domain-specific and domain-general systems in the human brain.
While a long history of neuropsychological research places language function within a primarily left-lateralized frontotemporal system, recent neuroimaging work has extended this language network to include a number of regions traditionally thought of as 'domain-general'. These include dorsal frontal, parietal, and medial temporal lobe regions known to underpin cognitive functions such as attention and memory. In this paper, we argue that these domain-general systems are not required for language processing and are instead an artefact of the tasks typically used to study language. Recent work from our lab shows that when syntactic processing - arguably the only domain-specific language function - is measured in a task-free, naturalistic manner, only the left-lateralized frontotemporal syntax system and auditory network are activated. When syntax is measured within the context of a task, several other domain-general networks come online and are functionally connected to the frontotemporal system. While we have long argued that syntactic processing does not occur in isolation but is processed in parallel with semantics and pragmatics - functions of the wider language system - our recent work makes a strong case for the domain-specificity of the frontotemporal syntax system and its autonomy from domain-general networks
A Qualitative Study of Role Transition from RN to APN
Role transition from registered nurse to advanced practice nurse is a difficult process. A qualitative thematic analysis guided the integration of various experiences of 24 students in a twocredit, web-based role development course in a Master’s of Science in Nursing program at a large Midwestern university. Findings supported that students had developed an understanding of the core competencies and complexity of the advanced practice nurse role, and that beginning role transition had occurred. An overarching theme, ‘the essence of nursing’ was evident. Three subthemes supported the occurrence of role transition, which included the importance of: a) building a framework for nursing practice, b) direct patient care, and c) comprehension and exemplification of professional responsibilities. This study has implications for nurse educators interested in promoting advanced practice nurse role transition early in the educational process
The Learning of Liberty
American schools are in a state of crisis.At the root of our current perplexity, beneath the difficulties with funding, social problems, and low test scores, festers a serious uncertainty as to what the focus and goals of education should be. We are increasingly haunted by the suspicion that our educational theories and institutions have lost sight of the need to perpetuate a core of moral and civic knowledge that is essential for any citizen's education, and indeed for any individual's happiness. Mining the Founders' rich reflections on education, the Pangles suggest, can help us recover a clearer sense of perspective and purpose.With a commanding knowledge of the history of political philosophy, the authors illustrate how the Founders both drew upon and transformed the ideas of earlier philosophers of education such as Plato, Xenophon, Milton, Bacon, and Locke. They trace the emergence of a new American ideal of public education that puts civic instruction at its core to sustain a high quality of leadership and public discourse while producing resourceful, selfreliant members of a uniquely fluid society. The Pangles also explore the wisdom and the weaknesses inherent in Jefferson's attempt to create a comprehensive system of schooling that would educate parents and children and offer unprecedented freedom of choice to university students. An original closing section examines the Founders' ideas for bringing all aspects of society to bear on education. It also shows how Washington, Jefferson, and Franklin presented their own lives as models for the education of others and analyzes the subtle, provocative moral philosophy implicit in the selfdepiction of each.The Learning of Liberty is historical and scholarly yet relentlessly practical, seeking from the Founders useful insights into the human soul and the character of good education. Even if the Founders do not provide us with readymade solutions to many of our problems, the Pangles suggest, a study of their writings can give us a more realistic perspective, by teaching that our bewilderment is in some measure an outgrowth of unresolved tensions embedded in the Founders' own conceptions of republicanism, religion, education, and human nature
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The Influence of Mindfulness During the Travel Anticipation Phase on Search and Choice Behaviors, Search and Choice Outcomes, and Trip Evaluations
Tourists exhibit varying levels of mindfulness during the travel anticipation phase, when they are engaged in vacation planning (Clawson & Knetsch, 1966). Mindfulness is associated with analytic decision making through a heightened sensitivity to one’s environment and openness to new information (Langer & Moldoveanu, 2000). This study considered the influence that mindfulness during the travel anticipation phase has on: search and choice behaviors (planning horizon, size of the choice set, information source variety), search and choice outcomes (planning enjoyment, confidence in destination choice), and trip evaluations (satisfaction, behavioral loyalty, attitudinal loyalty). Additional analysis was conducted for mediating and moderating effects based on how much of the trip was planned in advance, whether the tourist visited a repeat or new destination, and whether the tourist considered the area to be their primary destination. The results of the study confirmed that mindfulness during the anticipation phase influenced the travel experience
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