Measuring the Galactic Cosmic Ray Flux with the LISA Pathfinder Radiation Monitor

Test mass charging caused by cosmic rays will be a significant source of acceleration noise for space-based gravitational wave detectors like LISA. Operating between December 2015 and July 2017, the technology demonstration mission LISA Pathfinder included a bespoke monitor to help characterise the relationship between test mass charging and the local radiation environment. The radiation monitor made in situ measurements of the cosmic ray flux while also providing information about its energy spectrum. We describe the monitor and present measurements which show a gradual 40% increase in count rate coinciding with the declining phase of the solar cycle. Modulations of up to 10% were also observed with periods of 13 and 26 days that are associated with co-rotating interaction regions and heliospheric current sheet crossings. These variations in the flux above the monitor detection threshold (approximately 70 MeV) are shown to be coherent with measurements made by the IREM monitor on-board the Earth orbiting INTEGRAL spacecraft. Finally we use the measured deposited energy spectra, in combination with a GEANT4 model, to estimate the galactic cosmic ray differential energy spectrum over the course of the mission

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1.

In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field. Our knowledge base and relevant new technologies have also been expanding. Thus, it is important to formulate on a regular basis updated guidelines for monitoring autophagy in different organisms. Despite numerous reviews, there continues to be confusion regarding acceptable methods to evaluate autophagy, especially in multicellular eukaryotes. Here, we present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes. These guidelines are not meant to be a dogmatic set of rules, because the appropriateness of any assay largely depends on the question being asked and the system being used. Moreover, no individual assay is perfect for every situation, calling for the use of multiple techniques to properly monitor autophagy in each experimental setting. Finally, several core components of the autophagy machinery have been implicated in distinct autophagic processes (canonical and noncanonical autophagy), implying that genetic approaches to block autophagy should rely on targeting two or more autophagy-related genes that ideally participate in distinct steps of the pathway. Along similar lines, because multiple proteins involved in autophagy also regulate other cellular pathways including apoptosis, not all of them can be used as a specific marker for bona fide autophagic responses. Here, we critically discuss current methods of assessing autophagy and the information they can, or cannot, provide. Our ultimate goal is to encourage intellectual and technical innovation in the field

LISA pathfinder performance confirmed in an open-loop configuration: results from the free-fall actuation mode

We report on the results of the LISA Pathfinder (LPF) free-fall mode experiment, in which the control force needed to compensate the quasistatic differential force acting on two test masses is applied intermittently as a series of “impulse” forces lasting a few seconds and separated by roughly 350 s periods of true free fall. This represents an alternative to the normal LPF mode of operation in which this balancing force is applied continuously, with the advantage that the acceleration noise during free fall is measured in the absence of the actuation force, thus eliminating associated noise and force calibration errors. The differential acceleration noise measurement presented here with the free-fall mode agrees with noise measured with the continuous actuation scheme, representing an important and independent confirmation of the LPF result. An additional measurement with larger actuation forces also shows that the technique can be used to eliminate actuation noise when this is a dominant factor

LISA Pathfinder platform stability and drag-free performance

The science operations of the LISA Pathfinder mission have demonstrated the feasibility of sub-femto-g free fall of macroscopic test masses necessary to build a gravitational wave observatory in space such as LISA. While the main focus of interest, i.e., the optical axis or the x-axis, has been extensively studied, it is also of great importance to evaluate the stability of the spacecraft with respect to all the other degrees of freedom (d.o.f.). The current paper is dedicated to such a study: the exhaustive and quantitative evaluation of the imperfections and dynamical effects that impact the stability with respect to its local geodesic. A model of the complete closed-loop system provides a comprehensive understanding of each component of the in-loop coordinates spectral density. As will be presented, this model gives very good agreement with LISA Pathfinder flight data. It allows one to identify the noise source at the origin and the physical phenomena underlying the couplings. From this, the stability performance of the spacecraft with respect to its geodesic is extracted as a function of frequency. Close to 1 mHz, the stability of the spacecraft on the XSC, YSC and ZSC d.o.f. is shown to be of the order of 5.0×10−15  m s−2 Hz−1/2 for X, 6.0×10−14  m s−2 Hz−1/2 for Y, and 4.0×10−14  m s−2 Hz−1/2 for Z. For the angular d.o.f., the values are of the order of 3×10−12  rad s−2  Hz−1/2 for ΘSC, 5×10−13  rad s−2  Hz−1/2 for HSC, and 3×10−13  rad s−2  Hz−1/2 for ΦSC. Below 1 mHz, however, the stability performances are worsened significantly by the effect of the star tracker noise on the closed-loop system. It is worth noting that LISA is expected to be spared from such concerns, as differential wave-front sensing, an attitude sensor system of much higher precision, will be utilized for attitude control

Forbush Decreases and < 2 Day GCR Flux Non-recurrent Variations Studied with LISA Pathfinder

Non-recurrent short-term variations of the galactic cosmic-ray (GCR) flux above 70 MeV n−1 were observed between 2016 February 18 and 2017 July 3 on board the European Space Agency LISA Pathfinder (LPF) mission orbiting around the Lagrange point L1 at 1.5 × 106 km from Earth. The energy dependence of three Forbush decreases is studied and reported here. A comparison of these observations with others carried out in space down to the energy of a few tens of MeV n−1 shows that the same GCR flux parameterization applies to events of different intensity during the main phase. FD observations in L1 with LPF and geomagnetic storm occurrence are also presented. Finally, the characteristics of GCR flux non-recurrent variations (peaks and depressions) of duration <2 days and their association with interplanetary structures are investigated. It is found that, most likely, plasma compression regions between subsequent corotating high-speed streams cause peaks, while heliospheric current sheet crossing causes the majority of the depressions

Spacecraft and interplanetary contributions to the magnetic environment on-board LISA Pathfinder

LISA Pathfinder (LPF) has been a space-based mission designed to test new technologies that will be required for a gravitational wave observatory in space. Magnetically driven forces play a key role in the instrument sensitivity in the low-frequency regime (mHz and below), the measurement band of interest for a space-based observatory. The magnetic field can couple to the magnetic susceptibility and remanent magnetic moment from the test masses and disturb them from their geodesic movement. LPF carried on-board a dedicated magnetic measurement subsystem with noise levels of 10 nT Hz−1/2 from 1 Hz down to 1 mHz. In this paper we report on the magnetic measurements throughout LPF operations. We characterize the magnetic environment within the spacecraft, study the time evolution of the magnetic field and its stability down to 20 μHz, where we measure values around 200 nT Hz−1/2⁠, and identify two different frequency regimes, one related to the interplanetary magnetic field and the other to the magnetic field originating inside the spacecraft. Finally, we characterize the non-stationary component of the fluctuations of the magnetic field below the mHz and relate them to the dynamics of the solar wind