7,189 research outputs found
Validity of a Clinical Scale in Predicting the Failure of Non-Invasive Ventilation in Hypoxemic Patients
Introduction: The HACOR scale is a clinical score that can predict early failure of NIV in hypoxemic acute respiratory failure (ARF) The aim of this study is to analyze the validity of the HACOR scale.
Methods: A retrospective study of a cohort of over 2749 episodes on 2711 consecutive patients requiring NIV for hypoxemic ARF in a polyvalent intensive care unit. The scale was measured before starting NIV and at 1, 6, 12, 24 and 48 h after the initiation of NIV.
Results: NIV failure occurred in 963 patients (35%). The value of the HACOR scale before NIV did not differ between success and failure. However, at 1, 6, 12, 24 and 48 h of NIV, the scale values clearly differed between the two groups. The HACOR scale at NIV initiation accurately predicts NIV failure in the first hour, with an optimal cut-off value of 8 points. The AUC for predicting NIV failure with HACOR at 1 h is greater than 0.9 in patients with pneumonia and adult respiratory distress syndrome (ARDS).
Conclusions: The HACOR scale measured at 1 h after NIV initiation accurately predicts NIV failure, especially in pneumonia and ARDS.info:eu-repo/semantics/publishedVersio
Preventing and addressing the stress reactions of health care workers caring for patients with COVID-19: Development of a digital platform (Be + against COVID)
Background: COVID-19 became a major public health concern in March 2020. Due to the high rate of hospitalizations for COVID-19 in a short time, health care workers and other involved staff are subjected to a large workload and high emotional distress.
Objective: The objective of this study is to develop a digital tool to provide support resources that might prevent and consider acute stress reactions in health care workers and other support staff due to the COVID-19 pandemic.
Methods: The contents of the digital platform were created through an evidence-based review and consensus conference. The website was built using the Google Blogger tool. The Android version of the app was developed in the Java and XML languages using Android Studio version 3.6, and the iOS version was developed in the Swift language using Xcode version 11.5. The app was evaluated externally by the Andalusian Agency for Healthcare Quality.
Results: We detected the needs and pressing situations of frontline health care workers, and then, we proposed a serial of recommendations and support resources to address them. These resources were redesigned using the feedback received. A website in three different languages (Spanish, English, and Portuguese) and a mobile app were developed with these contents, and the AppSaludable Quality Seal was granted to the app. A specific self-report scale to measure acute stress and additional tools were included to support the health care workforce. This instrument has been used in several Latin American countries and has been adapted considering cultural differences. The resources section of the website was the most visited with 18, 516 out of 68, 913 (26.9%) visits, and the “Self-Report Acute Stress Scale” was the most visited resource with 6468 out of 18, 516 (34.9%) visits.
Conclusions: The Be + against COVID platform (website and app) was developed and launched to offer a pool of recommendations and support resources, which were specifically designed to protect the psychological well-being and the work morale of health care workers. This is an original initiative different from the usual psychological assistance hotlines
Inverse Association between Dietary Iron Intake and Gastric Cancer: A Pooled Analysis of Case‐Control Studies of the Stop Consortium
Background: Inconsistent findings have been reported regarding the relationship between dietary iron intake and the risk of gastric cancer (GC). Methods: We pooled data from 11 case‐control studies from the Stomach Cancer Pooling (StoP) Project. Total dietary iron intake was derived from food frequency questionnaires combined with national nutritional tables. We derived the odds ratios (ORs) and 95% confidence intervals (CIs) for quartiles of dietary iron through multivariable unconditional logistic regression models. Secondary analyses stratified by sex, smoking status, caloric intake, anatomical subsite and histological type were performed. Results: Among 4658 cases and 12247 controls, dietary iron intake was inversely associated with GC (per quartile OR 0.88; 95% CI: 0.83–0.93). Results were similar between cardia (OR = 0.85, 95% CI = 0.77–0.94) and non‐cardia GC (OR = 0.87, 95% CI = 0.81–0.94), and for diffuse (OR = 0.79, 95% CI = 0.69–0.89) and intestinal type (OR = 0.88, 95% CI = 0.79–0.98). Iron intake exerted an independent effect from that of smoking and salt intake. Additional adjustment by meat and fruit/vegetable intake did not alter the results. Conclusions: Dietary iron is inversely related to GC, with no difference by subsite or histological type. While the results should be interpreted with caution, they provide evidence against a direct effect of iron in gastric carcinogenesis
A Non-parametric Approach to Measuring the \kpi{} Amplitudes in \dpkkpi{} Decay
Using a large sample of \dpkkpi{} decays collected by the FOCUS
photoproduction experiment at Fermilab, we present the first non-parametric
analysis of the \kpi{} amplitudes in \dpkkpi{} decay. The technique is similar
to the technique used for our non-parametric measurements of the \krzmndk{}
form factors. Although these results are in rough agreement with those of E687,
we observe a wider S-wave contribution for the \ksw{} contribution than the
standard, PDG \cite{pdg} Breit-Wigner parameterization. We have some weaker
evidence for the existence of a new, D-wave component at low values of the mass.Comment: 13 pages 3 figure
A Study of D0 --> K0(S) K0(S) X Decay Channels
Using data from the FOCUS experiment (FNAL-E831), we report on the decay of
mesons into final states containing more than one . We present
evidence for two Cabibbo favored decay modes, and
, and measure their combined branching fraction
relative to to be = 0.0106
0.0019 0.0010. Further, we report new measurements of
=
0.0179 0.0027 0.0026, = 0.0144 0.0032 0.0016,
and = 0.0208 0.0035 0.0021 where the first error is
statistical and the second is systematic.Comment: 11 pages, 3 figures, typos correcte
Study of Cabibbo Suppressed Decays of the Ds Charmed-Strange Meson involving a KS
We study the decay of Ds meson into final states involving a Ks and report
the discovery of Cabibbo suppressed decay modes Ds -> Kspi-pi+pi+ (179 +/- 36
events) and Ds -> Kspi+ (113 +/-26 events). The branching ratios for the new
modes are Gamma(Ds -> Kspi-pi+pi+)/Gamma(Ds -> KsK-pi+pi+) = 0.18 +/- 0.04 +/-
0.05 and Gamma(Ds -> Kspi+)/Gamma(Ds -> KsK+) = 0.104 +/- 0.024 +/- 0.013.Comment: 11 pages, 6 figure
The S-wave from the decay
Using data from FOCUS (E831) experiment at Fermilab, we present a model
independent partial-wave analysis of the S-wave amplitude from the
decay . The S-wave is a generic complex function to be
determined directly from the data fit. The P- and D-waves are parameterized by
a sum of Breit-Wigner amplitudes. The measurement of the S-wave amplitude
covers the whole elastic range of the system.Comment: 13 pages, 9 figures, submitted to Physics Letters
Search for and Using Genetic Programming Event Selection
We apply a genetic programming technique to search for the double Cabibbo
suppressed decays and .
We normalize these decays to their Cabibbo favored partners and find
\Lambda_c^+ \to p K^+ \pi^-\Lambda_c^+ \to p K^-
\pi^+ and D_s^+ \to K^+ K^+
\pi^-D_s^+ \to K^+ K^- \pi^+ where
the first errors are statistical and the second are systematic. Expressed as
90% confidence levels (CL), we find and respectively.
This is the first successful use of genetic programming in a high energy
physics data analysis.Comment: 10 page
Measurement of the D+ and Ds+ decays into K+K-K+
We present the first clear observation of the doubly Cabibbo suppressed decay
D+ --> K-K+K+ and the first observation of the singly Cabibbo suppressed decay
Ds+ --> K-K+K+. These signals have been obtained by analyzing the high
statistics sample of photoproduced charm particles of the FOCUS(E831)
experiment at Fermilab. We measure the following relative branching ratios:
Gamma(D+ --> K-K+K+)/Gamma(D+ --> K-pi+pi+) = (9.49 +/- 2.17(statistical) +/-
0.22(systematic))x10^-4 and Gamma(Ds+ --> K-K+K+)/Gamma(Ds+ --> K-K+pi+) =
(8.95 +/- 2.12(statistical) +2.24(syst.) -2.31(syst.))x10^-3.Comment: 10 pages, 8 figure
A Non-parametric Approach to the D+ to K*0bar mu+ nu Form Factors
Using a large sample of D+ -> K- pi+ mu+ nu decays collected by the FOCUS
photoproduction experiment at Fermilab, we present the first measurements of
the helicity basis form factors free from the assumption of spectroscopic pole
dominance. We also present the first information on the form factor that
controls the s-wave interference discussed in a previous paper by the FOCUS
collaboration. We find reasonable agreement with the usual assumption of
spectroscopic pole dominance and measured form factor ratios.Comment: 14 pages, 5 figures, and 2 tables. We updated the previous version by
changing some words, removing one plot, and adding two tables. These changes
are mostly stylisti
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