18,038 research outputs found
Effective response theory for zero energy Majorana bound states in three spatial dimensions
We propose a gravitational response theory for point defects (hedgehogs)
binding Majorana zero modes in (3+1)-dimensional superconductors. Starting in
4+1 dimensions, where the point defect is extended into a line, a coupling of
the bulk defect texture with the gravitational field is introduced.
Diffeomorphism invariance then leads to an Kac-Moody current running
along the defect line. The Kac-Moody algebra accounts for the
non-Abelian nature of the zero modes in 3+1 dimensions. It is then shown to
also encode the angular momentum density which permeates throughout the bulk
between hedgehog-anti-hedgehog pairs.Comment: 7 pages, 3 figure
Spectral Triples on Thermodynamic Formalism and Dixmier Trace Representations of Gibbs: theory and examples
In this paper we construct spectral triples on the symbolic space
when the alphabet is finite. We describe some new results for the associated
Dixmier trace representations for Gibbs probabilities (for potentials with less
regularity than H\"older) and for a certain class of functions. The Dixmier
trace representation can be expressed as the limit of a certain zeta function
obtained from high order iterations of the Ruelle operator. Among other things
we consider a class of examples where we can exhibit the explicit expression
for the zeta function. We are also able to apply our reasoning for some
parameters of the Dyson model (a potential on the symbolic space
) and for a certain class of observables. Nice results by
R. Sharp, M.~Kesseb\"ohmer and T.~Samuel for Dixmier trace representations of
Gibbs probabilities considered the case where the potential is of H\"older
class. We also analyze a particular case of a pathological continuous potential
where the Dixmier trace representation - via the associated zeta function - is
not true.Comment: the tile was modified and there are two more author
Solar activity during the Holocene: the Hallstatt cycle and its consequence for grand minima and maxim
Cosmogenic isotopes provide the only quantitative proxy for analyzing the
long-term solar variability over a centennial timescale. While essential
progress has been achieved in both measurements and modeling of the cosmogenic
proxy, uncertainties still remain in the determination of the geomagnetic
dipole moment evolution. Here we improve the reconstruction of solar activity
over the past nine millennia using a multi-proxy approach. We used records of
the 14C and 10Be cosmogenic isotopes, current numerical models of the isotope
production and transport in Earth's atmosphere, and available geomagnetic field
reconstructions, including a new reconstruction relying on an updated
archeo-/paleointensity database. The obtained series were analyzed using the
singular spectrum analysis (SSA) method to study the millennial-scale trends. A
new reconstruction of the geomagnetic dipole field moment, GMAG.9k, is built
for the last nine millennia. New reconstructions of solar activity covering the
last nine millennia, quantified in sunspot numbers, are presented and analyzed.
A conservative list of grand minima and maxima is provided. The primary
components of the reconstructed solar activity, as determined using the SSA
method, are different for the series based on 14C and 10Be. These primary
components can only be ascribed to long-term changes in the terrestrial system
and not to the Sun. They have been removed from the reconstructed series. In
contrast, the secondary SSA components of the reconstructed solar activity are
found to be dominated by a common ~2400-yr quasi-periodicity, the so-called
Hallstatt cycle, in both the 14C and 10Be based series. This Hallstatt cycle
thus appears to be related to solar activity. Finally, we show that the grand
minima and maxima occurred intermittently over the studied period, with
clustering near highs and lows of the Hallstatt cycle, respectively.Comment: In press in Astronomy & Astrophysics, doi:
10.1051/0004-6361/20152729
Vascular dysfunction and fibrosis in stroke-prone spontaneously hypertensive rats: the aldosterone-mineralocorticoid receptor-Nox1 Axis
Aims:
We questioned whether aldosterone and oxidative stress play a role in vascular damage in severe hypertension and investigated the role of Nox1 in this process.
Materials and methods:
We studied mesenteric arteries, aortas and vascular smooth muscle cells (VSMC) from WKY and SHRSP rats. Vascular effects of eplerenone or canrenoic acid (CA) (mineralocorticoid receptor (MR) blockers), ML171 (Nox1 inhibitor) and EHT1864 (Rac1/2 inhibitor) were assessed. Nox1-knockout mice were also studied. Vessels and VSMCs were probed for Noxs, reactive oxygen species (ROS) and pro-fibrotic/inflammatory signaling.
Key findings:
Blood pressure and plasma levels of aldosterone and galectin-3 were increased in SHRSP versus WKY. Acetylcholine-induced vasorelaxation was decreased (61% vs 115%) and phenylephrine-induced contraction increased in SHRSP versus WKY (Emax 132.8% vs 96.9%, p < 0.05). Eplerenone, ML171 and EHT1864 attenuated hypercontractility in SHRSP. Vascular expression of collagen, fibronectin, TGFβ, MCP-1, RANTES, MMP2, MMP9 and p66Shc was increased in SHRSP versus WKY. These changes were associated with increased ROS generation, 3-nitrotyrosine expression and Nox1 upregulation. Activation of vascular p66Shc and increased expression of Nox1 and collagen I were prevented by CA in SHRSP. Nox1 expression was increased in aldosterone-stimulated WKY VSMCs, an effect that was amplified in SHRSP VSMCs (5.2vs9.9 fold-increase). ML171 prevented aldosterone-induced VSMC Nox1-ROS production. Aldosterone increased vascular expression of fibronectin and PAI-1 in wild-type mice but not in Nox1-knockout mice.
Significance:
Our findings suggest that aldosterone, which is increased in SHRSP, induces vascular damage through MR-Nox1-p66Shc-mediated processes that modulate pro-fibrotic and pro-inflammatory signaling pathways
Market opportunities, customer desires and purchasing selectiveness modelling in multi-layered cellular automata: A study case on organizational survivability
The present work aims to contribute to a better understanding of the dynamics of organizational competition and survival in a supply chain network market context, while highlighting the potential of multi-layered cellular automata models as frameworks for accommodating increasing levels of complexity. More particularly, the implementation of inter-layer rules associated to k-bit words modelling of market opportunities, customer desires and purchasing selectiveness, and their impact on the dynamics of an evolutionary “ecology” of suppliers, competing organizations, and customers, following a complex adaptive systems approach is described and illustrated through a study case on organizational survivability. The implications of the study results—reflecting the interplay between market environment, competitors’ strategic choice, and corresponding ability to succeed, survive crises and proliferate—are then discussed and the main aims of the work ahead highlighted.info:eu-repo/semantics/acceptedVersio
An empirical analysis of the influence of macroeconomic determinants on World tourism demand
This paper considers three econometric models to determine the relationship between macroeconomic variables and tourism demand. Tourism demand is measured by the inbound visitor's population and also by on-the-ground expenditures. Macroeconomic determinants include the exchange rate, the relative domestic prices, and the World GDP per capita.
The database is an unbalanced panel of 218 countries over the period 1995-2012. There is evidence that an increase in the World's GDP per capita, a depreciation of the national currency, and a decline of relative domestic prices do help boosting the number of arrivals
and the correspondent expenditure level. The World's GDP per capita is more relevant when explaining arrivals, but relative prices become more important when we use expenditures as the proxy for tourism demand. In particular, we cannot reject the hypothesis of a relative prices unitary elasticity of expenditures. Additionally, we have also partitioned our data by
income level and by continent. Results are robust in the first partition, but less robust in the second, although the main conclusions still hold.info:eu-repo/semantics/acceptedVersio
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