431 research outputs found

    Le B. Raymond Lulle et Raymond Marti O. P.

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    Fact Sheet: Role of Occupational Therapy

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    https://nsuworks.nova.edu/hpd_ot_faculty_books/1011/thumbnail.jp

    A Personal Perspective on Daily Occupations to Counteract Cancer Related Fatigue: A Case Study

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    Background: This case study aimed to identify and describe meaningful physical occupations used by a cancer survivor to increase or maintain levels of participation during active chemotherapy and subsequent cancer related fatigue. Method: A case study approach was used to develop an in-depth description and analysis based on one participant’s experience with breast cancer and associated treatments. A semi-structured interview was conducted. The data were analyzed through description of the case, categories, and themes. It also included categorical aggregation in efforts to seek a collection of instances from the data to explore any issue-relevant meanings. Results: Following data analysis, one overarching theme, return to normalcy, was identified with three subthemes: (a) prioritization of meaningful activities, (b) modifications to activities or routines, (c) lack of referral for immediate needs. Conclusion: Personal knowledge of occupational therapy practice provided support for enhancing engagement in daily meaningful occupations. Lessons learned from this experience could be applied to clients experiencing cancer related side effects to improve engagement in daily occupations

    William Bill Longpre and Lena Marceau Longpre Interview, July 26, 1977

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    William Longpre discusses the history of the Ninemile Remount Depot, including the land the Depot was built on, the Depot itself, and people such as Locke M. (L. M.) Stewart, Ed MacKay, Evan W. “Major” Kelley, W. C. Evans, Hank Viche, Jesse “Jake” Williams, Hugh Redding, and Harold Dunn. He also describes his experiences with rodeos, bucking contests, and breaking mules.https://scholarworks.umt.edu/ninemileremountdepot/1011/thumbnail.jp

    Cucurbitacin E has neuroprotective properties and autophagic modulating activities on dopaminergic neurons

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    Natural molecules are under intensive study for their potential as preventive and/or adjuvant therapies for neurodegenerative disorders such as Parkinson’s disease (PD). We evaluated the neuroprotective potential of cucurbitacin E (CuE), a tetracyclic triterpenoid phytosterol extracted from the Ecballium elaterium (Cucurbitaceae), using a known cellular model of PD, NGF-differentiated PC12. In our postmitotic experimental paradigm, neuronal cells were treated with the parkinsonian toxin 1-methyl-4-phenylpyridinium (MPP+) to provoke significant cellular damage and apoptosis or with the potent N,N-diethyldithiocarbamate (DDC) to induce superoxide () production, and CuE was administered prior to and during the neurotoxic treatment. We measured cellular death and reactive oxygen species to evaluate the antioxidant and antiapoptotic properties of CuE. In addition, we analyzed cellular macroautophagy, a bulk degradation process involving the lysosomal pathway. CuE showed neuroprotective effects on MPP+-induced cell death. However, CuE failed to rescue neuronal cells from oxidative stress induced by MPP+ or DDC. Microscopy and western blot data show an intriguing involvement of CuE in maintaining lysosomal distribution and decreasing autophagy flux. Altogether, these data indicate that CuE decreases neuronal death and autophagic flux in a postmitotic cellular model of PD.peer-reviewe

    Sexual Harassment, Rape Myths and Paraphilias in the General Population: A Mediation Analysis Study

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    Purpose: Sexual harassment is a worldwide and prevalent problem that can have severe consequences. The #MeToo movement has highlighted that sexual harassment is not an isolated event and is linked to misogynistic cognitions and other forms of sexual violence. However, there is a lack of research regarding the relationship between sexual harassment and its nomological network, particularly in the general population.Design: The aim of the present study was to explore the relationship between perception of harassment and Rape Myths, with paraphilia (fantasy &amp; behaviour) as mediators. Additionally, the prevalence of paraphilia in the general population was explored and gender difference was analysed. Frequencies, Pearson's r correlations, independent sample t-tests and mediation analyses were conducted on a sample of N = 254 participants from the general population.Findings: Analyses revealed that half of the sample have engaged in at least one paraphilia behaviour. Furthermore, correlations between a more lenient perception of harassment, rape myth acceptance and paraphilia were found, as well as significant gender differences. Finally, mediation models revealed a strong relationship between rape myth acceptance and a more lenient perception of harassment, with paraphilia mediating this relationship.Originality: Current research is mostly conducted on male samples in these areas; thus, this study aimed to collect data from a diverse sample that may provide a better overview of sexual harassment, and its nomological network.Implications: This study has several implications, highlighting the role of misogynistic cognitions in predicting a lenient perception of sexual harassment, and thus, proposing a key focus for prevention and intervention models.<br/
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