Síndrome da tensão pré-menstrual observada em usuárias do ambulatório municipal de saúde da mulher

Many women suffer with Premenstrual Tension Syndrome (STPM) that has symptoms that precede menstruation, causing irritation, anxiety and low self esteem. The STPM affects women in the productive stage causing physical, psychological and social alterations.The aim of the research was to identify the users of an ambulatory health clinic of Tupanciretã, RS. This is a descriptive and exploratory study with qualitative-quantitative approaches. The results provided that women have STPM with different intensity, symptoms range from physical and mental and interfere with daily functioning of women.It was concluded that overall efforts, especially those from health professionals, and through practices which provide communication and health education for women affected by the STPM. In addition to the implementation of actions that provide changing habits, attitudes and behaviors that these women are looking for a better quality of life.Muchas mujeres sufren de Síndrome de Tensión Premenstrual (STPM), que presenta síntomas que anteceden a la menstruación, generando irritación, ansiedad y baja autoestima. El STPM afecta a mujeres en la etapa productiva provocando alteraciones físicas, psíquicas y sociales. El objetivo de la investigación fue identificar y caracterizar a las usuarias de un ambulatorio de salud del municipio de Tupanciretã-RS. Se trata de un estudio descriptivo y exploratorio con abordajes cuali-cuantitativos. Los resultados aportaron que las mujeres poseen STPM con diferente intensidad, los síntomas varían entre los físicos y psíquicos e interfieren en el desempeño cotidiano de las mujeres. Se concluye que es necesario el esfuerzo de los profesionales de salud, por medio de prácticas que proporcionen comunicación y educación en salud en las mujeres afectadas por el STPM. Aparte de la implementación de acciones que prevean cambios de hábitos, actitudes y comportamientos buscando que estas mujeres tengan una mejor calidad de vida. Muitas mulheres sofrem de Síndrome da Tensão Pré-Menstrual (STPM), síndrome que apresenta sintomas precedentes a menstruação, causando irritação, ansiedade e baixa autoestima. A STPM afeta as mulheres causando alterações física, psicológica e social. O objetivo da pesquisa foi identificar e caracterizar as usuárias de um ambulatório municipal de saúde no município de Tupanciretã - RS. Trata-se de um estudo descritivo e exploratório, com abordagem quali - quantitativa. Os resultados denotam que as mulheres têm STPM em diferente intensidade, os sintomas variam entre as mulheres, interferindo a ordem física e emocional. Conclui-se que se faz necessário o esforço dos profissionais de saúde, por meio de práticas que proporcionem comunicação e educação em saúde com as mulheres afetadas pela STPM. Além de ações que preveem mudanças de hábitos, atitudes e comportamentos a fim de que estas mulheres tenham uma melhor qualidade de vida

Cargo Transport by Cytoplasmic Dynein Can Center Embryonic Centrosomes

To complete meiosis II in animal cells, the male DNA material needs to meet the female DNA material contained in the female pronucleus at the egg center, but it is not known how the male pronucleus, deposited by the sperm at the periphery of the cell, finds the cell center in large eggs. Pronucleus centering is an active process that appears to involve microtubules and molecular motors. For small and medium-sized cells, the force required to move the centrosome can arise from either microtubule pushing on the cortex, or cortically-attached dynein pulling on microtubules. However, in large cells, such as the fertilized Xenopus laevis embryo, where microtubules are too long to support pushing forces or they do not reach all boundaries before centrosome centering begins, a different force generating mechanism must exist. Here, we present a centrosome positioning model in which the cytosolic drag experienced by cargoes hauled by cytoplasmic dynein on the sperm aster microtubules can move the centrosome towards the cell’s center. We find that small, fast cargoes (diameter ~100 nm, cargo velocity ~2 µm/s) are sufficient to move the centrosome in the geometry of the Xenopus laevis embryo within the experimentally observed length and time scales.This work was supported in part by the National Science Foundation grant PHY-0957811 to GTS. (www.nsf.gov) The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. No additional external funding was received for this study.PhysicsCellular and Molecular BiologyEmail: [email protected]

Centrosome dynamics as a function of vesicle velocity.

<p>(A) After an initial ramp up, the centrosome velocity keeps increasing at a much smaller rate. As the difference in number of vesicles moving along microtubules in the far and near cortical sides decreases, the centrosome slows down (arrows). Given that slower vesicles experience a smaller drag force, they lead to a slower centrosome. (B) The corresponding position of the centrosome shows that the small, fast-moving vesicles are sufficient to move the centrosome distances comparable to the motion of the centrosome in fertilized <i>Xenopus laevis</i> embryos. Experiments show that the centrosome moves at least 300 µm in 45 minutes; the dashed lines delineate that region. (calculation parameters: 100 microtubules; 100 nm diameter vesicles; viscosity ratio = 3; 2 vesicles/µm; 250 nm/s MT polymerization rate; vesicle velocity as indicated: 2 µm/s (green), 1 µm/s (red), 0.5 µm/s (black) in that order from top to bottom).</p

SÍNTESIS ENZIMÁTICA DE POLÍMEROS SEMICONDUCTORES UTILIZANDO LA CLOROPEROXIDASA DE CALDARIOMYCES FUMAGO

Uno de los descubrimientos más importantes del siglo pasado fue la capacidad de ciertos polímeros orgánicos para conducir electricidad. Entre los polímeros intrínsecamentente conductores más interesantes está la polianilina (PANI) cuya síntesis se hace química o electroquímicamente. Para que la PANI tenga mejores propiedades conductoras se requiere de un polímero lineal. La síntesis enzimática de polímeros se ha estudiado en los últimos años. En este trabajo se sintetizaron polímeros empleando la cloroperoxidasa de Caldariomyces fumago a partir de las anilinas sustituidas 2,6-dimetilanilina (DMA), 2,6-dicloroanilina (DCA) y 2,3,5,6- tetracloroanilina (TCA) con el fin de promover la polimerización lineal. Los polímeros fueron dopados con ácido (1S)-(+)-10-canforsulfónico (CSA), ácido dodecilbencensulfónico (DBSA) y ácido 2-acrilamido-2-metil-1- propanosulfónico (AMPSA) en relaciones molares 1:0.25 y 1:0.5. Los polímeros dopados muestran conductividades en la zona de semiconductores. El polímero de TCA dopado con AMPSA fue el que mostró los mayores valores de conductividad y al realizar un barrido a diferentes concentraciones de AMPSA se encontró que el complejo con una relación molar 1:0.5 tenía un valor de 1.6 x 10-2 S·m-1 que es similar a los valores obtenidos para otras anilinas sustituidas con grupos sulfónicos