Manifestation of Activity of Potentially Hazardous as regards Anthrax Areas across the Russian Federation under Current Conditions

Objective of the study is to investigate the activity of potentially hazardous as regards anthrax areas in the territory of the Russian Federation in 2001–2016. Materials and methods. The data was represented by the information contained in official reporting forms of the Department for Veterinary of the Ministry of Agriculture, statistical information from the Rospotrebnadzor and Rosselkhoznadzor on anthrax morbidity rates among animals and humans in our country, information on foci investigation and surveillance, cadastre of potentially hazardous as regards anthrax areas of the Russian Federation with amendments and additions included, as well as materials from publications and results of personal researches. Results and conclusions. The data on the contemporary manifestations of activity of 135 stationary potentially hazardous as regards anthrax areas of the Russian federation have been systematized and summarized; given has been the characteristics of old, relapsing, and new stationary hazardous as regards anthrax areas, registered in the Russian Federation since the beginning of the XXI century

Features of cellular structure of the induced sputum and profile of cytokines at sintropiya of bronchial asthma and obesity at young patients

Aim. To estimate changes of cellular structure of the induced sputum at young patients with bronchial asthma at interrelations with BMI and level of cytokines in blood plasma. Materials and methods. 164 patients with bronchial asthma were divided into 2 groups taking into BMI: the 1st group included patients with bronchial asthma and BMI from 18 to 25 kg/m2, patients with bronchial asthma and BMI from 30 to 40 kg/m2 entered into the 2nd group. The group of control was made by 40 almost healthy volunteers. Estimated existence of excess weight and defined obesity degree according to recommendations of World Health Organization. Studied the level of control of bronchial asthma, cellular structure of the induced sputum, the IL-2, IL-4, IL-6, IL-8, IL-10, IL-12, IL-15, IL-17, TNF-α, INF-γ levels in plasma of peripheral blood. Results. There are presented the results of the research of cellular profile of the induced sputum and profile of cytokines at patients with bronchial asthma depending on BMI and severity of the disease. The received results testify to prevalence of eosinophilic type of an inflammation in the group of patients with BMI less than 25 kg/m2 whereas at patients mainly paucigranulation inflammation decided on obesity. The highest content of the Il-17 was registered at patients with bronchial asthma and obesity as in comparison with indicators of patients with normal BMI, and with almost healthy that, perhaps, is the reason of low effect of steroid therapy at these patients. Conclusion. Endotype assessment before basic antiinflammatory therapy at patients with the first time diagnosed bronchial asthma, will be able to help with selection of the most optimum treatment to each specific patient

ANTHRAX IN THE TERRITORY OF YAMAL: ASSESSMENT OF EPIZOOTIOLOGICAL AND EPIDEMIOLOGICAL RISKS

Objective of the study was to analyze epizootiological and epidemiological risks contributing to the development of anthrax outbreak in the Yamal peninsular in July-August, 2016. Materials and methods. Risks were evaluated using complex approach allowing for determination of the impact of epidemiologically significant social, natural, and biological risks, based on literature sources, archival data, and statistical reports. Special focus was on the natural-climatic factors, providing for persistence of the agent in the environment, such as NDVI index, atmospheric temperature and humidity, as well as soil temperature and moisture at different depths, in accordance with satellite monitoring. Results and conclusions. Justified was the hypothesis on sustained adversity of soil foci in Yamal, remaining hazard of aggravation of epizootiological and epidemiological situation on anthrax against the background of changing environmental and social risk factors, as well as agent ability to survive in the soils within an indeterminate amount of time

Forward pi^0 Production and Associated Transverse Energy Flow in Deep-Inelastic Scattering at HERA

Deep-inelastic positron-proton interactions at low values of Bjorken-x down to x \approx 4.10^-5 which give rise to high transverse momentum pi^0 mesons are studied with the H1 experiment at HERA. The inclusive cross section for pi^0 mesons produced at small angles with respect to the proton remnant (the forward region) is presented as a function of the transverse momentum and energy of the pi^0 and of the four-momentum transfer Q^2 and Bjorken-x. Measurements are also presented of the transverse energy flow in events containing a forward pi^0 meson. Hadronic final state calculations based on QCD models implementing different parton evolution schemes are confronted with the data.Comment: 27 pages, 8 figures and 3 table

Search for Doubly-Charged Higgs Boson Production at HERA

A search for the single production of doubly-charged Higgs bosons H^{\pm \pm} in ep collisions is presented. The signal is searched for via the Higgs decays into a high mass pair of same charge leptons, one of them being an electron. The analysis uses up to 118 pb^{-1} of ep data collected by the H1 experiment at HERA. No evidence for doubly-charged Higgs production is observed and mass dependent upper limits are derived on the Yukawa couplings h_{el} of the Higgs boson to an electron-lepton pair. Assuming that the doubly-charged Higgs only decays into an electron and a muon via a coupling of electromagnetic strength h_{e \mu} = \sqrt{4 \pi \alpha_{em}} = 0.3, a lower limit of 141 GeV on the H^{\pm\pm} mass is obtained at the 95% confidence level. For a doubly-charged Higgs decaying only into an electron and a tau and a coupling h_{e\tau} = 0.3, masses below 112 GeV are ruled out.Comment: 15 pages, 3 figures, 1 tabl

Searches at HERA for Squarks in R-Parity Violating Supersymmetry

A search for squarks in R-parity violating supersymmetry is performed in e^+p collisions at HERA at a centre of mass energy of 300 GeV, using H1 data corresponding to an integrated luminosity of 37 pb^(-1). The direct production of single squarks of any generation in positron-quark fusion via a Yukawa coupling lambda' is considered, taking into account R-parity violating and conserving decays of the squarks. No significant deviation from the Standard Model expectation is found. The results are interpreted in terms of constraints within the Minimal Supersymmetric Standard Model (MSSM), the constrained MSSM and the minimal Supergravity model, and their sensitivity to the model parameters is studied in detail. For a Yukawa coupling of electromagnetic strength, squark masses below 260 GeV are excluded at 95% confidence level in a large part of the parameter space. For a 100 times smaller coupling strength masses up to 182 GeV are excluded.Comment: 32 pages, 14 figures, 3 table

Deep-Inelastic Inclusive ep Scattering at Low x and a Determination of alpha_s

A precise measurement of the inclusive deep-inelastic e^+p scattering cross section is reported in the kinematic range 1.5<= Q^2 <=150 GeV^2 and 3*10^(-5)<= x <=0.2. The data were recorded with the H1 detector at HERA in 1996 and 1997, and correspond to an integrated luminosity of 20 pb^(-1). The double differential cross section, from which the proton structure function F_2(x,Q^2) and the longitudinal structure function F_L(x,Q^2) are extracted, is measured with typically 1% statistical and 3% systematic uncertainties. The measured partial derivative (dF_2(x,Q^2)/dln Q^2)_x is observed to rise continuously towards small x for fixed Q^2. The cross section data are combined with published H1 measurements at high Q^2 for a next-to-leading order DGLAP QCD analysis.The H1 data determine the gluon momentum distribution in the range 3*10^(-4)<= x <=0.1 to within an experimental accuracy of about 3% for Q^2 =20 GeV^2. A fit of the H1 measurements and the mu p data of the BCDMS collaboration allows the strong coupling constant alpha_s and the gluon distribution to be simultaneously determined. A value of alpha _s(M_Z^2)=0.1150+-0.0017 (exp) +0.0009-0.0005 (model) is obtained in NLO, with an additional theoretical uncertainty of about +-0.005, mainly due to the uncertainty of the renormalisation scale.Comment: 68 pages, 24 figures and 18 table

Bound oxygen influence on the phase composition and electrical properties of semi-insulating silicon films

The purpose of this work is to establish of the bound oxygen effect on the phase composition of the Semi-Insulating Polycrystalline Oxygen-doped Silicon (SIPOS) films by means of three independent methods: X-ray diffraction (XRD), Ultrasoft X-ray Emission Spectroscopy (USXES) and Raman spectroscopy, also on their electrophysical properties, depending on the relative oxygen content in the gas mixture flow (γ=N2O/SiH4) of the plasma reactor during the chemical vapor deposition of submicron SIPOS layers on monocrystalline silicon wafers. The increase in the oxygen content in SIPOS layers from γ=0 to maximum at γ=0.15 leads to the reduction of Si nanocrystals size from ~75 nm to 2–5 nm, submerged in amorphous matrix. Oxygen is contained in the bound form of silicon-oxygen clusters SiOSi3 type in the amorphous silicon matrix without SiO2 formation. These nonlinear qualitative and quantitative changes in the atomic structure of the SIPOS layers under the influence of bound oxygen increase not only the resistivity of the films by two orders of magnitude but also the activation energy of conductivity in comparison with silicon at the temperatures above room temperature. © 2020 Elsevier LtdRussian Foundation for Basic Research, RFBR: 19-42-363013MD-42.2019.2Ministry of Science and Higher Education of the Russian FederationThe reported study was funded by RFBR and Government of Voronezh region according to the research project № 19-42-363013.The part of work was carried out with the support of the Ministry of Science and Higher Education of Russia Federation under the grand No. FZGU-2020-0036 .In part of diagnostics of the structures the work of P.V. Seredin was supported by the RF President's Grants Council (Grant MD-42.2019.2)