5,757 research outputs found
Assessment of synchrony in multiple neural spike trains using loglinear point process models
Neural spike trains, which are sequences of very brief jumps in voltage
across the cell membrane, were one of the motivating applications for the
development of point process methodology. Early work required the assumption of
stationarity, but contemporary experiments often use time-varying stimuli and
produce time-varying neural responses. More recently, many statistical methods
have been developed for nonstationary neural point process data. There has also
been much interest in identifying synchrony, meaning events across two or more
neurons that are nearly simultaneous at the time scale of the recordings. A
natural statistical approach is to discretize time, using short time bins, and
to introduce loglinear models for dependency among neurons, but previous use of
loglinear modeling technology has assumed stationarity. We introduce a succinct
yet powerful class of time-varying loglinear models by (a) allowing
individual-neuron effects (main effects) to involve time-varying intensities;
(b) also allowing the individual-neuron effects to involve autocovariation
effects (history effects) due to past spiking, (c) assuming excess synchrony
effects (interaction effects) do not depend on history, and (d) assuming all
effects vary smoothly across time.Comment: Published in at http://dx.doi.org/10.1214/10-AOAS429 the Annals of
Applied Statistics (http://www.imstat.org/aoas/) by the Institute of
Mathematical Statistics (http://www.imstat.org
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GENOME WIDE DNA METHYLATION PROFILING IS PREDICTIVE OF OUTCOME IN JUVENILE MYELOMONOCYTIC LEUKEMIA
The Nature of the H2-Emitting Gas in the Crab Nebula
Understanding how molecules and dust might have formed within a rapidly
expanding young supernova remnant is important because of the obvious
application to vigorous supernova activity at very high redshift. In previous
papers, we found that the H2 emission is often quite strong, correlates with
optical low-ionization emission lines, and has a surprisingly high excitation
temperature. Here we study Knot 51, a representative, bright example, for which
we have available long slit optical and NIR spectra covering emission lines
from ionized, neutral, and molecular gas, as well as HST visible and SOAR
Telescope NIR narrow-band images. We present a series of CLOUDY simulations to
probe the excitation mechanisms, formation processes and dust content in
environments that can produce the observed H2 emission. We do not try for an
exact match between model and observations given Knot 51's ambiguous geometry.
Rather, we aim to explain how the bright H2 emission lines can be formed from
within the volume of Knot 51 that also produces the observed optical emission
from ionized and neutral gas. Our models that are powered only by the Crab's
synchrotron radiation are ruled out because they cannot reproduce the strong,
thermal H2 emission. The simulations that come closest to fitting the
observations have the core of Knot 51 almost entirely atomic with the H2
emission coming from just a trace molecular component, and in which there is
extra heating. In this unusual environment, H2 forms primarily by associative
detachment rather than grain catalysis. In this picture, the 55 H2-emitting
cores that we have previously catalogued in the Crab have a total mass of about
0.1 M_sun, which is about 5% of the total mass of the system of filaments. We
also explore the effect of varying the dust abundance. We discuss possible
future observations that could further elucidate the nature of these H2 knots.Comment: 51 pages, 15 figures, accepted for publication in MNRAS, revised
Figure 12 results unchange
Vlasov Description Of Dense Quark Matter
We discuss properties of quark matter at finite baryon densities and zero
temperature in a Vlasov approach. We use a screened interquark Richardson's
potential consistent with the indications of Lattice QCD calculations.
We analyze the choices of the quark masses and the parameters entering the
potential which reproduce the binding energy (B.E.) of infinite nuclear matter.
There is a transition from nuclear to quark matter at densities 5 times above
normal nuclear matter density. The transition could be revealed from the
determination of the position of the shifted meson masses in dense baryonic
matter. A scaling form of the meson masses in dense matter is given.Comment: 15 pages 4 figure
A Time-Accurate Upwind Unstructured Finite Volume Method for Compressible Flow with Cure of Pathological Behaviors
A time-accurate, upwind, finite volume method for computing compressible flows on unstructured grids is presented. The method is second order accurate in space and time and yields high resolution in the presence of discontinuities. For efficiency, the Roe approximate Riemann solver with an entropy correction is employed. In the basic Euler/Navier-Stokes scheme, many concepts of high order upwind schemes are adopted: the surface flux integrals are carefully treated, a Cauchy-Kowalewski time-stepping scheme is used in the time-marching stage, and a multidimensional limiter is applied in the reconstruction stage. However even with these up-to-date improvements, the basic upwind scheme is still plagued by the so-called "pathological behaviors," e.g., the carbuncle phenomenon, the expansion shock, etc. A solution to these limitations is presented which uses a very simple dissipation model while still preserving second order accuracy. This scheme is referred to as the enhanced time-accurate upwind (ETAU) scheme in this paper. The unstructured grid capability renders flexibility for use in complex geometry; and the present ETAU Euler/Navier-Stokes scheme is capable of handling a broad spectrum of flow regimes from high supersonic to subsonic at very low Mach number, appropriate for both CFD (computational fluid dynamics) and CAA (computational aeroacoustics). Numerous examples are included to demonstrate the robustness of the methods
CONGENITAL ATLANTO-AXIAL DISLOCATION
Atlanto-axial dislocation IS an uncommon condition. It is usually secondary to trauma, infection (tuberculous and non-tuberculous atlas and axis) and rheumatoid arthritis. Othe
A Survey of Molecular Hydrogen in the Crab Nebula
We have carried out a near-infrared, narrow-band imaging survey of the Crab
Nebula, in the H2 2.12 micron and Br-gamma 2.17 micron lines, using the Spartan
Infrared camera on the SOAR Telescope. Over a 2.8' x 5.1' area that encompasses
about 2/3 of the full visible extent of the Crab, we detect 55 knots that emit
strongly in the H2 line. We catalog the observed properties of these knots. We
show that they are in or next to the filaments that are seen in
optical-passband emission lines. Comparison to HST [S II] and [O III] images
shows that the H2 knots are strongly associated with compact regions of
low-ionization gas. We also find evidence of many additional, fainter H2
features, both discrete knots and long streamers following gas that emits
strongly in [S II]. A pixel-by-pixel analysis shows that about 6 percent of the
Crab's projected surface area has significant H2 emission that correlates with
[S II] emission. We measured radial velocities of the [S II] lambda6716
emission lines from 47 of the cataloged knots and find that most are on the far
(receding) side of the nebula. We also detect Br-gamma emission. It is right at
the limit of our survey, and our Br-gamma filter cuts off part of the expected
velocity range. But clearly the Br-gamma emission has a quite different
morphology than the H2 knots, following the long linear filaments that are seen
in H-alpha and in [O III] optical emission lines.Comment: Accepted for publication in the ApJ
Near-Field Noise Computation for a Subsonic Coannular Jet
A high-Reynolds-number, subsonic coannular jet is simulated, using a three-dimensional finite-volume LES method, with emphasis on the near field noise. The nozzle geometry used is the NASA Glenn 3BB baseline model. The numerical results are generally in good agreement with existing experimental findings
Zone Determinant Expansions for Nuclear Lattice Simulations
We introduce a new approximation to nucleon matrix determinants that is
physically motivated by chiral effective theory. The method involves breaking
the lattice into spatial zones and expanding the determinant in powers of the
boundary hopping parameter.Comment: 20 pages, 6 figures, revtex4 (version to appear in PRC
Finite-Temperature Monte Carlo Calculations For Systems With Fermions
We present a quantum Monte Carlo method which allows calculations on
many-fermion systems at finite temperatures without any sign decay. This
enables simulations of the grand-canonical ensemble at large system sizes and
low temperatures. Both diagonal and off-diagonal expectations can be computed
straightforwardly. The sign decay is eliminated by a constraint on the fermion
determinant. The algorithm is approximate. Tests on the Hubbard model show that
accurate results on the energy and correlation functions can be obtained.Comment: 5 pages, RevTex; to appear in Phys. Rev. Let
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