607 research outputs found
Antiproton annihilation on light nuclei at very low energies
The recent experimental data obtained by the OBELIX group on D and
He total annihilation cross sections are analyzed. The combined
analysis of these data with existing antiprotonic atom data allows, for the
first time, the imaginary parts of the S-wave scattering lengths for the two
nuclei to be extracted. The obtained values are: for D and for He. This
analysis indicates an unexpected behaviour of the imaginary part of the
-nucleus S-wave scattering length as a function of the atomic weight
A: (p) > (D) > (He).Comment: 13 pages, 5 figure
Experimental evidence of antiproton reflection by a solid surface
We report here experimental evidence of the reflection of a large fraction of
a beam of low energy antiprotons by an aluminum wall. This derives from the
analysis of a set of annihilations of antiprotons that come to rest in rarefied
helium gas after hitting the end wall of the apparatus. A Monte Carlo
simulation of the antiproton path in aluminum indicates that the observed
reflection occurs primarily via a multiple Rutherford-style scattering on Al
nuclei, at least in the energy range 1-10 keV where the phenomenon is most
visible in the analyzed data. These results contradict the common belief
according to which the interactions between matter and antimatter are dominated
by the reciprocally destructive phenomenon of annihilation.Comment: 5 pages with 5 figure
Limits on the low energy antinucleon-nucleus annihilations from the Heisenberg principle
We show that the quantum uncertainty principle puts some limits on the
effectiveness of the antinucleon-nucleus annihilation at very low energies.
This is caused by the fact that the realization a very effective short-distance
reaction process implies information on the relative distance of the reacting
particles. Some quantitative predictions are possible on this ground, including
the approximate A-independence of antinucleon-nucleus annihilation rates.Comment: 10 pages, no figure
Antiparticle cloud temperatures for antihydrogen experiments
An analysis of positron and antiproton cloud temperatures under condition similar to those found in antihydrogen experiments.Some simple general trends are brought out in the analysis, which includes the effects of cloud expansion for the first time
Impact of 18F-FDG PET/CT on Clinical Management of Suspected Radio-Iodine Refractory Differentiated Thyroid Cancer (RAI-R-DTC).
Background: As reported in the literature, [18F]-fluorodeoxyglucose positron emission tomography/computed tomography ([18F]-FDG PET/CT) provides useful qualitative and semi-quantitative data for the prognosis of advanced differentiated thyroid cancer. Instead, there is a lack of data about the real clinical impact of 18F-FDG PET/CT on the choice of the more effective therapeutic approach for advanced differentiated thyroid cancer (DTC) that starts to lose iodine avidity. The primary aim of this retrospective study was to assess how 18F-FDG PET/CT can guide the choice of the best therapeutic approach to RAI-refractory DTC (RAI-R-DTC) in patients with a doubtful iodine uptake/negative 18F-FDG PET/CT I whole-body scan after several radioactive iodine therapies (RAIT). The secondary aim was to assess the prognostic role of clinical and semi-quantitative metabolic 18F-FDG PET/CT parameters in comparison to published data.
Materials and methods: A monocentric retrospective observational study was performed, reviewing the medical records of 53 patients recruited from a database of 208 patients treated at our Institution between 2011 and 2019, with advanced DTC that underwent FDG PET/CT scan for a suspected RAI-R-DTC. Selected patients had to perform a 18F-FDG PET/CT scan after the second RAIT based on a doubtful iodine uptake/negative 131 I whole-body scan and/or persistent elevated thyroglobulin levels. Metabolic response was defined according to positron emission tomography response criteria in solid tumors (PERCIST) guidelines. Standardized uptake value (SUV)max, SUVmean, metabolic tumor volume (MTV), and total lesion glycolysis (TLG) were calculated. The association between metabolic features, clinical parameters and progression free survival (PFS) was assessed applying Kruskal-Wallis, chi-square-Pearson correlation tests, and Cox regression analyses when appropriate.
Results: Among our sample of 53 patients (mean age 52.0 ± 19.9 years; 31 women and 22 men), 27 (51.0%) presented a positive 18F-FDG PET/CT scan: 16 (59.0%) underwent watchful waiting, 4 (15.0%) received external-beam radiation therapy (EBRT), 4 (15.0%) underwent surgery, 2 (7.4%) received another course of RAI therapy, and 1 underwent surgery + EBRT. PERCIST response was evaluated in 14/27 patients. Median follow-up was 5.8 ± 3.9 years and median PFS was 38.0 ± 21.8 months. At the last follow-up assessment, 14/53 (26.4%) demonstrated disease progression, 13/53 (24.5) persistence of structural disease, 25/53 (47%) persistence of biochemical disease, and 15/53 (28%) had an excellent response. A significant association was found between therapeutic approach, metabolic response, and final disease response evaluation, as well as a linear correlation between MTV and TLG with thyroglobulin level.
Conclusions: Our Institutional experience confirmed the role of 18F-FDG PET/CT as a useful guide in the clinical management of RAI-R-DTC and obviated further unnecessary RAIT
A phenomenological analysis of antiproton interactions at low energies
We present an optical potential analysis of the antiproton-proton
interactions at low energies. Our optical potential is purely phenomenological,
and has been parametrized on data recently obtained by the Obelix Collaboration
at momenta below 180 MeV/c. It reasonably fits annihilation and elastic data
below 600 MeV/c, and allows us for an evaluation of the elastic cross section
and rho-parameter down to zero kinetic energy. Moreover we show that the
mechanism that depresses antiproton-nucleus annihilation cross sections at low
energies is present in antiproton-proton interactions too.Comment: 10 pages, 4 figure
Coulomb corrections to low energy antiproton annihilation cross sections on protons and nuclei
We calculate, in a systematic way, the enhancement effect on
antiproton-proton and antiproton-nucleus annihilation cross sections at low
energy due to the initial state electrostatic interaction between the
projectile and the target nucleus. This calculation is aimed at future
comparisons between antineutron and antiproton annihilation rates on different
targets, for the extraction of pure isospin channels.Comment: 18 pages, 4 figures (latex format
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