6,686 research outputs found

    Surviving the rollercoaster: The professional identity development of Latinx doctoral students in counseling

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    This qualitative study applies Latino Critical Race theory to understand the professional identity development of eight Latinx doctoral students in counseling. The three themes: being one of the few, navigating professional identity, and becoming a counselor educator, depict how they persisted despite racialized experiences. The metaphor of a rollercoaster captures their experience of resistance and disruption to the norm. Implications for counselor educators and counseling programs are provided. These are aimed at creating an anti-racist profession that is inclusive of all students. Keywords: professional identity, Latinx doctoral students, counselor education, racism, Latino Critical Race Theor

    Alien Registration- Locke, Charles F. (Brunswick, Cumberland County)

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    https://digitalmaine.com/alien_docs/31537/thumbnail.jp

    Silver Spray

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    https://digitalcommons.library.umaine.edu/mmb-ps/1656/thumbnail.jp

    Safe from Sex Offenders? Legislating Internet Publication of Sex Offender Registries

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    In July 2005, the U.S. Department of Justice implemented the National Sex Offender Public Registry, which links the registries of individual states. A year later, the Adam Walsh Bill created the Dru Sjodin National Sex Offender Public Website, which required the Department of Justice to maintain a comprehensive national sex offender registry. The purpose of this article is to examine the statutory provisions of every state and the District of Columbia regarding the use of the Internet as a tool in administering Megan\u27s Law. The analysis begins by examining sex offender registration and notification laws at the federal level and discussing major federal legislation and United States Supreme Court cases that impact how states draft their Megan\u27s Laws. Next, the portions of each state\u27s Megan\u27s Law that mentions the Internet as a notification tool, if any, are categorized. This article concludes that though state legislatures have embraced the Internet as a notification model, the model itself will not be effective unless the registry information disseminated is accurate and up-to-date. States can help ensure the effectiveness of online registries by including provisions in their statutes for the accuracy, timeliness, and publicity of the sites

    Role of microRNAs in the age-associated decline of pancreatic beta cell function in rat islets

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    This is a freely-available open access publication. Please cite the published version which is available via the DOI link in this record.AIMS/HYPOTHESIS: Ageing can lead to reduced insulin sensitivity and loss of pancreatic beta cell function, predisposing individuals to the development of diabetes. The aim of this study was to assess the contribution of microRNAs (miRNAs) to age-associated beta cell dysfunction. METHODS: The global mRNA and miRNA profiles of 3- and 12-month-old rat islets were collected by microarray. The functional impact of age-associated differences in miRNA expression was investigated by mimicking the observed changes in primary beta cells from young animals. RESULTS: Beta cells from 12-month-old rats retained normal insulin content and secretion, but failed to proliferate in response to mitotic stimuli. The islets of these animals displayed modifications at the level of several miRNAs, including upregulation of miR-34a, miR-124a and miR-383, and downregulation of miR-130b and miR-181a. Computational analysis of the transcriptomic modifications observed in the islets of 12-month-old rats revealed that the differentially expressed genes were enriched for miR-34a and miR-181a targets. Indeed, the induction of miR-34a and reduction of miR-181a in the islets of young animals mimicked the impaired beta cell proliferation observed in old animals. mRNA coding for alpha-type platelet-derived growth factor receptor, which is critical for compensatory beta cell mass expansion, is directly inhibited by miR34a and is likely to be at least partly responsible for the effects of this miRNA. CONCLUSIONS/INTERPRETATION: Changes in the level of specific miRNAs that occur during ageing affect the proliferative capacity of beta cells. This might reduce their ability to expand under conditions of increased insulin demand, favouring the development of type 2 diabetes.Swiss National Science FoundationFondation Francophone pour la Recherche sur le DiabèteWellcome Trust Senior Investigator AwardMRC Programme GrantRoyal Society Wolfson Research Merit AwardWellcome Trust project gran
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