951 research outputs found
A Novel 2D Folding Technique for Enhancing Fermi Surface Signatures in the Momentum Density: Application to Compton Scattering Data from an Al-3at%Li Disordered Alloy
We present a novel technique for enhancing Fermi surface (FS) signatures in
the 2D distribution obtained after the 3D momentum density in a crystal is
projected along a specific direction in momentum space. These results are
useful for investigating fermiology via high resolution Compton scattering and
positron annihilation spectroscopies. We focus on the particular case of the
(110) projection in an fcc crystal where the standard approach based on the use
of the Lock-Crisp-West (LCW) folding theorem fails to give a clear FS image due
to the strong overlap with FS images obtained through projection from higher
Brillouin zones. We show how these superposed FS images can be disentangled by
using a selected set of reciprocal lattice vectors in the folding process. The
applicability of our partial folding scheme is illustrated by considering
Compton spectra from an Al-3at%Li disordered alloy single crystal. For this
purpose, high resolution Compton profiles along nine directions in the (110)
plane were measured. Corresponding highly accurate theoretical profiles in
Al-3at%Li were computed within the local density approximation (LDA)-based
Korringa-Kohn-Rostoker coherent potential approximation (KKR-CPA)
first-principles framework. A good level of overall accord between theory and
experiment is obtained, some expected discrepancies reflecting electron
correlation effects notwithstanding, and the partial folding scheme is shown to
yield a clear FS image in the (110) plane in Al-3%Li.Comment: 24 pages, 8 figures, to appear in Phys. Rev.
What explains the well-being benefits of physical activity? A mixed-methods analysis of the roles of participation frequency and social identification
Objective
Physical activity in a social setting is said to be associated with well-being because it provides opportunities for participants to form social relationships. However, there are inconsistent findings regarding the well-being benefits of participating in physical activity with others. To address this inconclusive evidence, we draw on the social identity approach to health and well-being to examine whether (a) the frequency of physical activity participation in a social setting and (b) the degree of social identification associated with it, have different relationships with participants’ well-being.
Methods
We implemented a two-phase, mixed-methods design with members of women's only fitness clubs in Japan. In Study 1, we collected survey responses about social identification, life satisfaction, and eudaimonic well-being from 1118 members. The survey data were combined with respondents' objective participation data from a membership database. In Study 2, we interviewed a sample of club members to understand how the nature of social relationships differed depending on the degree of their social identification.
Results
Study 1 found that social identification with a fitness club, but not the frequency of attending the club for physical activity, was positively associated with members’ well-being. Study 2 revealed that members with high social identification experienced more affective relationships with other members than those with medium or low identification.
Conclusions
Our research provides quantitative and qualitative evidence supporting the association between social identification and the well-being benefits of physical activity in a social setting. It confirms the predictions of the social identity approach to health and well-being, demonstrating that people enjoy well-being benefits from physical activity participation when it is internalized as a meaningful definition of self
Elucidation on the Effect of Operating Temperature to the Transport Properties of Polymeric Membrane Using Molecular Simulation Tool
Existing reports of gas transport properties within polymeric membrane as a direct consequence of operating temperature are in a small number and have arrived in diverging conclusion. The scarcity has been associated to challenges in fabricating defect free membranes and empirical investigations of gas permeation performance at the laboratory scale that are often time consuming and costly. Molecular simulation has been proposed as a feasible alternative of experimentally studied materials to provide insights into gas transport characteristic. Hence, a sequence of molecular modelling procedures has been proposed to simulate polymeric membranes at varying operating temperatures in order to elucidate its effect to gas transport behaviour. The simulation model has been validated with experimental data through satisfactory agreement. Solubility has shown a decrement in value when increased in temperature (an average factor of 1.78), while the opposite has been observed for gas diffusivity (an average factor of 1.32) when the temperature is increased from 298.15Â K to 323.15Â K. In addition, it is found that permeability decreases by 1.36 times as the temperature is increased
Effectiveness of interventions to promote healthy diet in primary care: systematic review and meta-analysis of randomised controlled trials
Background
A diet rich in fruit, vegetables and dietary fibre and low in fat is associated with reduced risk of chronic disease. This review aimed to estimate the effectiveness of interventions to promote healthy diet for primary prevention among participants attending primary care.<p></p>
Methods
A systematic review of trials using individual or cluster randomisation of interventions delivered in primary care to promote dietary change over 12 months in healthy participants free from chronic disease or defined high risk states. Outcomes were change in fruit and vegetable intake, consumption of total fat and fibre and changes in serum cholesterol concentration.<p></p>
Results
Ten studies were included with 12,414 participants. The design and delivery of interventions were diverse with respect to grounding in behavioural theory and intervention intensity. A meta-analysis of three studies showed an increase in fruit consumption of 0.25 (0.01 to 0.49) servings per day, with an increase in vegetable consumption of 0.25 (0.06 to 0.44) serving per day. A further three studies that reported on fruit and vegetable consumption together showed a pooled increment of 0.50 (0.13 to 0.87) servings per day. The pooled effect on consumption of dietary fibre, from four studies, was estimated to be 1.97 (0.43 to 3.52) gm fibre per day. Data from five studies showed a mean decrease in total fat intake of 5.2% of total energy (1.5 to 8.8%). Data from three studies showed a mean decrease in serum cholesterol of 0.10 (-0.19 to 0.00) mmol/L.<p></p>
Conclusion
Presently-reported interventions to promote healthy diet for primary prevention in primary care, which illustrate a diverse range of intervention methods, may yield small beneficial changes in consumption of fruit, vegetables, fibre and fat over 12 months. The present results do not exclude the possibility that more effective intervention strategies might be developed.<p></p>
The Cerenkov effect revisited: from swimming ducks to zero modes in gravitational analogs
We present an interdisciplinary review of the generalized Cerenkov emission
of radiation from uniformly moving sources in the different contexts of
classical electromagnetism, superfluid hydrodynamics, and classical
hydrodynamics. The details of each specific physical systems enter our theory
via the dispersion law of the excitations. A geometrical recipe to obtain the
emission patterns in both real and wavevector space from the geometrical shape
of the dispersion law is discussed and applied to a number of cases of current
experimental interest. Some consequences of these emission processes onto the
stability of condensed-matter analogs of gravitational systems are finally
illustrated.Comment: Lecture Notes at the IX SIGRAV School on "Analogue Gravity" in Como,
Italy from May 16th-21th, 201
Nesting properties and anisotropy of the Fermi surface of LuNiBC
The rare earth nickel borocarbides, with the generic formula
NiBC, have recently been shown to display a rich variety of
phenomena. Most striking has been the competition between, and even coexistence
of, antiferromagnetism and superconductivity. We have measured the Fermi
surface (FS) of LuNiBC, and shown that it possesses nesting
features capable of explaining some of the phenomena experimentally observed.
In particular, it had previously been conjectured that a particular sheet of FS
is responsible for the modulated magnetic structures manifest in some of the
series. We report the first direct experimental observation of this sheet.Comment: 4 pages, 4 PS figure
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The use of phylogeny to interpret cross-cultural patterns in plant use and guide medicinal plant discovery: an example from Pterocarpus (Leguminosae)
The study of traditional knowledge of medicinal plants has led to discoveries that have helped combat diseases and improve healthcare. However, the development of quantitative measures that can assist our quest for new medicinal plants has not greatly advanced in recent years. Phylogenetic tools have entered many scientific fields in the last two decades to provide explanatory power, but have been overlooked in ethnomedicinal studies. Several studies show that medicinal properties are not randomly distributed in plant phylogenies, suggesting that phylogeny shapes ethnobotanical use. Nevertheless, empirical studies that explicitly combine ethnobotanical and phylogenetic information are scarce.In this study, we borrowed tools from community ecology phylogenetics to quantify significance of phylogenetic signal in medicinal properties in plants and identify nodes on phylogenies with high bioscreening potential. To do this, we produced an ethnomedicinal review from extensive literature research and a multi-locus phylogenetic hypothesis for the pantropical genus Pterocarpus (Leguminosae: Papilionoideae). We demonstrate that species used to treat a certain conditions, such as malaria, are significantly phylogenetically clumped and we highlight nodes in the phylogeny that are significantly overabundant in species used to treat certain conditions. These cross-cultural patterns in ethnomedicinal usage in Pterocarpus are interpreted in the light of phylogenetic relationships.This study provides techniques that enable the application of phylogenies in bioscreening, but also sheds light on the processes that shape cross-cultural ethnomedicinal patterns. This community phylogenetic approach demonstrates that similar ethnobotanical uses can arise in parallel in different areas where related plants are available. With a vast amount of ethnomedicinal and phylogenetic information available, we predict that this field, after further refinement of the techniques, will expand into similar research areas, such as pest management or the search for bioactive plant-based compounds
Disparate In Vivo Efficacy of FTY720 in Xenograft Models of Philadelphia Positive and Negative B-lineage Acute Lymphoblastic Leukemia
Most patients with acute lymphoblastic leukemia (ALL) respond well to standard chemotherapy-based treatments. However a significant proportion of patients, particularly adult patients, relapse with the majority dying of leukemia. FTY720 is an immunosuppressive drug that was recently approved for the treatment of multiple sclerosis and is currently under pre-clinical investigation as a therapy for a number of hematological malignancies. Using human ALL xenografts in NOD/SCIDγc−/− mice, we show for the first time that three Ph+ human ALL xenografts responded to FTY720 with an 80±12% (p = 0.048) reduction in overall disease when treatment was commenced early. In contrast, treatment of mice with FTY720 did not result in reduced leukemia compared to controls using four separate human Ph− ALL xenografts. Although FTY720 reactivated PP2A in vitro, this reactivation was not required for death of Ph− ALL cells. The plasma levels of FTY720 achieved in the mice were in the high nanomolar range. However, the response seen in the Ph+ ALL xenografts when treatment was initiated early implies that in vivo efficacy may be obtained with substantially lower drug concentrations than those required in vitro. Our data suggest that while FTY720 may have potential as a treatment for Ph+ ALL it will not be a useful agent for the treatment of Ph− B-ALL
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