The Development of the Use of Expert Testimony

The steadily increasing performance of modern computer systems is having a large influence on simulation technologies. It enables increasingly detailed simulations of larger and more comprehensive simulation models. Increasingly large amounts of numerical data are produced by these simulations. This thesis presents several contributions in the field of mechanical system simulation and visualisation. The work described in the thesis is of practical relevance and results have been tested and implemented in tools that are used daily in the industry i.e., the BEAST (BEAring Simulation Tool) tool box. BEAST is a multibody system (MBS) simulation software with special focus on detailed contact calculations. Our work is primarily focusing on these types of systems. focusing on these types of systems. Research in the field of simulation modelling typically focuses on one or several specific topics around the modelling and simulation work process. The work presented here is novel in the sense that it provides a complete analysis and tool chain for the whole work process for simulation modelling and analysis of multibody systems with detailed contact models. The focus is on detecting and dealing with possible problems and bottlenecks in the work process, with respect to multibody systems with detailed contact models. The following primary research questions have been formulated: How to utilise object-oriented techniques for modelling of multibody systems with special reference tocontact modelling? How to integrate visualisation with the modelling and simulation process of multibody systems withdetailed contacts. How to reuse and combine existing simulation models to simulate large mechanical systems consistingof several sub-systems by means of co-simulation modelling? Unique in this work is the focus on detailed contact models. Most modelling approaches for multibody systems focus on modelling of bodies and boundary conditions of such bodies, e.g., springs, dampers, and possibly simple contacts. Here an object oriented modelling approach for multibody simulation and modelling is presented that, in comparison to common approaches, puts emphasis on integrated contact modelling and visualisation. The visualisation techniques are commonly used to verify the system model visually and to analyse simulation results. Data visualisation covers a broad spectrum within research and development. The focus is often on detailed solutions covering a fraction of the whole visualisation process. The novel visualisation aspect of the work presented here is that it presents techniques covering the entire visualisation process integrated with modeling and simulation. This includes a novel data structure for efficient storage and visualisation of multidimensional transient surface related data from detailed contact calculations. Different mechanical system simulation models typically focus on different parts (sub-systems) of a system. To fully understand a complete mechanical system it is often necessary to investigate several or all parts simultaneously. One solution for a more complete system analysis is to couple different simulation models into one coherent simulation. Part of this work is concerned with such co-simulation modelling. Co-simulation modelling typically focuses on data handling, connection modelling, and numerical stability. This work puts all emphasis on ease of use, i.e., making mechanical system co-simulation modelling applicable for a larger group of people. A novel meta-model based approach for mechanical system co-simulation modelling is presented. The meta-modelling process has been defined and tools and techniques been created to fully support the complete process. A component integrator and modelling environment are presented that support automated interface detection, interface alignment with automated three-dimensional coordinate translations, and three dimensional visual co-simulation modelling. The integrated simulator is based on a general framework for mechanical system co-simulations that guarantees numerical stability

Imaging for endoscopic sinus surgery in adults

Computerized tomography (CT) offers the gold standard in terms of imaging the extent of disease and the fine detailed anatomy, both pre-requisites to the safe practice of endoscopic sinus surgery. Neither plain X-rays nor magnetic resonance imaging (MRI) offer optimal information in this respect. A variety of protocols minimizing radiation dose to the lens whilst providing high quality images are presented together with a menu of anatomical features that require careful evaluation pre-operatively

Optimum imaging for inverted papilloma

Inverted papilloma is the most common benign tumour of the nose and paranasal sinuses, and usually arises in the lateral wall of the nasal cavity and the middle meatus. The diagnosis is suggested on computed tomography (CT) when there is a mass continuous from the middle meatus into the adjacent maxillary antrum, through an expanded maxillary ostium. The mass may contain areas of high density or calcification, and there may be sclerosis of the wall of the affected sinus. The main advantage of magnetic resonance imaging (MRI) is in defining the extent of the tumour, and in differentiating it from adjacent inflammatory tissue, but there are no certain signal intensity or enhancement characteristics to help differentiate inverted papilloma from sinus malignancy. In the differential diagnosis, antro-choanal polyp, malignant sinus tumours and chronic rhinosinusitis and fungal disease need to be excluded. The combination of bone deformity and sclerosis with the typical antro-meatal mass suggests a slow-growing tumour such as inverted papilloma

Fungal rhinosinusitis

Fungal infections in both their invasive and non-invasive forms can prove difficult to diagnose. The often characteristic appearances on imaging are of great assistance. CT is the primary imaging modality and is probably more accurate than MRI in diagnostic specificity and determining the extent of bone erosion. However this may require a modified scanning technique to adequately demonstrate the typical soft tissue density variations of fungi. MRI should be used to supplement CT when intra-cranial or intra-orbital extension is suspected

Optimum imaging and diagnosis of cerebrospinal fluid rhinorrhoea

Imaging is an important component in the investigation of unilateral watery rhinorrhoea suspicious of cerebrospinal fluid (CSF). Whilst the demonstration of the presence of beta 2 transferrin confirms that CSF is present it may prove difficult to demonstrate the exact site of origin. Fine detail coronal computed tomography (CT) with sections of 1-2 mm thickness through the anterior skull base may show small dehiscences and fractures. The commonest site for congenital dehiscences is the cribriform niche adjacent to the vertical attachment of the middle turbinate anteriorly and the superior and lateral walls of the sphenoid posteriorly. In the presence of frequent or constant CSF rhinorrhoea a CT cisternogram can be helpful in defining the exact site of the leak. Magnetic resonance imaging (MRI) is reserved for defining the nature of soft tissue Le. inflammatory tissue, meningoencephalocele or tumour. Finally, per-operative intrathecal fluorescein is helpful when imaging does not prove positive. A management algorithm for CSF rhinorrhoea is presented