387 research outputs found

    Cycle-magic graphs

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    AbstractA simple graph G=(V,E) admits a cycle-covering if every edge in E belongs at least to one subgraph of G isomorphic to a given cycle C. Then the graph G is C-magic if there exists a total labelling f:V∪E→{1,2,…,|V|+|E|} such that, for every subgraph H′=(V′,E′) of G isomorphic to C, ∑v∈V′f(v)+∑e∈E′f(e) is constant. When f(V)={1,…,|V|}, then G is said to be C-supermagic.We study the cyclic-magic and cyclic-supermagic behavior of several classes of connected graphs. We give several families of Cr-magic graphs for each r⩾3. The results rely on a technique of partitioning sets of integers with special properties

    Comportamiento biológico intraarticular de distintos aloinjertos tendinosos: estudio experimental

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    Se ha efectuado un estudio experimental comparativo, con valoración macro y microscópica, de la supervivencia, dentro de la articulación de la rodilla del conejo, de tendones flexores sobre extensores y dentro de estos, entre tendones conservados en fresco, congelados, liofilizados y fijados en solución de glutaraldehido al 0,2%. Los tendones se mantuvieron libres en la articulación receptora durante periodos distintos de tiempo. Entre los resultados destaca la pérdida de volumen, en el tiempo, de la masa tendinosa (18% de despariciones totales, con un 28% de pérdida final global). Los tendones fijados en glutaraldehido fueron los que presentaron menor pérdida de volumen. Los tendones implantados en fresco y los congelados presentaron una mayor tasa de infección. La mejor respuesta de supervivencia se detectó en los tendones conservados en glutaraldehido y los congelados. Así mismo, tenían más posibilidades de sobrevivir los flexores que los extensores. Desde el punto de vista histológico, los tendones conservados en fresco desencadenaron una mayor respuesta inflamatoria, con gran alteración estructural. Desde el punto de vista microscópico no se han hallado diferencias significativas entre flexores y extensores.Different groups of flexor and extensor tendons have been compared in their abitihty survive within the rabbit knee joint. Tendons were grouped and compared according four different storage procedures like freezing, lyophylization and fixation in 0,2% glutaraldehid. Some of them were used in fresh. All tendons have been kept inside the joint as free graft. All specimens lost weight along the study (18% of total loosing of specimen, and 28% of global loosing). Tendons fixed in disclosed less loosing of volume. Allograft infection was related to the method o glutaraildehid of storage, relationship being statistically significant (fresh tendons and frozen tendons were infected more easily). The best survival was found in both frozen and glutaraldehid fixed tendons. Flexor tendons show more chances of survival than extensors tendons. Histologically, fresh tendons disclosed the greatest inflammatory reaction. Opposite to the macroscopic findings, there were no significant differences between flexors and extensors tendons in the microscopical study

    Nailfold Capillaroscopy and Autoimmune Connective Tissue Diseases in Patients From a Portuguese Nailfold Capillaroscopy Clinic

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    Raynaud's phenomenon (RP) is frequent in autoimmune connective tissue diseases (AICTD) and its approach includes nailfold capillaroscopy (NFC), as it is a non-invasive technique that permits direct visualization of the microcirculation. The aim of this study is to analyze and establish clinical correlations between NFC findings and particular aspects of autoimmune disorders. This is a retrospective study. Clinical data from patients attending our NFC clinic were reviewed. Inclusion criteria included AICTD previous diagnosis, which included systemic sclerosis (SSc), mixed connective tissue disease (MCTD), systemic lupus erythematosus (SLE), Sjögren syndrome, inflammatory idiopathic myopathies (IIM), rheumatoid arthritis, undifferentiated connective tissue disease and antiphospholipid syndrome (APS). Videocap® version 3.0 biomicroscope was used. NFC score was determined. For statistics, SPSS software was utilized. 384 patients were included; most of them were women, with mean age of 47 years. RP was present in 91% of the patients, with greater prevalence in SSc and MCTD. Scleroderma pattern was the most prevalent NFC pattern, mainly in SSc, MCTD and IIM. Mean capillary density was reduced in IIM, SSc and MCTD. NFC score was worse in SSc, IIM and MCTD. In patients with AICTD, RP is related to microvascular damage and worse NFC score. NFC scleroderma pattern correlates with SSc classification criteria score. In MCTD, scleroderma pattern relates to myositis. SLE and APS reveal significant hemorrhages, but not related to APS antibodies. This study highlights the possible role of NFC as biomarker of AICTD, particularly in SSc and IIM.info:eu-repo/semantics/publishedVersio

    Systemic Mastocytosis - a Diagnostic Challenge

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    Mastocytosis refers to a group of disorders characterized by the infiltration of clonally derived mast cells to the skin or extracutaneous tissues resulting in a heterogeneous clinical picture. It is a rare hematologic disorder in all its forms. The exact incidence is unknown; it affects patients of any age and males and females equally. Its molecular pathogenesis is incompletely understood. The clinical features of mastocytosis result from both chronic and episodic mast cell mediator release, signs and symptoms arising from diffuse or focal tissue infiltration, and, occasionally, the presence of an associated non-mast cell clonal hematologic disease. The histopathologic analysis is essential for definitive diagnosis but there is no curative treatment. The authors report a clinical case of a 72-year-old woman with no history of allergies, with bicytopenia, weight loss, and diffuse axial osteolytic lesions. This is a rare clinical case of aggressive systemic mastocytosis for which palliative treatment can improve survival and quality of life. A brief review of the literature about this pathology is also included

    Characterization and immunolocalization of a main proteinaceous component of the cell wall of the protozoan parasite Perkinsus atlanticus

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    Described in the present study is a major component of the cell wall of two of the most pathogenic parasites of molluscs, Perkinsus atlanticus and P. marinus. The component is a high-molecular-weight protein (233-kDa), which we have named PWP-1 (for Perkinsus wall protein-1). Western blots, using a polyclonal serum generated against purified PWP-1 from P. atlanticus, revealed that this protein is expressed by all walled developmental stages of this protozoon. By means of immunogold electron microscopy, labelling for PWP-1 was strong and specifically associated with the cell wall. The label density and distribution pattern was quite different between trophozoites and prezoosporangia. With regard to the structural organization of this protein, PWP-1 is disulphide-linked to other cell wall components and released from the cell wall only following treatment with a sulfhydryl agent. We also report that PWP-1 is a trypsin-resistant protein, both in its native and heat-denatured conformation. In addition, results from the N-terminal microsequence of this protein allow us to define PWP-1 as a novel cell wall protein. Overall, our findings strongly suggest that PWP-1 plays a key role in the organization of the cell wall of these protozoa promoting their survival

    ECONOMÍA DEL CONOCIMIENTO Y TRANSFORMACIÓN DE LOS MERCADOS LABORALES: IMPLICACIONES PARA LAS ORGANIZACIONES UNIVERSITARIAS.

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    La Universidad como organización sustantiva de la sociedad no puede ni debe permanecer ajena a los cambios que se presentan en su entorno. En este sentido, la evolución de las economías centradas en el capital material hacia las centradas en el conocimiento ha traído consigo un conjunto de transformaciones en el orden económico, social y laboral. En este marco, la presente comunicación tiene como objeto compartir un conjunto de reflexiones en torno a cómo la Universidad como organización puede dar respuesta a los retos que emanan de la economía y sociedad del conocimiento en forma particular: en sus formas de relación con el entorno, en su vinculación con los mercados laborales y nuevas culturas de trabajo, en el uso ético y racional de las tecnologías, en el reconocimiento y respeto a las diferencias culturales e ideológicas, y a su interior, en sus estructuras organizacionales, académicas y de gestión

    Electron effective mass and mobility in heavily doped n-GaAsN probed by Raman scattering

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    We investigate inelastic light scattering by longitudinal optic phonon-plasmon coupled modes LOPCMs in a series of heavily Se-doped, n-type GaAs1−xNx epilayers with x 0.4%. We perform a line shape analysis of the LOPCM spectra to estimate the optical effective mass, mopt , and the scattering time of the conduction electrons in GaAsN. We use these results to evaluate an effective carrier mobility for our samples. The values thus obtained, which we compare with measured electron Hall mobilities, indicate that the x-dependence of the mobility in GaAs1−xNx is dominated by the scattering time, rather than by the variation of the electron effective mass. The Raman analysis yields mopt values that are lower than those obtained from the band anticrossing model. © 2008 American Institute of Physics.This work is supported by the Spanish Government Projects MAT 2004-0664 and MAT2007-63617, and Ramon y Cajal Program and the EPSRC, United Kingdom. 1M. Henini, Dilute Nitride Semiconductors Elsevier Science, AmsterdamPeer reviewe
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