Canonical approach to the closed string noncommutativity

We consider the closed string moving in the weakly curved background and its totally T-dualized background. Using T-duality transformation laws, we find the structure of the Poisson brackets in the T-dual space corresponding to the fundamental Poisson brackets in the original theory. From this structure we obtain that the commutative original theory is equivalent to the non-commutative T-dual theory, whose Poisson brackets are proportional to the background fluxes times winding and momenta numbers. The non-commutative theory of the present article is more nongeometrical then T-folds and in the case of three space-time dimensions corresponds to the nongeometric space-time with $R$-flux.Comment: We add the Sec. 4. where we compared our results with previous ones. We also improved Abstract, Introduction and Conclusion as described above. In addition, we corrected all typos and grammatical errors we notice

Efeitos da reabilitação precoce no desfecho da reabilitação pós-acidente vascular encefálico (AVE) em mulheres com mais de 65 anos e sua correlação com a gravidade do deficit neurológico inicial

Este trabalho visa examinar os efeitos da reabilitação precoce, a curto e longo prazo, no desfecho do acidente vascular encefálico (AVE) em mulheres com mais de 65 anos; estabelecer a correlação entre o impacto da gravidade do déficit neurológico na predição dos re-sultados do tratamento de Reabilitação e, ainda, investigar a possibilidade do acompanhamento de parâmetros individuais da Medição de Independência Funcional (MIF) na predição do desfecho da reabilitação do AVE. Atualmente, o AVE é a terceira maior causa de mortalidade na população mundial, bem como a maior causa de invalidez permanente. No cenário atual, as doenças cardiovasculares e cerebrovasculares - que antes eram tidas como exclusivas da população masculina – têm afetado também as mulheres. Por outro lado, observamos uma correlação linear entre o envelhecimento e a ocorrência destas doenças. Concluímos que a implantação do método de reabilitação precoce conduz a uma aceleração significativa do processo de tratamento e recuperação após o AVE em mulheres com mais de 65 anos. Concluímos também que certos parâmetros da MIF, por apresentarem o mesmo padrão de evolução, podem ser utilizados na predição da recuperação global do paciente.This study aims at verifying the effects of short- and long-term rehabilitation on the outcome of encephalic vascular accident (EVA) in women older than 65 years; establishing the correlation between the impact of the neurological deficit severity on the prediction of the rehabilitation treatment outcome as well as investigating the possibility of the follow-up of individual parameters at the Functional Independence Measure (FIM) when predicting the EVA rehabilitation outcome. The EVA is currently the third major cause of death in the world’s population, as well as the main cause of permanent disability. In the present scenario, cardiovascular and cerebrovascular diseases, which used to be observed almost exclusively in the male population, now affect the female population as well. On the other hand, we observe a linear correlation between aging and the occurrence of these diseases. We conclude that the implementation of early rehabilitation leads to a significant acceleration in the treatment and recovery process post-EVA in women older than 65 years. We also conclude that certain FIM parameters can be used to predict the patient’s overall recovery, as they present the same evolution pattern

Frequency of Electrocardiographic Changes in Trained Athletes in the Republic of Macedonia

BACKGROUND: The use of a 12-lead electrocardiogram (ECG) in the screening of young athletes still has some controversies regarding the cost-benefit of the procedure.AIM: We wanted to identify types and frequency of ECG changes in athletes in the Republic of Macedonia as well as its relation to age, gender, duration, frequency and type of sports.METHODS: The study population included 256 trained amateur athletes who were prospectively examined.RESULTS: The 12-lead ECG patterns were considered normal in 19.9% of athletes, with common training-related changes found in 48.8%, while abnormal and borderline ECG changes were present in 6.6% and 24.6% of athletes respectively. ECG changes were more frequent in males than in females without significant difference regarding the age of athletes. There was a significant correlation between more pronounced ECG changes and longer duration of sports engagement, higher duration of sports activity and type of sport practised.CONCLUSION: The prevalence of abnormal ECG patterns in athletes in RM which could indicate structural cardiac disease and greater risk of sudden cardiac death exist in a proportion that should implicate mandatory 12-lead ECG in the pre-participation screening program and further on the regular annual basis

Glutathione redox cycle in small intestinal mucosa and peripheral blood of pediatric celiac disease patients

The celiac disease is an autoimmune gastrointestinal disorder caused by gluten from wheat, rye or barley. In genetically predisposed persons, gluten induces the immune-mediated inflammation of small intestinal mucosa. Histological lesions include intraepithelial lymphocytosis, crypt hypertrophy and villous atrophy, resulting in malabsorption of micro- and macronutrients. The only treatment for celiac patients is a permanent gluten-free diet (GFD). Reactive oxygen species (ROS) and oxidative stress are strongly associated with the celiac disease. Glutathione (GSH) is a main detoxifier of endogenous and exogenous ROS in the intestine. In order to explain the role of glutathione redox cycle in celiac patients, we examined the activities of GSH-related antioxidant (AO) enzymes glutathione peroxidase (GPx) and glutathione reductase (GR), as well as the concentration of GSH in small intestinal biopsies and peripheral blood of children affected by the celiac disease. The concentration of lipid hydroperoxides (LOOH) as markers of oxidative damage was measured in the same samples. The results clearly demonstrate a significant malfunction of GSH redox cycle with a concomitant decrease in the capacity to regenerate GSH and detoxify LOOH in celiac patients, even after several years of GFD. The oral administration of GSH and a diet rich in natural antioxidants, as well as appropriate dietary supplements, could be of great benefit to the patients

Vaaisible upconversion emission of Er3+-doped and Er3+/Yb3+-codoped LiInO2

Lithium-indium oxide is a high-density (5.9 g center dot cm(-3)), wide band-gap semiconductor with promising applications for scintillating detection of solar neutrinos as well as for efficient phosphorescence when doped with Er3+ or Sm3+ ions. In this report, we demonstrate visible upconversion emission of Er3+-doped LiInO2 synthesized by a simple solid-state chemistry procedure and discuss mechanisms responsible for pumping the Er3+ ions to upper levels. Intense upconversion emission is observed in the green and red spectral regions under near-infrared excitation, and it is greatly enhanced by co-doping with Yb3+ ions. We also examined the upconversion intensity change as a function of temperature, and, consequently, possible applications of this material as a low-temperature sensor

Disseminated Neonatal Herpes Caused by Herpes Simplex Virus Types 1 and 2

Disseminated neonatal herpes simplex virus (HSV) infection is characterized by progressive multiple organ failure and high mortality rates. It can result from infection with either HSV-1 or HSV-2. We report a case of disseminated neonatal herpes that was caused by HSV-1 and HSV-2

Gal-3 plays an important pro-inflammatory role in the induction phase of acute colitis by promoting activation of NLRP3 inflammasome and production of IL-β in macrophages

BACKGROUND AND AIMS: Galectin-3 [Gal-3] is an endogenous lectin with a broad spectrum of immunoregulatory effects: it plays an important role in autoimmune/inflammatory and malignant diseases, but the precise role of Gal-3 in pathogenesis of ulcerative colitis is still unknown. METHODS: We used a model of dextran sulphate sodium [DSS]-induced acute colitis. The role of Gal-3 in pathogenesis of this disease was tested by evaluating disease development in Gal-3 deficient mice and administration of Gal-3 inhibitor. Disease was monitored by clinical, histological, histochemical, and immunophenotypic investigations. Adoptive transfer was used to detect cellular events in pathogenesis. RESULTS: Genetic deletion or pharmacological inhibition of Gal-3 significantly attenuate DSS-induced colitis. Gal-3 deletion suppresses production of pro-inflammatory cytokines in colonic macrophages and favours their alternative activation, as well as significantly reducing activation of NOD-like receptor family, pyrin domain containing 3 [NLRP3] inflammasome in macrophages. Peritoneal macrophages isolated from untreated Gal-3(-/-) mice and treated in vitro with bacterial lipopolysaccharide or DSS produce lower amounts of tumour necrosis factor alpha [TNF-α] and interleukin beta [IL-1β] when compared with wild type [WT] cells. Genetic deletion of Gal-3 did not directly affect total neutrophils, inflammatory dendritic cells [DCs] or natural killer [NK] T cells. However, the total number of CD11c+ CD80+ DCs which produce pro-inflammatory cytokines, as well as TNF-α and IL-1β producing CD45+ CD11c- Ly6G+ neutrophils were significantly lower in colons of Gal-3(-/-) DSS-treated mice. Adoptive transfer of WT macrophages significantly enhanced the severity of disease in Gal-3(-/-) mice. CONCLUSIONS: Gal-3 expression promotes acute DSS-induced colitis and plays an important pro-inflammatory role in the induction phase of colitis by promoting the activation of NLRP3 inflammasome and production of IL-1β in macrophages

SELBSTVERSORGUNG – ZWISCHEN LIFESTYLE UND ERNÄHRUNGSSICHERUNG?

Der Anbau von Lebensmitteln im heimischen Garten, auf Pachtflächen, in Schrebergärten oder Communal Gardens erfreut sich ungeahnter Beliebtheit. Neuere empirische Arbeiten weisen darauf hin, dass Obst- und Gemüseanbau, Kleintierhaltung und Hausschlachtungen jenseits der großstädtischen Lifestyle-Mode für viele Menschen im ländlichen Raum wieder an Bedeutung gewinnen. Das Forschungsprojekt "Selbstversorgung - ein Beitrag zur Ernährungssicherung" an der Hochschule Niederrhein untersucht, ob Selbstversorgung in Zeiten verschärften demographischen Wandels und ökonomischer Krisen, die Versorgungslage, vor allem ländlicher Haushalte, stabilisieren kann

Modification of TiO2 nanoparticles through lanthanum doping and PEG templating

Pure and lanthanum doped titania nanopowders were synthesized through a room temperature sol-gel method using a template of polyethylene glycol (PEG). The progress of the synthesis in terms of phase formation and size of nanoparticles was monitored by X-ray diffraction, FTIR spectroscopy and SEM analysis. After calcination at 450 °C in air, the results have shown the presence of small particles crystallized predominantly in the form of anatase phase, with significant agglomeration. Nitrogen adsorption-desorption measurements confirmed that all prepared powders are mesoporous with an average pore diameter in range 3.1–3.8 nm. The addition of lanthanum ions leads to the nanopowders with the highest specific surface (BET) area (203 m2/g). The obtained powders were compared to TiO2 prepared without a template

Effect of temperature on the electrodeposition of disperse copper deposits

The effect of temperature on the electrodeposition of copper at overpotentials belonging to the plateau of the limiting diffusion current density and higher was examined by the determination of the average current efficiency of hydrogen evolution and by scanning electron microscopic (SEM) analysis of the morphology of the formed copper deposits. Increasing the temperature of the solution led to a shift of both the beginning and the end of the plateau of the limiting diffusion current density towards lower electrodeposition overpotentials. Also, higher temperatures led to the formation of morphological forms of copper deposits characteristic for electrodeposition of copper at some higher overpotentials. The unexpected trend in the development of copper structures electrodeposited at an overpotential of 800 mV is discussed in terms of the effect of temperature on the viscosity and surface tension of the electroplating solution.Uticaj temperature na elektrohemijsko taloženje bakra na prenapetostima koje pripadaju platoima granične difuzione gustine struje, kao i na višim prenapetostima je ispitan određivanjem srednjeg iskorišćenja struje reakcije izdvajanja vodonika i analizom morfologija taloga bakra tehnikom skenirajuće elektronske mikroskopije. Povećanje temperature rastvora dovelo je do pomeranja i početka i kraja platoa granične difuzione gustine struje ka nižim prenapetostima. Takođe, povećanje temperature dovelo je do formiranja morfoloških formi taloga bakra karakterističnih za elektrohemijsko taloženje na nekim višim prenapetostima. Neočekivani trend u razvoju struktura bakra dobijenih na prenapetosti od 800 mV je bio diskutovan na osnovu uticaja temperature na viskoznost i površinski napon rastvora za elektrohemijsko taloženje bakra