Segmentation of Kidney and Renal Tumor in CT Scans Using Convolutional Networks

Accurate segmentation of kidney and renal tumor in CT images is a prerequisite step in surgery planning. However, this task remains a challenge. In this report, we use convolutional networks (ConvNet) to automatically segment kidney and renal tumor. Specifically, we adopt a 2D ConvNet to select a range of slices to be segmented in the inference phase for accelerating segmentation, while a 3D ConvNet is trained to segment regions of interest in the above narrow range. In localization phase, CT images from several publicly available datasets were used for learning localizer. This localizer aims to filter out slices impossible containing kidney and renal tumor, and it was fine-tuned from AlexNet pre-trained on ImageNet. In segmentation phase, a simple U-net with large patch size (160×160×80) was trained to delineate contours of kidney and renal tumor. In the 2019 MICCAI Kidney Tumor Segmentation (KiTS19) Challenge, 5-fold cross-validation was performed on the training set. 168 (80%) CT scans were used for training and remaining 42 (20%) cases were used for validation. The resulting average Dice similarity coefficients are 0.9662 and 0.7905 for kidney and renal tumor, respectively

Devices and methods for wet gas flow metering: a comprehensive review

Wet gas is commonly encountered in various industries, including energy, chemical, and electric power sectors. For example, natural gas extracted from production often contains small amounts of liquid, such as water and hydrocarbon condensates, which classifies it as wet gas. The presence of liquid within the gas poses challenges for accurate flow measurement. To improve the performances of wet gas flow metering methods, significant research and development efforts have been invested into the wet gas flow metering technologies due to their vital importance in the production, transfer, and trade benefits. This paper presents a comprehensive overview of the recent development of wet gas flow metering. Firstly, a comprehensive discussion of the Lockhart-Martinelli parameter (Xlm) and its relation to the gas void fraction (Óg) is presented, which was mostly overlooked in previous wet gas research work. The occurrence of various flow patterns in wet gas conditions at different orientations (horizontal and vertical) was explored. Following an investigation of pressure impact on the wet gas flow patterns and development of the wet gas regions, a different test matrix for further research work was suggested. After a novel classification of wet gas measurement methods, the paper offers a detailed comparison of differential pressure (DP) meters including Venturi, Cone meter, and orifice meters, by considering both liquid and gas flow rate measurements. Secondly, the paper discusses and compares vortex flow meters, Coriolis and ultrasonic meters in comparison to DP meters. Notable phase fraction meters are also examined and compared to one another. Thirdly, the paper reviewed the concept of existing and potential hybrid wet gas meters, conducting a detailed discussion and comparison with commercial solutions by evaluating their ranges and accuracies. This assessment provides valuable insights into the capabilities of these hybrid meters, highlighting their potential to enhance the measurement of wet gas flow rates

Integrated dielectric model for unconsolidated porous media containing hydrate

This article reports a novel dielectric model developed for estimating the complex permittivity of unconsolidated porous media containing gas hydrate. The complex permittivity spectra were experimentally obtained by using open-ended-coaxial-probes over a frequency range between 1 MHz and 3 GHz, in which the dielectric dispersion of both hydrate and liquid solution are covered. With tetrahydrofuran used as the hydrate former, reflection coefficients were recorded during the hydrate formation and dissociation processes in quartz sands and the complex permittivity spectra were inversed. Volumetric fractions estimated from the X-ray-tomography were used as the referenced values. Experimental data showed that the Maxwell-Wagner effect, surface conductance, and phase configuration can affect the bulk permittivity. The discrepancy was found to be unacceptable when the fitting was conducted with pre-existing models such as complex-refractive-index-method (CRIM) and Maxwell-Wagner-Bruggeman-Hanai (MWBH). In this study, by modifying the nested Wagner's theory, a shell-coated model was applied, and the surface of the solid sphere was assumed to possess surface conductance when it was humidified by the liquid solution. In contrast to CRIM and MWBH, the proposed model allows more accurate estimation of the volumetric fraction. By adopting this model with a range of dielectric measurements with different phase configurations, temperature, particle size, surface conductivity, and frequency, the contents of components and their influences onto the bulk permittivity can be physically estimated. The proposed model provides an essential tool for the interpretation of dielectric dispersion curves and the prediction of the volumetric fractions, which can be useful for both the field and laboratory applications

Quantitative analysis of guided wave in dielectric logging through numerical simulation

A good knowledge of the electromagnetic (EM) wave propagation behaviors in dielectric logging (DL) and borehole radar (BHR) surveying is critically important for the optimization of tool design and implementation, and interpretation of the acquired logging data, as well as understanding the influences of the dielectric permittivity and conductivity of the formation on the EM waves. This letter reported a novel method for the numerical simulation and analysis of the guided wave (GW) propagating along a metallic pipe in a typical DL configuration. A numerical simulation with the 3-D finite-difference time-domain (FDTD) method was applied to the broadband DL tool to obtain the wavefield and responses of the receiver. By monitoring the wave attenuation along the metallic drill collar, the intensity of the GW and loss factor can be determined. The coupling efficiency of the GW can be obtained when the total power emitted from the transmitting antenna is known. Simulation results revealed that the coupling efficiency of the GW changes with the water saturation of the formation and frequency. The simulation also suggest, by installing a slope structure adjacent to the transmitting antenna, the energy coupled into the GW could be reduced at different levels. Finally, the relationship between the received signals' amplitude and GW's coupling efficiency showed the quantified contribution of the GW to the received sign

Assessing Heavy Metal Pollution of the Largest Nature Reserve in Tianjin City, China

Embargo until June 10, 2023Beidagang Wetland (BW) Nature Reserve is centrally situated in Tianjin City, experiencing an extreme industrial development. This study uses index characteristic analysis systems for assessing the individual and combined heavy metal pollution loading in the water during the spring and autumn seasons. By combining the pollution level of single pollutant, a more comprehensive evaluation of water quality in BW was achieved. Water quality was worst during autumn due to high level of Cd and Pb, which indicate the type of anthropogenic activities have a serious effect on heavy metal pollution in BW. In addition, high exchangeable amounts of Cd (> 40%) were found in the sediments of BW, indicating Cd pollution has emerged. There is a need for appropriate abatement actions curbing heavy metal loading and improving water quality of the BW Nature Reserve, thereby ensuring a sustainable management of its ecosystem services.acceptedVersio

Numerical study on complex conductivity characteristics of hydrate-bearing porous media

The complex conductivity method is frequently used in hydro-/petro-/environmental geophysics, and considered to be a promising tool for characterizing and quantifying the properties of subsurface rocks, sediments and soils. We report a study on the complex conductivity characteristics of porous media containing gas hydrates through numerical modelling. The effects of the hydrate saturation, pore-water salinity and micro-distribution mode were studied, and hydrate-saturation evaluation correlations based on complex conductivity parameters were developed. A pore-scale numerical approach for developing the finite-element based models for hydrate-bearing porous media is proposed and a two-dimensional (2D) model is built to compute the complex conductivity responses of porous media under various conditions. We demonstrate that the simple 2D model can capture the dominant characteristics of the complex conductivity of hydrate-bearing porous media within the frequency range related to the induced polarization. The in-phase conductivity, quadrature conductivity and effective dielectric constant can be correlated with the saturation based on a power law in the log-log space, by which the hydrate-saturation evaluation models can be derived. A constant saturation exponent of the power-law correlation between the hydrate saturation and quadrature conductivity can be obtained when the pore-water conductivity exceeds 1.0 S/m. This is highly desirable in the hydrate-saturation models due to the variations of the pore-water conductivity in the processes of hydrate formation and dissociation. Within the framework of the complex conductivity analysis, the micro-distribution modes of hydrates in porous media can be categorized into two types. These are the fluid-suspending mode and grain-attaching mode. The in-phase conductivity exhibits significant variations under the same saturation and salinity but different micro-distribution modes, which can be attributed to the change in the tortuosity of the electrical conduction paths in the void space of porous media

Actively implementing an evidence-based feeding guideline for critically ill patients (NEED): a multicenter, cluster-randomized, controlled trial

Background: Previous cluster-randomized controlled trials evaluating the impact of implementing evidence-based guidelines for nutrition therapy in critical illness do not consistently demonstrate patient benefits. A large-scale, sufficiently powered study is therefore warranted to ascertain the effects of guideline implementation on patient-centered outcomes. Methods: We conducted a multicenter, cluster-randomized, parallel-controlled trial in intensive care units (ICUs) across China. We developed an evidence-based feeding guideline. ICUs randomly allocated to the guideline group formed a local "intervention team", which actively implemented the guideline using standardized educational materials, a graphical feeding protocol, and live online education outreach meetings conducted by members of the study management committee. ICUs assigned to the control group remained unaware of the guideline content. All ICUs enrolled patients who were expected to stay in the ICU longer than seven days. The primary outcome was all-cause mortality within 28 days of enrollment. Results: Forty-eight ICUs were randomized to the guideline group and 49 to the control group. From March 2018 to July 2019, the guideline ICUs enrolled 1399 patients, and the control ICUs enrolled 1373 patients. Implementation of the guideline resulted in significantly earlier EN initiation (1.20 vs. 1.55 mean days to initiation of EN; difference − 0.40 [95% CI − 0.71 to − 0.09]; P = 0.01) and delayed PN initiation (1.29 vs. 0.80 mean days to start of PN; difference 1.06 [95% CI 0.44 to 1.67]; P = 0.001). There was no significant difference in 28-day mortality (14.2% vs. 15.2%; difference − 1.6% [95% CI − 4.3% to 1.2%]; P = 0.42) between groups. Conclusions: In this large-scale, multicenter trial, active implementation of an evidence-based feeding guideline reduced the time to commencement of EN and overall PN use but did not translate to a reduction in mortality from critical illness. Trial registration: ISRCTN, ISRCTN12233792. Registered November 20th, 2017

Actively implementing an evidence-based feeding guideline for critically ill patients (NEED): a multicenter, cluster-randomized, controlled trial.

BackgroundPrevious cluster-randomized controlled trials evaluating the impact of implementing evidence-based guidelines for nutrition therapy in critical illness do not consistently demonstrate patient benefits. A large-scale, sufficiently powered study is therefore warranted to ascertain the effects of guideline implementation on patient-centered outcomes.MethodsWe conducted a multicenter, cluster-randomized, parallel-controlled trial in intensive care units (ICUs) across China. We developed an evidence-based feeding guideline. ICUs randomly allocated to the guideline group formed a local "intervention team", which actively implemented the guideline using standardized educational materials, a graphical feeding protocol, and live online education outreach meetings conducted by members of the study management committee. ICUs assigned to the control group remained unaware of the guideline content. All ICUs enrolled patients who were expected to stay in the ICU longer than seven days. The primary outcome was all-cause mortality within 28 days of enrollment.ResultsForty-eight ICUs were randomized to the guideline group and 49 to the control group. From March 2018 to July 2019, the guideline ICUs enrolled 1399 patients, and the control ICUs enrolled 1373 patients. Implementation of the guideline resulted in significantly earlier EN initiation (1.20 vs. 1.55 mean days to initiation of EN; difference - 0.40 [95% CI - 0.71 to - 0.09]; P = 0.01) and delayed PN initiation (1.29 vs. 0.80 mean days to start of PN; difference 1.06 [95% CI 0.44 to 1.67]; P = 0.001). There was no significant difference in 28-day mortality (14.2% vs. 15.2%; difference - 1.6% [95% CI - 4.3% to 1.2%]; P = 0.42) between groups.ConclusionsIn this large-scale, multicenter trial, active implementation of an evidence-based feeding guideline reduced the time to commencement of EN and overall PN use but did not translate to a reduction in mortality from critical illness.Trial registrationISRCTN, ISRCTN12233792 . Registered November 20th, 2017

Actively implementing an evidence-based feeding guideline for critically ill patients (NEED): a multicenter, cluster-randomized, controlled trial (vol 26, 46, 2022)

BackgroundPrevious cluster-randomized controlled trials evaluating the impact of implementing evidence-based guidelines for nutrition therapy in critical illness do not consistently demonstrate patient benefits. A large-scale, sufficiently powered study is therefore warranted to ascertain the effects of guideline implementation on patient-centered outcomes.MethodsWe conducted a multicenter, cluster-randomized, parallel-controlled trial in intensive care units (ICUs) across China. We developed an evidence-based feeding guideline. ICUs randomly allocated to the guideline group formed a local "intervention team", which actively implemented the guideline using standardized educational materials, a graphical feeding protocol, and live online education outreach meetings conducted by members of the study management committee. ICUs assigned to the control group remained unaware of the guideline content. All ICUs enrolled patients who were expected to stay in the ICU longer than seven days. The primary outcome was all-cause mortality within 28 days of enrollment.ResultsForty-eight ICUs were randomized to the guideline group and 49 to the control group. From March 2018 to July 2019, the guideline ICUs enrolled 1399 patients, and the control ICUs enrolled 1373 patients. Implementation of the guideline resulted in significantly earlier EN initiation (1.20 vs. 1.55 mean days to initiation of EN; difference - 0.40 [95% CI - 0.71 to - 0.09]; P = 0.01) and delayed PN initiation (1.29 vs. 0.80 mean days to start of PN; difference 1.06 [95% CI 0.44 to 1.67]; P = 0.001). There was no significant difference in 28-day mortality (14.2% vs. 15.2%; difference - 1.6% [95% CI - 4.3% to 1.2%]; P = 0.42) between groups.ConclusionsIn this large-scale, multicenter trial, active implementation of an evidence-based feeding guideline reduced the time to commencement of EN and overall PN use but did not translate to a reduction in mortality from critical illness.Trial registrationISRCTN, ISRCTN12233792 . Registered November 20th, 2017