Effects of the wide-body suspension bridge auxiliary structure on flutter characteristics by CFD

This paper is focused on the CFD numerical simulation of flutter characteristics of the wide-body flat steel box girder of Chongqing Cuntan Yangtze Bridge. The specific influence on the aerodynamic performance and flutter critical wind velocity have been studied by setting different railing ventilation rates. The results show that: the subsidiary structures of the main beam have an adverse effect on the stability of bridge flutter. The ventilation rate of the railings affects the flutter derivatives and the critical wind speed of the flutter

Global method for a class of operation optimization problem in steel rolling systems

Many steel products are produced in hot or cold rolling lines with multiple stands. The steel material becomes thinner after being rolled at each stand. Steady-state parameters for controlling the rolling line need to be set so as to satisfy the final product specifications and minimize the total energy consumption. This paper develops a generalized geometric programming model for this setting problem and proposes a global method for solving it. The model can be expressed with a linear objective function and a set of constraints including nonconvex ones. Through constructing lower bounds of some components, the constraints can be converted to convex ones approximately. A sequential approximation method is proposed in a gradually reduced interval to improve accuracy and efficiency. However, the resulting convex programming model in each iteration is still complicated. To reduce the power, it is transformed into a second-order cone programming (SOCP) model and solved using alternating direction method of multipliers (ADMM). The effectiveness of the global method is tested using real data from a hot-rolling line with seven stands. The results demonstrate that the proposed global method solves the problem effectively and reduces the energy consumption

The influence of survivin shRNA on the cell cycle and the invasion of SW480 cells of colorectal carcinoma

<p>Abstract</p> <p>Background</p> <p>The objective was to understand the influence of Survivin plasmid with short hairpin RNA (shRNA) on the cell cycle, invasion, and the silencing effect of Survivin gene in the SW480 cell of colorectal carcinoma.</p> <p>Methods</p> <p>A eukaryotic expression vector, PGCH1/Survivin shRNA, a segment sequence of Survivin as target, was created and transfected into colorectal carcinoma cell line SW480 by the non-lipid method. The influence on the Survivin protein was analyzed by Western blotting, while the cell cycle, cell apoptosis were analyzed by flow cytometry, and invasion of the cell was analyzed by Transwell's chamber method.</p> <p>Results</p> <p>After the transfection of PGCH1/Survivin shRNA, the expression of Survivin protein in SW480 cells was dramatically decreased by 60.68%, in which the cells were stopped at G2/M phase, even though no apoptosis was detected. The number of transmembranous cells of the experimental group, negative control group, and blank control group were 14.46 ± 2.11, 25.12 ± 8.37, and 25.86 ± 7.45, respectively (P <<it>0.05</it>).</p> <p>Conclusion</p> <p>Survivin shRNA could significantly reduce the expression of Survivin protein and invasion of SW480 cells. Changes in cell cycle were observed, but no apoptosis was induced.</p

Aerodynamic admittance influence on buffeting performance of suspension bridge with streamlined deck

Buffeting performance is growing sensitive to external and internal factors with increasing span of bridge. Aerodynamic admittance is an essential parameter in analyzing buffeting performance. In this paper, aerodynamic admittance in different conditions were conducted in wind tunnel tests by section model. Three kinds of aerodynamic admittance functions were used to calculating buffeting performance respectively. It is found that the aerodynamic admittance of streamlined deck is closely related to wind attack angle, and has a small difference at different wind speeds. However, the influence of aerodynamic admittance on buffeting performance is affected by the wind speed significantly. Under given conditions, adopting the Sears function as the admittance function of a similar streamlined box girder is reasonable, while the buffeting performance result obtained by adopting an admittance function as 1.0 is very conservative

Investigation and Control of VIVs with Multi-Lock-in Regions on Wide Flat Box Girders

On the preliminary designing of a wide flat box girder with the slenderness ratio 12, vertical and torsional vortex-induced vibrations (VIV) are observed in wind tunnel tests. More than one lock-in region, which are defined as “multi-lock-in regions,” are recorded. Therefore, suspicions should be aroused regarding the viewpoint that wide box girders are aerodynamic friendly. As the three nascent vortexes originating at the pedestrian guardrails and inspection rails shed to near-wake through different pathways with different frequencies, the mechanisms of VIVs and multi-lock-in regions are analyzed to be determined by the inappropriate subsidiary structures. A hybrid method combining Large Eddy Simulation (LES) with experimental results is introduced to study the flow-structure interactions (FSI) when undergoing VIVs; the vortex mode of torsional VIV on wide flat box girders is defined as “4/2S,” which is different from any other known ones. Based on the mechanism of VIV, a new approach by increasing ventilation rate of the pedestrian guardrails is proved to be effective in suppressing vertical and torsional VIVs, and it is more feasible than other control schemes. Then, the control mechanisms are deeper investigated by analyzing the evolution of vortex mode and FSI using Hybrid-LES method

Mesoporous TiO

Mesoporous anatase TiO2 micro-nanometer composite structure was synthesized by solvothermal method at 180°C, followed by calcination at 400°C for 2 h. The as-prepared TiO2 was characterized by X-ray diffraction (XRD), scanning electron microscope (SEM), transmission electron microscope (TEM), and Fourier transform infrared spectrum (FT-IR). The specific surface area and pore size distribution were obtained from N2 adsorption-desorption isotherm, and the optoelectric property of the mesoporous TiO2 was studied by UV-Vis absorption spectrum and surface photovoltage spectra (SPS). The photocatalytic activity was evaluated by photodegradation of sole rhodamine B (RhB) and sole phenol aqueous solutions under simulated sunlight irradiation and compared with that of Degussa P-25 (P25) under the same conditions. The photodegradation preference of this mesoporous TiO2 was also investigated for an RhB-phenol mixed solution. The results show that the TiO2 composite structure consists of microspheres (∼0.5–2 μm in diameter) and irregular aggregates (several hundred nanometers) with rough surfaces and the average primary particle size is 10.2 nm. The photodegradation activities of this mesoporous TiO2 on both RhB and phenol solutions are higher than those of P25. Moreover, this as-prepared TiO2 exhibits photodegradation preference on RhB in the RhB-phenol mixture solution

Retrospective analysis of 217 fatal intoxication autopsy cases from 2009 to 2021: temporal trends in fatal intoxication at Tongji center for medicolegal expertise, Hubei, China

This retrospective analysis of fatal intoxication case autopsies was performed at Tongji Center for Medicolegal Expertise in Hubei (TCMEH) from 2009 to 2021 to obtain up-to-date information on intoxication cases. The objective was to describe important data about evolving patterns in intoxication occurrences, enhance public safety policies, and assist forensic examiners and police in more efficient handling of such cases. Analyses based on sex, age, topical exposure routes, toxic agents, and mode of death were performed using 217 records of intoxication cases collected from TCMEH as a sample, and the results were compared with reports previously published (from 1999 to 2008) from this institution. Deaths from intoxications occurred at a higher rate in males than in females and were most common among individuals aged 30–39 years. The most frequent method of exposure was oral ingestion. The causative agents of deadly intoxications have changed when compared to the data from the previous 10 years. For instance, deaths from amphetamine overdoses are becoming more prevalent gradually, whereas deaths due to carbon monoxide and rodenticide intoxication have declined dramatically. In 72 cases, pesticides continued to be the most frequent intoxication cause. A total of 60.4% of the deaths were accidental exposure. Men died from accidents at a higher rate than women, although women were more likely to commit suicide. Particular focus is needed on the use of succinylcholine, cyanide, and paraquat in homicides

Analyzing Ionosphere TEC and ROTI Responses on 2010 August High Speed Solar Winds

The high-speed solar winds stream (HSSWS) generated by coronal hole can produce large interplanetary magnetic field magnitude oscillations, leading to high latitude geomagnetic disturbances, and ionospheric responses as well. This paper has analyzed the global ionospheric total electron content (TEC) and rate of TEC index (ROTI) responses during the high speed solar winds stream occurred from 23 to 29 August, 2010. Ground Global Navigation Satellite System (GNSS) network was mainly used to investigate ionosphere TEC and ROTI behaviors. It has revealed that high latitudes and middle latitudes ionosphere suffered most during this event, with hemisphere asymmetry characteristics. Both TEC variations and ionosphere irregularities were analyzed. The HSSWS event brings to strong ionosphere irregularities represented by large ROTI enhancements at high latitudes. The concentrated ionosphere irregularities were closely related to the intensity of Auroral Electrojet enhancement activities. The ROTI enhancements at high latitudes, including polar cap, aurora, and sub-aurora are also influenced by solar zenith angle; all the prominent ROTI increments are observed in the ranges between 70° and 110° solar zenith angles; while the ROTI enhancements at low latitudes and equator are mostly found in the ranges between 130° and 170° solar zenith angles. The ionosphere disturbance triggered by the HSSWS is also noticed by some remarkable changes of F2 layer peak height. The work is contributing to the understanding of the theoretical coupling mechanism between high speed solar winds stream and magneto-ionosphere responses and provides a reference for space weather analysis and forecasting under similar events