422 research outputs found

    Westinghouse programs in pulsed homopolar power supplies

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    This document details Westinghouse's ongoing study of homopolar machines since 1929 with the major effort occurring in the early 1970's to the present. The effort has enabled Westinghouse to develop expertise in the technology required for the design, fabrication and testing of such machines. This includes electrical design, electromagnetic analysis, current collection, mechanical design, advanced cooling, stress analysis, transient rotor performance, bearing analysis and seal technology. Westinghouse is using this capability to explore the use of homopolar machines as pulsed power supplies for future systems in both military and commercial applications

    Direct, biomimetic synthesis of (+)-artemone via a stereoselective, organocatalytic cyclization

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    We present a four-step synthesis of (+)-artemone from (–)- linalool, featuring iminium organocatalysis of a doubly diastereoselective conjugate addition reaction. The strategy follows a proposed biosynthetic pathway, rapidly generates stereochemical complexity, uses no protecting groups, and minimizes redox manipulations

    Effects of Variable Oceanographic Conditions on Forage Fish Lipid Content and Fatty Acid Composition in the Northern California Current

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    Lipids and fatty acids (FA) were investigated in 4 species of forage fish: northern anchovy Engraulis mordax, Pacific sardine Sardinops sagax, Pacific herring Clupea pallasi, and whitebait smelt Allosmerus elongatus, for their ability to serve as biological indicators of ocean conditions in the California Current large marine ecosystem (CCLME). Samples were collected during the oceanographically contrasting years of 2005 and 2006. Upwelling was severely curtailed in the spring and early summer of 2005, leading to delayed biological productivity, whereas upwelling was relatively normal in spring 2006. Principal components analysis described 78% of the variance within the lipid and FA dataset using the first 2 principal components. We found significant intra- and interspecific, interannual, and seasonal differences in lipid and FA profiles using univariate and permutation- based multivariate analysis of variance. Indicator species analysis showed distinct lipid and FA properties associated with each fish species. Using the ratio of docosahexaenoic acid (C22:6n-3) to eicosapentaeonic acid (C20:5n-3), we detected a transition from a diet composed primarily of dinoflagellate origin in early 2005 to a diet resulting from diatom-based productivity by late summer 2006. This shift was due to interannual differences in primary production, which was confirmed through phytoplankton sampling. Our study demonstrates that lipid and FA biomarkers in the forage fish community can provide information on ocean conditions and productivity that affect food web structure in the CCLME

    The band structure of BeTe - a combined experimental and theoretical study

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    Using angle-resolved synchrotron-radiation photoemission spectroscopy we have determined the dispersion of the valence bands of BeTe(100) along ΓX\Gamma X, i.e. the [100] direction. The measurements are analyzed with the aid of a first-principles calculation of the BeTe bulk band structure as well as of the photoemission peaks as given by the momentum conserving bulk transitions. Taking the calculated unoccupied bands as final states of the photoemission process, we obtain an excellent agreement between experimental and calculated spectra and a clear interpretation of almost all measured bands. In contrast, the free electron approximation for the final states fails to describe the BeTe bulk band structure along ΓX\Gamma X properly.Comment: 21 pages plus 4 figure

    Binding Energy of Charged Excitons in ZnSe-based Quantum Wells

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    Excitons and charged excitons (trions) are investigated in ZnSe-based quantum well structures with (Zn,Be,Mg)Se and (Zn,Mg)(S,Se) barriers by means of magneto-optical spectroscopy. Binding energies of negatively () and positively (X+) charged excitons are measured as functions of quantum well width, free carrier density and in external magnetic fields up to 47 T. The binding energy of shows a strong increase from 1.4 to 8.9 meV with decreasing quantum well width from 190 to 29 A. The binding energies of X+ are about 25% smaller than the binding energy in the same structures. The magnetic field behavior of and X+ binding energies differ qualitatively. With growing magnetic field strength, increases its binding energy by 35-150%, while for X+ it decreases by 25%. Zeeman spin splittings and oscillator strengths of excitons and trions are measured and discussed

    A new degree of freedom for memory allocation in clusters

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    Improvements in parallel computing hardware usually involve increments in the number of available resources for a given application such as the number of computing cores and the amount of memory. In the case of shared-memory computers, the increase in computing resources and available memory is usually constrained by the coherency protocol, whose overhead rises with system size, limiting the scalability of the final system. In this paper we propose an efficient and cost-effective way to increase the memory available for a given application by leveraging free memory in other computers in the cluster. Our proposal is based on the observation that many applications benefit from having more memory resources but do not require more computing cores, thus reducing the requirements for cache coherency and allowing a simpler implementation and better scalability. Simulation results show that, when additional mechanisms intended to hide remote memory latency are used, execution time of applications that use our proposal is similar to the time required to execute them in a computer populated with enough local memory, thus validating the feasibility of our proposal. We are currently building a prototype that implements our ideas. The first results from real executions in this prototype demonstrate not only that our proposal works but also that it can efficiently execute applications that make use of remote memory resources. © 2011 Springer Science+Business Media, LLC.This work has been supported by PROMETEO from Generalitat Valenciana (GVA) under Grant PROMETEO/2008/060.Montaner Mas, H.; Silla Jiménez, F.; Fröning, H.; Duato Marín, JF. (2012). A new degree of freedom for memory allocation in clusters. 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    Mechanism of Disruption of the Amt-GlnK Complex by PII-Mediated Sensing of 2-Oxoglutarate

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    GlnK proteins regulate the active uptake of ammonium by Amt transport proteins by inserting their regulatory T-loops into the transport channels of the Amt trimer and physically blocking substrate passage. They sense the cellular nitrogen status through 2-oxoglutarate, and the energy level of the cell by binding both ATP and ADP with different affinities. The hyperthermophilic euryarchaeon Archaeoglobus fulgidus possesses three Amt proteins, each encoded in an operon with a GlnK ortholog. One of these proteins, GlnK2 was recently found to be incapable of binding 2-OG, and in order to understand the implications of this finding we conducted a detailed structural and functional analysis of a second GlnK protein from A. fulgidus, GlnK3. Contrary to Af-GlnK2 this protein was able to bind both ATP/2-OG and ADP to yield inactive and functional states, respectively. Due to the thermostable nature of the protein we could observe the exact positioning of the notoriously flexible T-loops and explain the binding behavior of GlnK proteins to their interaction partner, the Amt proteins. A thermodynamic analysis of these binding events using microcalorimetry evaluated by microstate modeling revealed significant differences in binding cooperativity compared to other characterized PII proteins, underlining the diversity and adaptability of this class of regulatory signaling proteins

    Police officers and post traumatic stress disorder: discussing the deficit in research, identification and prevention in England and Wales

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    This article will review available literature regarding Post Traumatic Stress Disorder (PTSD) within policing in England and Wales, with a particular focus on its early identification and prevention. An overview of PTSD will be given as well as an exploration of why police officers are potentially more susceptible to this mental health condition compared to other members of society. Key factors in the early identification and prevention of PTSD will be outlined, with a focus on crisis intervention techniques which have been subject to considerable academic study. There is limited research available from England and Wales that looks specifically at PTSD in policing, this research deficit will be highlighted and key areas of research which need to be explored further will be given so that this problem can be both identified and prevented in officers

    Internet-based prevention of posttraumatic stress symptoms in injured trauma patients: design of a randomized controlled trial.

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    Background: Injured trauma victims are at risk of developing Posttraumatic Stress Disorder (PTSD) and other post-trauma psychopathology. So far, interventions using cognitive behavioral techniques (CBT) have proven most efficacious in treating early PTSD in highly symptomatic individuals. No early intervention for the prevention of PTSD for all victims has yet proven effective. In the acute psychosocial care for trauma victims, there is a clear need for easily applicable, accessible, cost-efficient early interventions. Objective: To describe the design of a randomized controlled trial (RCT) evaluating the effectiveness of a brief Internet-based early intervention that incorporates CBT techniques with the aim of reducing acute psychological distress and preventing long-term PTSD symptoms in injured trauma victims. Method: In a two armed RCT, 300 injured trauma victims from two Level-1 trauma centers in Amsterdam, the Netherlands, will be assigned to an intervention or a control group. Inclusion criteria are: being 18 years of age or older, having experienced a traumatic event according to the diagnostic criteria of the DSM-IV and understanding the Dutch language. The intervention group will be given access to the intervention's website (www.traumatips.nl), and are specifically requested to login within the first month postinjury. The primary clinical study outcome is PTSD symptom severity. Secondary outcomes include symptoms of depression and anxiety, quality of life, and social support. In addition, a cost-effectiveness analysis of the intervention will be performed. Data are collected at one week post-injury, prior to first login (baseline), and at 1, 3, 6 and 12 months. Analyses will be on an intention-to-treat basis. Discussion: The results will provide more insight into the effects of preventive interventions in general, and Internet-based early interventions specifically, on acute stress reactions and PTSD, in an injured population, during the acute phase after trauma. We will discuss possible strengths and limitations
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