Objective dysphonia quantification in vocal fold paralysis: comparing nonlinear with classical measures

Clinical acoustic voice recording analysis is usually performed using classical perturbation measures including jitter, shimmer and noise-to-harmonic ratios. However, restrictive mathematical limitations of these measures prevent analysis for severely dysphonic voices. Previous studies of alternative nonlinear random measures addressed wide varieties of vocal pathologies. Here, we analyze a single vocal pathology cohort, testing the performance of these alternative measures alongside classical measures.

We present voice analysis pre- and post-operatively in unilateral vocal fold paralysis (UVFP) patients and healthy controls, patients undergoing standard medialisation thyroplasty surgery, using jitter, shimmer and noise-to-harmonic ratio (NHR), and nonlinear recurrence period density entropy (RPDE), detrended fluctuation analysis (DFA) and correlation dimension. Systematizing the preparative editing of the recordings, we found that the novel measures were more stable and hence reliable, than the classical measures, on healthy controls.

RPDE and jitter are sensitive to improvements pre- to post-operation. Shimmer, NHR and DFA showed no significant change (p > 0.05). All measures detect statistically significant and clinically important differences between controls and patients, both treated and untreated (p < 0.001, AUC > 0.7). Pre- to post-operation, GRBAS ratings show statistically significant and clinically important improvement in overall dysphonia grade (G) (AUC = 0.946, p < 0.001).

Re-calculating AUCs from other study data, we compare these results in terms of clinical importance. We conclude that, when preparative editing is systematized, nonlinear random measures may be useful UVFP treatment effectiveness monitoring tools, and there may be applications for other forms of dysphonia.
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A Comparative Study of the Magnitude, Frequency and Distribution of Intense Rainfall in the United Kingdom

During the 1960s, a study was made of the magnitude, frequency and distribution of intense rainfall over the UK, employing data from more than 120 daily-read rain gauges covering the period 1911 to 1960. Using the same methodology, that study was recently updated utilizing data for the period 1961 to 2006 for the same gauges, or from those nearby. This paper describes the techniques applied to ensure consistency of data and statistical modelling. It presents a comparison of patterns of extreme rainfalls for the two periods and discusses the changes that have taken place. Most noticeably, increases up to 20% have occurred in the north west of the country and in parts of East Anglia. There have also been changes in other areas, including decreases of the same magnitude over central England. The implications of these changes are considered

Characterization of three types of silicon solar cells for SEPS Deep Space Mission. Volume 3: Current-voltage characteristics of spectrolab sculptured BSR/P+ (K7), BSR/P+ (K6.5) and BSR (K4.5) cells as a function of temperature and intensity

Three types of high performance silicon solar cells, sculptured BSR/P+(K7), BSR/P+(K6.5) and BSR(K4.5) manufactured by Spectrolab were evaluated for their low temperature and low intensity performance. Sixteen cells of each type were subjected to 11 temperatures and 9 intensities. The sculptured BSR/P+(K7) cells provided the greatest maximum power output both at 1 AU and at LTLI conditions. The average efficiencies of this cell were 14.4 percent at 1 SC/+25 deg C and 18.5 percent at 0.086 SC/-100 deg C

Spraying calendar

Insects and fungi cause Iowa fruit growers and gardeners a loss which in the aggregate amounts to hundreds of thousands of dollars annually. They cause fruit and vegetables to rot and to be wormy and knotty or scabby; they damage blossoms and blossom buds and so interfere more or less with the setting of the fruit; they, destroy a vast amount of foliage or injure it in such a way as to interfere with its work of building up the special kinds of food which the plant must have in order properly to sustain its life, to support its growth, to form fruit buds for the following year, and to store away in its roots, trunk, and branches the reserve supply which it needs to support its active growth during the spring until the new leaves are fully developed and ready for work. Fortunately many of the worst of these insects and diseases may be kept well under control by proper, treatment as outlined in this spraying calendar. It is not best always to follow these general recommendations exactly. The strength of the mixtures and the number of treatments should be varied to fit special cases. It must be left for the manager of the work to decide this matter, but let him remember that, as a rule, the Iowa fruit grower who would be most successful under present conditions must spray systematically and thoroughly every year

Technical management techniques for identification and control of industrial safety and pollution hazards

Constructive recommendations are suggested for pollution problems from offshore energy resources industries on outer continental shelf. Technical management techniques for pollution identification and control offer possible applications to space engineering and management

Scoping a public health impact assessment of aquaculture with particular reference to tilapia in the UK

Background. The paper explores shaping public health impact assessment tools for tilapia, a novel emergent aquaculture sector in the UK. This Research Council’s UK Rural Economy and Land Use project embraces technical, public health, and marketing perspectives scoping tools to assess possible impacts of the activity. Globally, aquaculture produced over 65 million tonnes of food in 2008 and will grow significantly requiring apposite global public health impact assessment tools.<p></p> Methods. Quantitative and qualitative methods incorporated data from a tridisciplinary literature. Holistic tools scoped tilapia farming impact assessments. Laboratory-based tilapia production generated data on impacts in UK and Thailand along with 11 UK focus groups involving 90 consumers, 30 interviews and site visits, 9 visits to UK tilapia growers and 2 in The Netherlands.<p></p> Results. The feasibility, challenges, strengths, and weaknesses of creating a tilapia Public Health Impact Assessment are analysed. Occupational and environmental health benefits and risks attached to tilapia production were identified.<p></p> Conclusions. Scoping public health impacts of tilapia production is possible at different levels and forms for producers, retailers, consumers, civil society and governmental bodies that may contribute to complex and interrelated public health assessments of aquaculture projects. Our assessment framework constitutes an innovatory perspective in the field

Gravitational Instability in Collisionless Cosmological Pancakes

The gravitational instability of cosmological pancakes composed of collisionless dark matter in an Einstein-de Sitter universe is investigated numerically to demonstrate that pancakes are unstable with respect to fragmentation and the formation of filaments. A ``pancake'' is defined here as the nonlinear outcome of the growth of a 1D, sinusoidal, plane-wave, adiabatic density perturbation. We have used high resolution, 2D, N-body simulations by the Particle-Mesh (PM) method to study the response of pancakes to perturbation by either symmetric (density) or antisymmetric (bending or rippling) modes, with corresponding wavevectors k_s and k_a transverse to the wavevector k_p of the unperturbed pancake plane-wave. We consider dark matter which is initially ``cold'' (i.e. with no random thermal velocity in the initial conditions). We also investigate the effect of a finite, random, isotropic, initial velocity dispersion (i.e. initial thermal velocity) on the fate of pancake collapse and instability. Pancakes are shown to be gravitationally unstable with respect to all perturbations of wavelength l<l_p (where l_p= 2pi/k_p). These results are in contradiction with the expectations of an approximate, thin-sheet energy argument.Comment: To appear in the Astrophysical Journal (1997), accepted for publication 10/10/96, single postscript file, 61 pages, 19 figure

Using stochastic acceleration to place experimental limits on the charge of antihydrogen

Assuming hydrogen is charge neutral, CPT invariance demands that antihydrogen also be charge neutral. Quantum anomaly cancellation also demands that antihydrogen be charge neutral. Standard techniques based on measurements of macroscopic quantities of atoms cannot be used to measure the charge of antihydrogen. In this paper, we describe how the application of randomly oscillating electric fields to a sample of trapped antihydrogen atoms, a form of stochastic acceleration, can be used to place experimental limits on this charge

Steal A Little Kiss : While Dancing

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