Lessons from the Classroom – assessing the work of postgraduate students to support better hygrothermal risk assessment

The widespread adoption of transient simulation modelling tools by building design professionals to support hygrothermal risk assessment of building design specifications is a crucial component in a multi-pronged drive to reduce moisture risk in buildings. Structured upskilling is essential. Much can be learnt about the ways practitioners use such tools by reviewing the work of professional postgraduate student groups. Such review could inform the creation of a user protocol. Peer-review under the responsibility of the organizing committee of the ICMB21

Lithium-induced Nephrotoxicity: A Case Report of Renal Cystic Disease Presenting as a Mass Lesion

AbstractLithium is an effective therapeutic agent used in the management of bipolar disorder. However, lithium is also associated with several side effects, including renal toxicity. We present a case of a symptomatic cystic mass lesion in the kidney of a patient who had a history of lithium therapy for the management of bipolar disorder

Pulsed Quantum Frequency Combs from an Actively Mode-locked Intra-cavity Generation Scheme

We introduce an intra-cavity actively mode-locked excitation scheme for nonlinear microring resonators that removes the need for external laser excitation in the generation of pulsed two-photon frequency combs. We found a heralded anti-bunching dip of 0.245 and maximum coincidence-to-accidental ratio of 110 for the generated photon pairs

On-chip Quantum State Generation by Means of Integrated Frequency Combs

Summary form only given. This paper investigates different approaches to generate optical quantum states by means of integrated optical frequency combs. These include the generation of multiplexed heralded single-photons, the first realization of cross-polarized photon-pairs on a photonic chip, the first generation of multiple two-photon entangled states, and the first realizations of multi-photon entangled quantum states on a photonic chip

Generation of Complex Quantum States Via Integrated Frequency Combs

The generation of optical quantum states on an integrated platform will enable low cost and accessible advances for quantum technologies such as secure communications and quantum computation. We demonstrate that integrated quantum frequency combs (based on high-Q microring resonators made from a CMOS-compatible, high refractive-index glass platform) can enable, among others, the generation of heralded single photons, cross-polarized photon pairs, as well as bi- and multi-photon entangled qubit states over a broad frequency comb covering the S, C, L telecommunications band, constituting an important cornerstone for future practical implementations of photonic quantum information processing

A Passively Mode-locked Nanosecond Laser with an Ultra-narrow Spectral Width

Many different mode-locking techniques have been realized in the past [1, 2], but mainly focused on increasing the spectral bandwidth to achieve ultra-short coherent light pulses with well below picosecond duration. In contrast, no mode-locked laser scheme has managed to generate Fourier-limited nanosecond long pulses, which feature narrow spectral bandwidths (~MHz regime) instrumental to applications in spectroscopy, efficient excitation of molecules, sensing, and quantum optics. The related limitations are mainly caused by the adverse operation timescales of saturable absorbers, as well as by the low strength of the nonlinear effects typically reachable through nanosecond pulses with manageable energies

2016 Student Compostition Concert

The School of Music\u27s talented student composers present a concert featuring the students\u27 original composed works performed by a wide variety of ensembles and instrumentation.https://digitalcommons.kennesaw.edu/musicprograms/1032/thumbnail.jp

Full-scale fatigue testing of a wind turbine blade in flapwise direction and examining the effect of crack propagation on the blade performance

In this paper, the sensitivity of the structural integrity of wind turbine blades to debonding of the shear web from the spar cap was investigated. In this regard, modal analysis, static and fatigue testing were performed on a 45.7 m blade for three states of the blade: (i) as received blade (ii) when a crack of 200 mm was introduced between the web and the spar cap and (iii) when the crack was extended to 1000 mm. Calibration pull-tests for all three states of the blade were performed to obtain the strain-bending moment relationship of the blade according to the estimated target bending moment (BM) which the blade is expected to experience in its service life. The resultant data was used to apply appropriate load in the fatigue tests. The blade natural frequencies in flapwise and edgewise directions over a range of frequency domain were found by modal testing for all three states of the blade. The blade first natural frequency for each state was used for the flapwise fatigue tests. These were performed in accordance with technical specification IEC TS 61400-23. The fatigue results showed that, for a 200 mm crack between the web and spar cap at 9 m from the blade root, the crack did not propagate at 50% of the target BM up to 62,110 cycles. However, when the load was increased to 70% of target BM, some damages were detected on the pressure side of the blade. When the 200 mm crack was extended to 1000 mm, the crack began to propagate when the applied load exceeded 100% of target BM and the blade experienced delaminations, adhesive joint failure, compression failure and sandwich core failure

The written declaration on epilepsy : an important achievement for Europe and beyond

On 15th September 2011, the European Written Declaration on Epilepsy was passed by the European Union (EU) Parliament. This was a significant moment for all people who have been fighting over the years for a just recognition of the importance of epilepsy in the European political agenda. The whole process described below included several months of concerted effort by Members of the European Parliament (MEPs) and by Epilepsy Advocacy Europe (EAE), a joint task force of the International League Against Epilepsy (ILAE) and the International Bureau for Epilepsy (IBE). ILAE and IBE member associations in Europe and many individuals also contributed greatly to the success of this initiative.peer-reviewe

Identification of molecular markers of delayed graft function based on the regulation of biological ageing

Introduction: Delayed graft function is a prevalent clinical problem in renal transplantation for which there is no objective system to predict occurrence in advance. It can result in a significant increase in the necessity for hospitalisation post-transplant and is a significant risk factor for other post-transplant complications. Methodology: The importance of microRNAs (miRNAs), a specific subclass of small RNA, have been clearly demonstrated to influence many pathways in health and disease. To investigate the influence of miRNAs on renal allograft performance post-transplant, the expression of a panel of miRNAs in pre-transplant renal biopsies was measured using qPCR. Expression was then related to clinical parameters and outcomes in two independent renal transplant cohorts. Results: Here we demonstrate, in two independent cohorts of pre-implantation human renal allograft biopsies, that a novel pre-transplant renal performance scoring system (GRPSS), can determine the occurrence of DGF with a high sensitivity (>90%) and specificity (>60%) for donor allografts pre-transplant, using just three senescence associated microRNAs combined with donor age and type of organ donation. Conclusion: These results demonstrate a relationship between pre-transplant microRNA expression levels, cellular biological ageing pathways and clinical outcomes for renal transplantation. They provide for a simple, rapid quantitative molecular pre-transplant assay to determine post-transplant allograft function and scope for future intervention. Furthermore, these results demonstrate the involvement of senescence pathways in ischaemic injury during the organ transplantation process and an indication of accelerated bio-ageing as a consequence of both warm and cold ischaemia