Eurasian jays do not copy the choices of conspecifics, but they do show evidence of stimulus enhancement

Corvids (birds in the crow family) are hypothesised to have a general cognitive tool-kit because they show a wide range of transferrable skills across social, physical and temporal tasks, despite differences in socioecology. However, it is unknown whether relatively asocial corvids differ from social corvids in their use of social information in the context of copying the choices of others, because only one such test has been conducted in a relatively asocial corvid. We investigated whether relatively asocial Eurasian jays ($\textit{Garrulus glandarius}$) use social information (i.e., information made available by others). Previous studies have indicated that jays attend to social context in their caching and mate provisioning behaviour; however, it is unknown whether jays copy the choices of others. We tested the jays in two different tasks varying in difficulty, where social corvid species have demonstrated social information use in both tasks. Firstly, an object-dropping task was conducted requiring objects to be dropped down a tube to release a food reward from a collapsible platform, which corvids can learn through explicit training. Only one rook and one New Caledonian crow have learned the task using social information from a demonstrator. Secondly, we tested the birds on a simple colour discrimination task, which should be easy to solve, because it has been shown that corvids can make colour discriminations. Using the same colour discrimination task in a previous study, all common ravens and carrion crows copied the demonstrator. After observing a conspecific demonstrator, none of the jays solved the object-dropping task, though all jays were subsequently able to learn to solve the task in a non-social situation through explicit training, and jays chose the demonstrated colour at chance levels. Our results suggest that social and relatively asocial corvids differ in social information use, indicating that relatively asocial species may have secondarily lost this ability due to lack of selection pressure from an asocial environment.RM and NSC received funding from the European Research Council under the European Union’s Seventh Framework Programme (FP7/2007-2013) / ERC Grant Agreement No. 3399933, awarded to NSC. CJL was funded by the Leverhulme Trust and Isaac Newton Trust with a Leverhulme Early Career Fellowship

Evolution of the one-phonon 2(1,ms)(+) mixed-symmetry state in N=80 isotones as a local measure for the proton-neutron quadrupole interaction

An inverse kinematics Coulomb excitation experiment was performed to obtain absolute E2 and M1 transition strengths in 134Xe. The measured transition strengths indicate that the 23+ state of 134Xe is the dominant fragment of the one-phonon 21, ms+ mixed-symmetry state. Comparing the energy of the 21, ms+ mixed-symmetry state in 134Xe to that of the 21, ms+ levels in the N = 80 isotonic chain indicates that the separation in energy between the fully-symmetric 21+ state and the 21, ms+ level increases as a function of the number of proton pairs outside the Z = 50 shell closure. This behavior can be understood as resulting from the mixing of the basic components of a two-fluid quantum system. A phenomenological fit based on this concept was performed. It provides the first experimental estimate of the strength of the proton-neutron quadrupole interaction derived from nuclear collective states with symmetric and antisymmetric nature

The trans-Eurasian crop exchange in prehistory: Discerning pathways from barley phylogeography

A number of crops that are of global importance today, including wheat (Triticum spp) and barley (Hordeum vulgare), were domesticated in Southwest Asia between 10,000 and 11,000 years ago and subsequently spread through the Old World, into Europe, North Africa and eastwards across Eurasia. Their routes of expansion have been a focus of debate and are increasingly being revealed by widespread dating of archaeobotanical remains from across Eurasia. Of particular interest is work by Zhao (2009) who proposed three routes for the spread of wheat into China: firstly, across the Eurasian Steppe, second by sea from India to the east coast of Eurasia and third, along the Hexi Corridor, which forms part of the Silk Road in western China. Molecular genetic analysis of cereal landraces have also elucidated routes of expansion of cereal cultivation and, in addition, have revealed how crops adapted to changing environments as they moved away from their centres of domestication. Genes involved in flowering time genes have been a particular focus of these studies, including the photoperiod response gene Ppd-H1 in barley, which controls flowering in response to increasing day-lengths in the spring. In this paper we present a phylogeographic analysis of Old World landrace and wild barley, through the analysis of a portion of the Ppd-H1 DNA sequence. We discuss the geographic distribution of different haplotypes of this gene across Eurasia in the light of Zhao (2009)'s three routes and what it potentially reveals about trans-Eurasian pathways of contact between early farming communities.This research was conducted under the auspices of the ‘Food Globalization in Prehistory’ (FOGLIP, ERC grant number 249642) and ‘Origins and Spread of Agriculture in the South West Mediterranean Region’ (AgriWestMed, ERC Grant Number 230561) research projects, both funded by the European Research Council

Thermal and electrical conductivity of iron at Earth's core conditions

The Earth acts as a gigantic heat engine driven by decay of radiogenic isotopes and slow cooling, which gives rise to plate tectonics, volcanoes, and mountain building. Another key product is the geomagnetic field, generated in the liquid iron core by a dynamo running on heat released by cooling and freezing to grow the solid inner core, and on chemical convection due to light elements expelled from the liquid on freezing. The power supplied to the geodynamo, measured by the heat-flux across the core-mantle boundary (CMB), places constraints on Earth's evolution. Estimates of CMB heat-flux depend on properties of iron mixtures under the extreme pressure and temperature conditions in the core, most critically on the thermal and electrical conductivities. These quantities remain poorly known because of inherent difficulties in experimentation and theory. Here we use density functional theory to compute these conductivities in liquid iron mixtures at core conditions from first principles- the first directly computed values that do not rely on estimates based on extrapolations. The mixtures of Fe, O, S, and Si are taken from earlier work and fit the seismologically-determined core density and inner-core boundary density jump. We find both conductivities to be 2-3 times higher than estimates in current use. The changes are so large that core thermal histories and power requirements must be reassessed. New estimates of adiabatic heat-flux give 15-16 TW at the CMB, higher than present estimates of CMB heat-flux based on mantle convection; the top of the core must be thermally stratified and any convection in the upper core driven by chemical convection against the adverse thermal buoyancy or lateral variations in CMB heat flow. Power for the geodynamo is greatly restricted and future models of mantle evolution must incorporate a high CMB heat-flux and explain recent formation of the inner core.Comment: 11 pages including supplementary information, two figures. Scheduled to appear in Nature, April 201

From ecological opportunism to multi-cropping: Mapping food globalisation in prehistory

Many of today's major food crops are distributed worldwide. While much of this ‘food globalisation’ has resulted from modern trade networks, it has its roots in prehistory. In this paper, we examine cereal crops that moved long distances across the Old World between 5000 and 1500 BC. Drawing together recent archaeological evidence, we are now able to construct a new chronology and biogeography of prehistoric food globalisation. Here we rationalize the evidence for this process within three successive episodes: pre-5000 BC, between 5000 and 2500 BC, and between 2500 and 1500 BC. Each episode can be characterized by distinct biogeographical patterns, social drivers of the crop movements, and ecological constraints upon the crop plants. By 1500 BC, this process of food globalisation had brought together previously isolated agricultural systems, to constitute a new kind of agriculture in which the bringing together of local and exotic crops enables a new form of intensification.The authors are grateful to the European Research Council, under grant 249642, “Food Globalisation in Prehistory” (FOGLIP, PI: M. K. Jones); the Leverhulme Trust, under grant f/09717/C, “Pioneers of Pan-Asian Contact”(PPAC, PI: M. K. Jones); the National Science Foundation, under grant 1826727, “The origins and spread of millet cultivation” (PI: X. Liu); the Rae and Edith Bennett Travelling Scholarship (P. J. Jones); the International Center for Energy, Environment and Sustainability (InCEES, PI: X. Liu), Washington University in St Louis; and the European Social Fund, under grant 09.3.3-LMT-K-712 “Improvement of researchers' qualification by implementing world-class R&D projects” (PI: G. Motuzaite Matuzeviciute) and Darwin College, Cambridge for financial support

Evidence for increased expression of the Amundsen Sea Low over the South Atlantic during the late Holocene

The Amundsen Sea Low (ASL) plays a major role in the climate and environment of Antarctica and the Southern Ocean, including surface air temperature and sea ice concentration changes. Unfortunately, a relative dearth of observational data across the Amundsen and Bellingshausen seas prior to the satellite era (post-1979) limits our understanding of the past behaviour and impact of the ASL. The limited proxy evidence for changes in the ASL are primarily restricted to the Antarctic where ice core evidence suggests a deepening of the atmospheric pressure system during the late Holocene. However, no data have previously been reported from the northern side of the ASL. Here we report a high-resolution, multi-proxy study of a 5000-year-long peat record from the Falkland Islands, a location sensitive to contemporary ASL dynamics which modulates northerly and westerly airflow across the southwestern South Atlantic sector of the Southern Ocean. In combination with climate reanalysis, we find a marked period of wetter, colder conditions most likely the result of enhanced southerly airflow between 5000 and 2500 years ago, suggesting limited ASL influence over the region. After 2500 years ago, drier and warmer conditions were established, implying more westerly airflow and the increased projection of the ASL onto the South Atlantic. The possible role of the equatorial Pacific via atmospheric teleconnections in driving this change is discussed. Our results are in agreement with Antarctic ice core records and fjord sediments from the southern South American coast, and suggest that the Falkland Islands provide a valuable location for reconstructing high southern latitude atmospheric circulation changes on multi-decadal to millennial timescales

Primary ovarian cancer chemotherapy: current standards of care

Chemotherapy has been regarded as standard therapy for the majority of women with advanced epithelial ovarian cancer for several decades, with this role filled largely by the alkylating agents — used as monotherapy — until the mid-1980s. The activity of cisplatin in this disorder was established during the 1970s, and combinations of cisplatin and an alkylating agent were widely used during the late 1980s. However, further research prompted by continuing concerns over poor survival and tolerability led to the adoption of paclitaxel in combination with either cisplatin or carboplatin as first-line therapy in ovarian cancer during the 1990s. Most recent research has focused on further optimisation of these regimens to maximise clinical benefit while minimising toxicity, and investigations into alternative taxanes (e.g. docetaxel), other novel agents and new treatment schedules are ongoing

Genome-Wide Mapping of DNA Methylation in Chicken

Cytosine DNA methylation is an important epigenetic modification termed as the fifth base that functions in diverse processes. Till now, the genome-wide DNA methylation maps of many organisms has been reported, such as human, Arabidopsis, rice and silkworm, but the methylation pattern of bird remains rarely studied. Here we show the genome-wide DNA methylation map of bird, using the chicken as a model organism and an immunocapturing approach followed by high-throughput sequencing. In both of the red jungle fowl and the avian broiler, DNA methylation was described separately for the liver and muscle tissue. Generally, chicken displays analogous methylation pattern with that of animals and plants. DNA methylation is enriched in the gene body regions and the repetitive sequences, and depleted in the transcription start site (TSS) and the transcription termination site (TTS). Most of the CpG islands in the chicken genome are kept in unmethylated state. Promoter methylation is negatively correlated with the gene expression level, indicating its suppressive role in regulating gene transcription. This work contributes to our understanding of epigenetics in birds

Anomalous mid-twentieth century atmospheric circulation change over the South Atlantic compared to the last 6000 years

Determining the timing and impact of anthropogenic climate change in data-sparse regions is a considerable challenge. Arguably, nowhere is this more difficult than the Antarctic Peninsula and the subantarctic South Atlantic where observational records are relatively short but where high rates of warming have been experienced since records began. Here we interrogate recently developed monthly-resolved observational datasets from the Falkland Islands and South Georgia, and extend the records back using climate-sensitive peat growth over the past 6000 years. Investigating the subantarctic climate data with ERA-Interim and Twentieth Century Reanalysis, we find that a stepped increase in precipitation across the 1940s is related to a change in synoptic atmospheric circulation: a westward migration of quasi-permanent positive pressure anomalies in the South Atlantic has brought the subantarctic islands under the increased influence of meridional airflow associated with the Amundsen Sea Low. Analysis of three comprehensively multi-dated (using 14C and 137Cs) peat sequences across the two islands demonstrates unprecedented growth rates since the mid-twentieth century relative to the last 6000 years. Comparison to observational and reconstructed sea surface temperatures suggests this change is linked to a warming tropical Pacific Ocean. Our results imply 'modern' South Atlantic atmospheric circulation has not been under this configuration for millennia