Contracts—Privity No Longer Required in Express Warranty Action

Randy Knitwear v. American Cyanamid Co., 11 N.Y.2d 5, 181 N.E.2d 399, 226 N.Y.S.2d 363 (1962)

Constitutional Law—The Serviceman’a Right to Counsel in a Special Court-Martial

Kennedy v. Commandant, 377 F.2d 339 (10th Cir. 1967)

Contracts—Purchase Option Clause Noncontinuance In Lease Extension Agreements

Gulf Oil Corp. v. Buram Realty Co., 11 N.Y.2d 223, 182 N.E.2d 608, 228 N.Y.S.2d 225 (1962)

Evidence—Admission Into Evidence Of Company’s Operating Rule Proper On Question of Negligence

Danbois v. New York Cent. R.R., 12 N.Y.2d 234, 189 N.E.2d 468, 238 N.Y.S.2d 921 (1963)

N-Acylethanolamines in human reproductive fluids

N-Acylethanolamines (NAEs) are an important family of lipid-signaling molecules. Arachidonylethanolamide (anandamide) (AEA), palmitoylethanolamide (PEA), and oleoylethanolamide (OEA) are co-produced from similar phospholipid precursors when neurons are stimulated. AEA is an endogenous agonist (endocannabinoid) for cannabinoid receptors. It binds with higher affinity to type CB1 than to type CB2 cannabinoid receptors. PEA does not bind to CB1, while the hypothesis that it reacts with putative CB2-like receptors has been questioned. OEA does not activate currently known cannabinoid receptors, but it mimics the effects of AEA and cannabinoids in reducing the fertilizing capacity of sea urchin sperm. OEA and PEA also act as entourage compounds by inhibiting the hydrolysis of AEA by fatty acid amide hydrolase. Cannabinoid receptors and/or AEA are present in mammalian reproductive organs including the testis, epididymis, prostate, ovary, uterus, sperm, preimplantation embryo and placenta, as well as prostatic and mammary carcinomas. We now report that analysis by high-performance liquid chromatography/mass spectrometry (HPLC/MS) shows the presence of AEA, PEA, and OEA in human seminal plasma, mid-cycle oviductal fluid, follicular fluid, amniotic fluid, milk, and fluids from malignant ovarian cysts. Previous studies showed that AEA-signaling via cannabinoid receptors regulates capacitation and fertilizing potential of human sperm, early embryonic development and blastocyst implantation into the uterine mucosa of rodents, as well as proliferation of human mammary and prostatic carcinomas. Current results imply that NAEs also may modulate follicular maturation and ovulation, normal and pathological ovarian function, placental and fetal physiology, lactation, infant physiology, and behavior. Collectively, these findings suggest that NAEs in human reproductive fluids may help regulate multiple physiological and pathological processes in the reproductive system, and imply that exogenous cannabinoids delivered by marijuana smoke might impact these processes. This study has potential medical and public policy ramifications because of the incidence of marijuana abuse by adolescents and adults in our society, previously documented reproductive effects of marijuana, and the ongoing debate about medicinal use of marijuana and cannabinoids

Constitutional Law—The Serviceman’a Right to Counsel in a Special Court-Martial

Kennedy v. Commandant, 377 F.2d 339 (10th Cir. 1967)

Personal And Real Property—Use of Lis Pendens in an Action to Enjoin a Nuisance

Anchorage Woods, Inc., 10 N.Y.2d 302, 178 N.E.2d 717, 222 N.Y.S.2d 316 (1961)

Distributed rail traffic management under moving-block signalling

With the ambition of policy makers to encourage a modal shift to rail, an increase in the demand for running trains can be expected. Capacity wise, this increase in demand could be facilitated by applying moving-block signalling. If railway traffic increases however, so does the difficulty of managing it. Rescheduling systems are currently being developed to help traffic managers with this task. An increase in traffic does however increase the computation time needed for solving the conflict resolution optimization problem tackled by these systems. This could pose a problem since traffic management is a task performed in real-time. An often proposed technique to reduce computation time for conflict resolution is decomposing the problem into multiple coordinated sub-problems. Until now, no research has been performed combining moving-block signalling with decomposition of the conflict resolution problem. This research addresses this gap by developing and testing a distributed moving-block conflict resolution model. The effect of the model on computation time and solution quality in comparison to a centralized model is investigated through a case study of the rail network of the Dutch province Noord-Brabant. The results show a clear improvement in computation time for the distributed model while the solution quality improves or remains the same in the majority of tested scenarios.Civil Engineering | Transport and Plannin

Evidence—Admission Into Evidence Of Company’s Operating Rule Proper On Question of Negligence

Danbois v. New York Cent. R.R., 12 N.Y.2d 234, 189 N.E.2d 468, 238 N.Y.S.2d 921 (1963)