73 research outputs found
Face Recognition with Facial Occlusion Based on Local Cycle Graph Structure Operator
Facial occlusion is a difficulty in the field of face recognition. The lack of features caused by occlusion may reduce the face recognition rate greatly. How to extract the identified features from the occluded faces has a profound effect on face recognition. This chapter presents a Local Cycle Graph Structure (LCGS) operator, which makes full use of the information of the pixels around the target pixel with its neighborhood of 3 × 3. Thus, the recognition with the extracted features is more efficient. We apply the extreme learning machine (ELM) classifier to train and test the features extracted by LCGS algorithm. In the experiment, we use the olivetti research laboratory (ORL) database to simulate occlusion randomly and use the AR database for physical occlusion. Physical coverings include scarves and sunglasses. Experimental results demonstrate that our algorithm yields a state-of-the-art performance
Baicalin ameliorates insulin resistance and regulates hepatic glucose metabolism via activating insulin signaling pathway in obese pre-diabetic mice
Background: Diabetes belongs to the most prevalent metabolic diseases worldwide, which is featured with insulin resistance, closely associated with obesity and urgently needs to be treated. Baicalin, belonging to natural flavonoids, has been reported to inhibit oxidative stress or inflammatoin.
Purpose: This study investigated the properties of baicalin on modulating abnormal glucolipid metabolism, as well as the underlying in-vitro and in-vivo mechanisms.
Methods: Insulin-resistant (IR)-HepG2 cells were stimulated by dexamethasone (20 µM) and high glucose (50 mM) for 48 h and incubated with or without baicalin or metformin for another 16 h. Male C57BL/6 J mice were fed with a high-fat diet (HFD, 60 % kcal% fat) during the total 14 weeks. Obese mice were then administered with baicalin (50 and 100 mg/kg) or vehicle solution everyday through oral gavage during the last 4-week period. Moreover, baicalin metabolisms in vitro and in vivo were determined using UPLC/MS/MS to study its
metabolism situation.
Results: Exposure to dexamethasone and high glucose damaged the abilities of glycogen synthesis and glucose uptake with elevated oxidative stress and increased generation levels of advanced glycation end-products (AGEs) in HepG2 cells. These impairments were basically reversed by baicalin treatment. Four-week oral administration with baicalin ameliorated hyperglycemia and dyslipidemia in HFD-induced obese and pre-diabetic mice. Downregulation of IRS/PI3K/Akt signaling pathway accomplished with reduced GLUT4 expression and enhanced GSK-3β activity was observed in insulin resistant HepG2 cells as well as liver tissues from pre-diabetic mice; and such effect was prevented by baicalin. Moreover, baicalin and its matabolites were detected in IRHepG2 cells and mouse plasma.
Conclusion: The study illustrated that baicalin alleviated insulin resistance by activating insulin signaling pathways and inhibiting oxidative stress and AGEs production, revealing the potential of baicalin to be a therapeutic natural flavonoid against hepatic insulin and glucose-lipid metabolic disturbance in pre-diabetes accompanied with obesity.Agencia Estatal de Investigación | Ref. RYC2020–030365-IXunta de Galicia | Ref. ED431F2022/01Universidade de Vigo/CISU
Mineralogical characterization of manganese oxide minerals of the Devonian Xialei manganese deposit
The Guangxi Zhuang Autonomous Region is an important manganese ore district in Southwest China, with manganese ore resource reserves accounting for 23% of the total manganese ore resource reserves in China. The Xialei manganese deposit (Daxin County, Guangxi) is the first super-large manganese deposit discovered in China. The Mn oxide in the supergene oxidation zone of the Xialei deposit was characterized using scanning electron microscopy (SEM), energy spectrometer (EDS), transmission electron microscopy (TEM, HRTEM), and X-ray diffraction analysis (XRD). The Mn oxides have a gray-black/steel-gray color, a semi-metallic-earthy luster, and appear as oolitic, pisolitic, banded, massive, and cellular textures. Scanning electron microscopy images show that the manganese oxide minerals are present as fine-spherical particles with an earthy surface. TEM and HRTEM indicate the presence of oriented bundled and staggered nanorods, and nanopores between the crystals. The Mn oxide ore can be classified into two textural types: (1) oolitic and pisolitic (often with annuli) Mn oxide, and (2) massive Mn oxide. Pyrolusite, cryptomelane, and hollandite are the main Mn oxide minerals. The potassium contents of cryptomelane and pyrolusite are discussed. The unit cell parameters of pyrolusite are refined
Screening and identification of the dominant antigens of the African swine fever virus
African swine fever is a highly lethal contagious disease of pigs for which there is no vaccine. Its causative agent African swine fever virus (ASFV) is a highly complex enveloped DNA virus encoding more than 150 open reading frames. The antigenicity of ASFV is still unclear at present. In this study, 35 proteins of ASFV were expressed by Escherichia coli, and ELISA was developed for the detection of antibodies against these proteins. p30, p54, and p22 were presented as the major antigens of ASFV, positively reacting with all five clinical ASFV-positive pig sera, and 10 pig sera experimentally infected by ASFV. Five proteins (pB475L, pC129R, pE199L, pE184L, and pK145R) reacted well with ASFV-positive sera. The p30 induced a rapid and strong antibody immune response during ASFV infection. These results will promote the development of subunit vaccines and serum diagnostic methods against ASFV
Influence of paste thickness on the coated aggregates on properties of high-density sulphoaluminate cement concrete
An improved method for the densified mixture design algorithm and Fuller curve were used to design high-density sulphoaluminate cement concrete (HDSC). The performance of HDSC is significantly influenced by the paste thickness on the coated aggregates. Sulphoaluminate cement concrete mixtures containing aggregates coated with 3 different paste thickness of t=10μm, 20μm, and 30μm and water-binder ratios (W/B) of 0.25, 0.30 and 0.35 were prepared. The results of experiments show that paste thickness on the coated aggregates significantly influences the mechanical properties and durability of HDSC. With the increase of paste thickness, the compressive strength is increased, but the electrical resistivity is decreased, particularly at the early ages of 1 and 3 days. The sulfate corrosion resistance coefficients of HDSC are larger than 1.0, the total porosity can be less than 7%, and the micropore (i.e. with pore size less than 20nm) can be larger than 70%
Stimulated Raman scattering microscopy for rapid brain tumor histology
Rapid histology of brain tissues with sufficient diagnostic information has the great potential to aid neurosurgeons during operations. Stimulated Raman Scattering (SRS) microscopy is an emerging label-free imaging technique, with the intrinsic chemical resolutions to delineate brain tumors from normal tissues without the need of time-consuming tissue processing. Growing number of studies have shown SRS as a “virtual histology” tool for rapid diagnosis of various types of brain tumors. In this review, we focus on the basic principles and current developments of SRS microscopy, as well as its applications for brain tumor imaging
A new risk probability calculation method for urban ecological risk assessment
The ecological risk associated with urbanization is of great concern where multiple stressors and risk receptors co-exist. Probabilistic risk characterization methods were rarely applied in past urban ecological risk assessments because of the difficulties in the derivation of theoretical probability distribution functions and the definite integral calculation. Therefore, we proposed a new method which is based on computer simulation and able to facilitate the calculation of risk probabilities. This method quantifies multiple ecological risk-related indicators using ecological models, implements Monte Carlo simulation to calculate the risk probability of single indicators, and applies the copula model to calculate the joint risk probability of multiple indicators. We conducted an assessment of urban ecological risk related to urban surface water environment in Beijing as a case study to validate this method. The results show that the means of surface runoff risk probability, total nitrogen pollutant load risk probability, and comprehensive (joint) risk probability were 0.33, 0.44, and 0.23, respectively, in the areas within Beijing Sixth Ring Road. All three types of risk were at moderate levels in the study areas, but exhibited high spatial heterogeneity and urban–suburban gradient. The average contributions of the three risk types were 25% (surface runoff risk), 32% (total nitrogen pollutant load risk), and 43% (comprehensive risk), indicating that the joint risk was overall the major risk type. In conclusion, our method considering multiple indicators and their probabilistic attributes can handle the uncertainties in ecological models and thus has potential to evaluate different types of urban ecological risks
A Review on Ultrafast-Laser Power Bed Fusion Technology
Additive manufacturing of metals by employing continuous wave and short pulse lasers completely changes the way of modern industrial production. But the ultrafast laser has the superiority to short pulse laser and continuous wave laser in additive manufacturing. It has higher peak power, small thermal effect, high machining accuracy and low damage threshold. It can effectively perform additive manufacturing for special materials and improve the mechanical properties of parts. This article reviews the mechanism of the interaction between ultrafast laser and metal materials to rule the manufacturing processes. The current application of ultrafast laser on forming and manufacturing special materials, including refractory metals, transparent materials, composite materials and high thermal conductivity materials are also discussed. Among the review, the shortcomings and challenges of the current experimental methods are discussed as well. Finally, suggestions are provided for the industrial application of ultrashort pulse laser in the field of additive manufacturing in the future
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