Attitudes and Emotions to Internet Safety: Trust and Digital Literacy in Mothers of Reception Aged Children

Although there is a vast amount of literature available on child internet safety, most of this concentrates on older children over the age of eight (Holloway, Green & Livingstone, 2013). Research that has focused on younger (under seven) children often omits to include the parents’ perspectives, which are pivotal to child internet safety management within the home (Livingstone, Haddon, Gorzig & Olfasson, 2011). This study focuses on this gap by exploring the views of parents of children under seven in relation to internet safety management. It provides insight into factors that affect how parents manage access to digital technologies within the home. In particular, the factors considered are, parents’ attitudes and emotions to the internet, their level of digital literacy, and how trust affects parents’ attitudes and emotions towards child internet safety. The research is based on a small scale study of parents’ experiences and perceptions. Data was collected from six parents of younger children using in depth semi structured interviews and analysed using Interpretative Phenomenological Analysis. The study argues that the notion of trust is central to understanding younger children’s internet safety. Parental levels of trust in digital systems were found to play an important role in how child internet safety was managed within the home. Bronfenbrenner’s (1977) Ecological Systems Theory was used to interpret the complex relationships that surround family digital activities. The findings suggest that parental levels of digital literacy were significant in forming parents’ opinions and decisions, about how they managed internet safety. In addition, findings revealed trust was subjective and complex and often elicited a need for parents to feel in control. This study proposes a model to understand how trust, digital literacy and child internet safety strategies used by parents might be understood, which has been called the Digital Trust Window

Collaborating across Organizations for a Remote Area Medical Event: Providing Consumer Health Information and Assessing Health Literacy

Objective: The University of Tennessee’s Preston Medical Library’s (PML) consumer health information service partnered with local librarians and Remote Area Medical (RAM) to increase consumer health information access as well as assess health literacy levels of RAM attendees. Methods: Librarians contacted RAM and obtained permission to both participate in the Knoxville, TN event and conduct anonymous health literacy assessments using the Newest Vital Sign (NVS) tool. Approval was obtained from PML’s institutional IRB. An email gauging participation interest was sent to local librarians at various institutions. A Zoom meeting was then set up to discuss RAM and participant expectations. A librarian with previous experience of partnering with RAM spoke at the meeting about his experiences and answered questions. Librarians volunteered for specific times so that two people were always at the library’s information table. Results: Ten librarians from across four different academic institutions attended the February RAM event and staffed a table with consumer health information handouts, health information request forms, and other informational materials. 137 people visited the table and 13 filled out health information request forms. Mental health was the subject area most frequently requested. Sixteen participants completed the NVS health literacy assessment tool. Results indicate that the majority of participants likely had adequate health literacy. Conclusions: Participating in the RAM event allowed for collaboration with multiple institutions in the local area, further building relationships for future collaborative efforts. Through participating in the Knoxville RAM event and analyzing collected data, researchers sampled health literacy of RAM attendees and planned more focused consumer health information outreach. Two other RAM events in east Tennessee were cancelled due to the COVID-19 pandemic; the library will participate in the annual Knoxville RAM event on a continual basis

Strategies for Systems Change: Lessons Learned from the Transforming Early Educator Lead Teacher Preparation Programs Through Multi-Partner Innovation Grant Program

In 2021–22, The Collaborative awarded eight grants in support of partnerships between institutions of higher education (IHEs) and states/territories/tribal nations to transform their preparation programs for early educators. To support our grantees in their work, The Collaborative engaged School Readiness Consulting (SRC) to develop a learning community to foster peer learning and collective problem-solving.Two years into this work, The Collaborative and SRC provided grantees with an opportunity to reflect on their experiences through the lens of an overarching question: How have the IHEs and their partners made meaningful, systemic changes to address barriers on their campuses, in their communities, and in the field at large?This report describes the strategies grantees used for systems change, as well as their reflections on next steps and sustainability.Key insights from the report include:Grantees readily leveraged policies, practices, and resources to create immediate and measurable impacts on their institutions and their students. Strategies include centering equity in student recruitment and retention, enhancing coursework offerings and strengthening classes related to culturally relevant practices, and investing in resources driven by the actual needs of their students.In addition, grantees identified strategies to create the conditions needed to maintain progress and enable further changes to best support their students. These strategies include strengthening and creating connections, shifting power dynamics, and changing mental models

Severely Photosensitive Psoriasis: A Phenotypically Defined Patient Subset

A subset of patients with chronic plaque psoriasis exhibits severely photosensitive psoriasis (PP) with a pronounced seasonal pattern, but the pathomechanism is not understood. We performed two related studies; first, a detailed clinical characterization of PP, and second, a controlled investigation exploring the underlying pathomechanisms through the assessment of disease onset after photoprovocation. Patients with PP (n=20) showed striking female predominance (19F:1M), very low mean age of psoriasis onset (11 years, range 2–24), family history of psoriasis (13/20), a strong HLA–Cw*0602 association (16/17), and a rapid abnormal clinical response to broadband UVA, comprising erythema±scaling plaques (17/20). Subsequently, patients with PP (n=10), non-PP (n=9), and healthy volunteers (n=11) were challenged with low-dose broadband UVA on 3 consecutive days, and serial biopsies were taken after 6hours to 7 days and from unchallenged skin. Histological changes consistent with early psoriasis occurred in 4 of 10 PP patients, but in neither of the control groups, with significant dermal infiltration by neutrophils, CD4+, CD8+, and CD45RO+ cells at 24h, accompanied by acanthosis. Thus, a phenotypically distinct subset of psoriasis has been characterized. In contrast with earlier assumptions, UV can provoke psoriasiform features rapidly de novo; a role for memory effector T cells is supported in the early phase

Core data set on safety, efficacy, and durability of hemophilia gene therapy for a global registry: Communication from the SSC of the ISTH

BackgroundGene therapy for people with hemophilia (PWH) will soon become available outside current clinical trials. The World Federation of Hemophilia (WFH), in collaboration with International Society of Thrombosis and Hemostasis Scientific and Standardization Committee (ISTH SSC), the European Haemophilia Consortium (EHC), the US National Hemophilia Foundation (NHF), the American Thrombosis and Hemostasis Network (ATHN), industry gene therapy development partners and Regulatory liaisons have developed the Gene Therapy Registry (GTR), designed to collect long- term data on all PWH who receive hemophilia gene therapy.ObjectiveThe objectives of the GTR are to record the long- term safety and efficacy data post gene therapy infusion and to assess the changes in quality of life and burden of disease post- gene- therapy infusion.MethodsThe GTR is a prospective, observational, and longitudinal registry developed under the guidance of a multi- stakeholder GTR Steering Committee (GTR SC), composed of health care professionals, patient advocates, industry representatives, and regulatory agency liaisons. All PWH who receive gene therapy by clinical trial or commercial product will be invited to enrol in the registry through their hemophilia treatment centers (HTCs). The registry aims to recruit 100% of eligible post gene therapy PWH globally. Through an iterative process, and following the guidance of the European Medicines Agency (EMA) and the US Food and Drug Administration (FDA), the GTR SC has developed a core set of data to be collected on all patients post gene therapy.ResultsThe core data set includes demographic information, vector infusion details, safety, efficacy, quality of life and burden of disease.ConclusionsThe GTR is a global effort to ensure that long term safety and efficacy outcomes are recorded and analysed and rare adverse events, in a small patient population, are identified. Many unknowns on the long- term safety and efficacy of gene therapy for hemophilia may also be addressed.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/163440/2/jth15023.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/163440/1/jth15023_am.pd

Seasonally stable temperature gradients through supraglacial debris in the Everest region of Nepal, Central Himalaya

Rock debris covers about 30% of glacier ablation areas in the Central Himalaya and modifies the impact of atmospheric conditions on mass balance. The thermal properties of supraglacial debris are diurnally variable but remain poorly constrained for monsoon-influenced glaciers over the timescale of the ablation season. We measured vertical debris profile temperatures at 12 sites on four glaciers in the Everest region with debris thickness ranging from 0.08–2.8 m. Typically, the length of the ice ablation season beneath supraglacial debris was 160 days (15 May to 22 October)—a month longer than the monsoon season. Debris temperature gradients were approximately linear (r2 > 0.83), measured as –40°C m–1 where debris was up to 0.1 m thick, –20°C m–1 for debris 0.1–0.5 m thick, and –4°C m–1 for debris greater than 0.5 m thick. Our results demonstrate that the influence of supraglacial debris on the temperature of the underlying ice surface, and therefore melt, is stable at a seasonal timescale and can be estimated from near-surface temperature. These results have the potential to greatly improve the representation of ablation in calculations of debris-covered glacier mass balance and projections of their response to climate change.Peer reviewe

Seasonally stable temperature gradients through supraglacial debris in the Everest region of Nepal, Central Himalaya

Rock debris covers about 30% of glacier ablation areas in the Central Himalaya and modifies the impact of atmospheric conditions on mass balance. The thermal properties of supraglacial debris are diurnally variable but remain poorly constrained for monsoon-influenced glaciers over the timescale of the ablation season. We measured vertical debris profile temperatures at 12 sites on four glaciers in the Everest region with debris thickness ranging from 0.08–2.8 m. Typically, the length of the ice ablation season beneath supraglacial debris was 160 days (15 May to 22 October)—a month longer than the monsoon season. Debris temperature gradients were approximately linear (r2 > 0.83), measured as –40°C m–1 where debris was up to 0.1 m thick, –20°C m–1 for debris 0.1–0.5 m thick, and –4°C m–1 for debris greater than 0.5 m thick. Our results demonstrate that the influence of supraglacial debris on the temperature of the underlying ice surface, and therefore melt, is stable at a seasonal timescale and can be estimated from near-surface temperature. These results have the potential to greatly improve the representation of ablation in calculations of debris-covered glacier mass balance and projections of their response to climate change.Peer reviewe

Midwives Understanding of Physical Activity Guidelines During Pregnancy

Objective to examine the current level of understanding held by midwives regarding the NICE physical activity guidelines in the UK, and to investigate the physical activity guidance given to women during pregnancy. Design an 11 question online survey comprising of a mixture of closed and open ended questions. Setting data reflects participants sampled across the United Kingdom. Participants fifty-nine midwives completed the online survey Measurements and findings an electronic survey was used to explore the midwives understanding of physical activity guidelines during pregnancy, and the advice they offered to women in their care. Qualitative content analysis was used to gain a more in-depth understanding of midwife knowledge. Two per cent of midwives correctly identified the physical activity guidelines, with 44 giving partially correct responses, 25 giving incorrect responses and 29 unsure of what the guidelines are. Despite the low level of correct responses, 59 of respondents reported they were confident or very confident in answering questions regarding physical activity. Only 4 of respondents reported having access to continual professional development (CPD) in the area of PA guidance. Key conclusions there appears to be a misplaced confidence amongst midwives in their knowledge of the NICE PA guidelines for pregnancy. Implications for practice as physical inactivity can be detrimental for the health of both mother and baby, there is a clear need for better dissemination of the current and future NICE physical activity guidelines in primary health care settings. The current study determined a substantial lack of CPD in the area of PA guidance, which may be a contributing factor to the lack of knowledge of the guidelines. As such, increasing CPD may in turn improve the accuracy of the advice given to pregnant women and consequently benefit the health of both mother and baby. © 2018 Elsevier Lt

Early recognition of coeliac disease through community pharmacies: A proof of concept study

Setting: 15 community pharmacies in the UK Objective: Proof of concept study to test the use of community pharmacies for active case finding of patients with coeliac disease. Method: Customers accessing over-the counter and prescription medicines indicated in the treatment of possible symptoms of coeliac disease over a six month period were offered a free point of care test. All patients were given advice regarding the test results and those who tested positive were advised to make an appointment with their general practitioner. Patients and pharmacists involved in service provision were asked to complete a satisfaction survey. Pharmacists were additionally invited to undertake interviews to better understand their views on the service. Main outcome measures: Feasibility of service, acceptability to stakeholders and proportion testing positive for coeliac disease. Results: Of the 551 individuals tested, 52 (9.4%) tested positive. 277 (50.3%) were tested for accessing irritable bowel syndrome treatment, 142 (25.8%) due to presenting for diarrhoea. The proportion of patients testing positive with different symptoms or for different treatments were similar. Of 43 customers who returned the satisfaction survey, all would recommend the service to others, believing the community pharmacy to be a suitable location. Community pharmacists believed that it enabled them to improve relationships with their customers and that medical practices were receptive to the service. Conclusion: This proof of concept study has shown that community pharmacies using a point of care test can effectively recognise and refer patients for confirmatory coeliac disease testing with high levels of customer and service provider satisfaction