A review of the use of terrestrial laser scanning application for change detection and deformation monitoring of structures

Change detection and deformation monitoring is an active area of research within the field of engineering surveying as well as overlapping areas such as structural and civil engineering. The application of Terrestrial Laser Scanning (TLS) techniques for change detection and deformation monitoring of concrete structures has increased over the years as illustrated in the past studies. This paper presents a review of literature on TLS application in the monitoring of structures and discusses registration and georeferencing of TLS point cloud data as a critical issue in the process chain of accurate deformation analysis. Past TLS research work has shown some trends in addressing issues such as accurate registration and georeferencing of the scans and the need of a stable reference frame, TLS error modelling and reduction, point cloud processing techniques for deformation analysis, scanner calibration issues and assessing the potential of TLS in detecting sub-centimetre and millimetre deformations. However, several issues are still open to investigation as far as TLS is concerned in change detection and deformation monitoring studies such as rigorous and efficient workflow methodology of point cloud processing for change detection and deformation analysis, incorporation of measurement geometry in deformation measurements of high-rise structures, design of data acquisition and quality assessment for precise measurements and modelling the environmental effects on the performance of laser scanning. Even though some studies have attempted to address these issues, some gaps exist as information is still limited. Some methods reviewed in the case studies have been applied in landslide monitoring and they seem promising to be applied in engineering surveying to monitor structures. Hence the proposal of a three-stage process model for deformation analysis is presented. Furthermore, with technological advancements new TLS instruments with better accuracy are being developed necessitating more research for precise measurements in the monitoring of structures

Expression of the immune modulator secretory leukocyte protease inhibitor (SLPI) in colorectal cancer liver metastases and matched primary tumors is associated with a poorer prognosis

Secretory leukocyte protease inhibitor (SLPI), a pleiotropic protein expressed by healthy intestinal epithelial cells, functions as an inhibitor of NF-κB and neutrophil proteases and exerts antimicrobial activity. We previously showed SLPI suppresses intestinal epithelial chemokine production in response to microbial contact. Increased SLPI expression was recently detected in various types of carcinoma. In addition, accumulating evidence indicates SLPI expression is favorable for tumor cells. In view of these findings and the abundance of SLPI in the colonic epithelium, we hypothesized SLPI promotes colorectal cancer (CRC) growth and metastasis. Here, we aimed to establish wh

Recognising Victimhood: Lessons from the International Criminal Court and Mass Claim Programmes for the Compensation Procedure Parallel to the Trial of International Crimes in the Netherlands

In the Netherlands, the Dutch criminal court in The Hague (hereinafter: ‘Netherlands International Crimes Court’ or ‘NIC court’) is assigned to try international crimes, and to provide compensation to victims of such crimes. Whereas it has specific criminal laws at its disposal to try international crimes, it applies ‘regular’ Dutch civil law to assess claims for compensation. Yet compensation for international crimes entails challenges that are quite different from domestic crimes: international crimes are normally committed against a large number of victims, and frequently result in bodily harm. This article argues that the NIC court will most likely rule a large number of claims for compensation inadmissible, as a consequence of which victims cannot benefit from the advantages inherent in the award of compensation within the criminal process. It then explores the adjudicative and reparatory standards that the International Criminal Court and mass claim programmes have applied to simplify both the adjudication of a large number of claims, and the calculation of a large number of instances of bodily damage. It is submitted that adoption by the NIC court of international reparatory standards could facilitate the assessment of a large number of civil claims within the criminal process, without prejudice to the legitimate interests of the defendant for an adequate procedure. However, these standards require the NIC court to strike a new balance between tailor-made compensation and symbolic compensation, and thereby between corrective justice and restorative justice

ESA ice sheet CCI: derivation of the optimal method for surface elevation change detection of the Greenland ice sheet - round robin results

For more than two decades, radar altimetry missions have provided continuous elevation estimates of the Greenland ice sheet (GrIS). Here, we propose a method for using such data to estimate ice-sheet-wide surface elevation changes (SECs). The final data set will be based on observations acquired from the European Space Agency’s Environmental Satellite (ENVISAT), European Remote Sensing (ERS)-1 and -2, CryoSat-2, and, in the longer term, Sentinel-3 satellites. In order to find the best-performing method, an intercomparison exercise has been carried out in which the scientific community was asked to provide their best SEC estimates as well as feedback sheets describing the applied method. Due to the hitherto few radar-based SEC analyses as well as the higher accuracy of laser data, the participants were asked to use either ENVISAT radar or ICESat (Ice, Cloud, and land Elevation Satellite) laser altimetry over the Jakobshavn Isbræ drainage basin. The submissions were validated against airborne laser-scanner data, and intercomparisons were carried out to analyse the potential of the applied methods and to find whether the two altimeters were capable of resolving the same signal. The analyses found great potential of the applied repeat-track and cross-over techniques, and, for the first time over Greenland, that repeat-track analyses from radar altimetry agreed well with laser data. Since topography-related errors can be neglected in cross-over analyses, it is expected that the most accurate, ice-sheet-wide SEC estimates are obtained by combining the cross-over and repeat-track techniques. It is thus possible to exploit the high accuracy of the former and the large spatial data coverage of the latter. Based on CryoSat’s different operation modes, and the increased spatial and temporal data coverage, this shows good potential for a future inclusion of CryoSat-2 and Sentinel-3 data to continuously obtain accurate SEC estimates both in the interior and margin ice sheet

Mrp1 is involved in lipid presentation and iNKT cell activation by Streptococcus pneumoniae

The CD1d pathway present lipid antigens resulting in the activation of iNKT cells but the complete pathway remains to be fully elucidated. Here, Chandra et al. use an siRNA screen and identify Mrp1 as crucial for CD1d lipid presentation and activation of iNKT in the context of Streptococcus pneumoniae infection

Sea Lake Charrette, dancing under the stars

Abstract not available