541 research outputs found
The protection of property rights through compensation -- observations from Taiwan
Literature suggests three compensation principles for property expropriation full, lump sum and market value. While it is difficult to judge which principle is superior, there is no doubt that everyone should be treated equally. Owners of property in Taiwan are required through valuation practices rather than by legislation to give up part of their property value in the public interest. Compensation to the expropriated property owners is collectively paid by the citizens, usually through taxation, and all property owners are equally liable to lose property. The tradeoff between tax burden and excessive sacrifice finds a balance at market value.
Taiwan applies the same valuation methodology to both property taxation assessment and expropriation compensation. The taxbased value has proved to be significantly below the market value. However, the gap between the assessed and market value is narrowed by a deliberate increase in the announced current land value shortly before expropriation.
This article presents a comparison of market value and compensation amount for a set of sample properties in Taiwan on the assumption that they were to be expropriated. Its main finding is that the gap between the two is not uniform among properties. That is to say, under the present ad hoc valuation rule, some properties tend to be overcompensated while some others are undercompensated relative to market value. The empirical analysis has uncovered two valuation issues related to compensation in Taiwan that warrant further investigation: (i) whether the ad hoc valuation rules plus the flexible additional compensation satisfactorily reflect the market value; and (ii) whether the difference between market value and the amount of compensation determined remains uniform among properties
Further Empirical Examination of an Improved Sales Comparison Approach
Despite the significant advances in applying regression analysis
into property valuation, the main features of the sales comparison approach lack thorough research. A series of works have endeavoured to retain the essence of the sales comparison approach, while at the same time take advantage of regressions to derive not only the implicit values of property attributes, but also the degree of similarity between properties. Despite these improvements, the determination of the best regression forms and the piecemeal-type of price adjustment remain vexing problems. The nearest neighbours method assumes that the effects of all attribute differences between the subject and comparable properties are captured by the Mahalanobis distance. The indicated market value of the subject property is simply a weighted average of the actual selling prices of the comparable properties. This method sidesteps the above vexing difficulties and seems worth employing. The present study extends the application of the nearest neighbours method to high-density residential properties, which have not previously been examined. In terms of both the average and coefficient of variations for prediction errors, neither the conventional regression nor the nearest neighbours method outperforms the other. Nevertheless, the distribution of the accumulated prediction errors suggests that the nearest neighbours method is superior over the regression analysis approach. Our empirical findings are, therefore, in favour of further pursuit along the small sample (comparables) methods
The Magnitude of Switching Costs for Corporate Antivirus Software Switching Decision
Today’s businesses environment is forcing companies to become increasingly more efficient in applying Internet technology to conduct transactions. AS the possibility of infection by computer virus is much greater now than ever before, businesses search for appropriate corporate antivirus software to safeguard their computer systems. This paper considers corporate antivirus software switching as one of the major security selection problem and proposes possible avenues for software switching decision and management.
In conceptual model, we draw upon switching costs where transaction costs, learning costs, and artificial costs were examined as main costs for software switching decision. Our findings shown only two out of three types of switching costs have influence over corporate antivirus software switching decisions. Despite the existence of switching costs, businesses continue to repeat software switching because the perceived risks of security threats are much greater than the switching cost itself. Furthermore, we examine various approaches to the cost of switching and then propose an index map to evaluate switching decision. Five sets of propositions are advanced to help guide this research
Case Study of Altruistic Behavior and Relational Network with Business Value on Local Travel Agency
The present study based on a local travel agency in Tainan, investigation how does the altruistic behavior affected the relational network and created the business value. The case company’s CEO had voluntary participated in charity societies more than 20 years. The present study first showed how the case company’s CEO to build an emotional relational network through altruistic behavior. Second, how does the emotional relational network form mixed relational network based on the key features demonstrated by altruistic behavior. Finally, also showed how the mixed relational network is transfer into an instrumental relational network. The results showed that the altruistic behavior can help local travel agency develop and increase their business value via relational network. The key factors to maximize the business value are the professional knowledge and altruistic behavior
Synergistic effect of imp/ostA and msbA in hydrophobic drug resistance of Helicobacter pylori
<p>Abstract</p> <p>Background</p> <p>Contamination of endoscopy equipment by <it>Helicobacter pylori </it>(<it>H. pylori</it>) frequently occurs after endoscopic examination of <it>H. pylori</it>-infected patients. In the hospital, manual pre-cleaning and soaking in glutaraldehyde is an important process to disinfect endoscopes. However, this might not be sufficient to remove <it>H. pylori </it>completely, and some glutaraldehyde-resistant bacteria might survive and be passed to the next patient undergoing endoscopic examination through unidentified mechanisms. We identified an Imp/OstA protein associated with glutaraldehyde resistance in a clinical strain, NTUH-C1, from our previous study. To better understand and manage the problem of glutaraldehyde resistance, we further investigated its mechanism.</p> <p>Results</p> <p>The minimal inhibitory concentrations (MICs) of glutaraldehyde andexpression of <it>imp/ostA </it>RNA in 11 clinical isolates from the National Taiwan University Hospital were determined. After glutaraldehyde treatment, RNA expression in the strains with the MICs of 4–10 μg/ml was higher than that in strains with the MICs of 1–3 μg/ml. We examined the full-genome expression of strain NTUH-S1 after glutaraldehyde treatment using a microarray and found that 40 genes were upregulated and 31 genes were downregulated. Among the upregulated genes, <it>imp/ostA </it>and <it>msbA</it>, two putative lipopolysaccharide biogenesis genes, were selected for further characterization. The sensitivity to glutaraldehyde or hydrophobic drugs increased in both of <it>imp/ostA </it>and <it>msbA </it>single mutants. The <it>imp/ostA </it>and <it>msbA </it>double mutant was also hypersensitive to these chemicals. The lipopolysaccharide contents decreased in individual <it>imp/ostA </it>and <it>msbA </it>mutants and dramatically reduced in the <it>imp/ostA </it>and <it>msbA </it>double mutant. Outer membrane permeability assay demonstrated that the <it>imp/ostA </it>and <it>msbA </it>double mutation resulted in the increase of outer membrane permeability. Ethidium bromide accumulation assay demonstrated that MsbA was involved in efflux of hydrophobic drugs.</p> <p>Conclusion</p> <p>The expression levels of <it>imp/ostA </it>and <it>msbA </it>were correlated with glutaraldehyde resistance in clinical isolates after glutaraldehyde treatment. Imp/OstA and MsbA play a synergistic role in hydrophobic drugs resistance and lipopolysaccharide biogenesis in <it>H. pylori</it>.</p
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Paxillin facilitates timely neurite initiation on soft-substrate environments by interacting with the endocytic machinery.
Neurite initiation is the first step in neuronal development and occurs spontaneously in soft tissue environments. Although the mechanisms regulating the morphology of migratory cells on rigid substrates in cell culture are widely known, how soft environments modulate neurite initiation remains elusive. Using hydrogel cultures, pharmacologic inhibition, and genetic approaches, we reveal that paxillin-linked endocytosis and adhesion are components of a bistable switch controlling neurite initiation in a substrate modulus-dependent manner. On soft substrates, most paxillin binds to endocytic factors and facilitates vesicle invagination, elevating neuritogenic Rac1 activity and expression of genes encoding the endocytic machinery. By contrast, on rigid substrates, cells develop extensive adhesions, increase RhoA activity and sequester paxillin from the endocytic machinery, thereby delaying neurite initiation. Our results highlight paxillin as a core molecule in substrate modulus-controlled morphogenesis and define a mechanism whereby neuronal cells respond to environments exhibiting varying mechanical properties
Enhancement of brain-type creatine kinase activity ameliorates neuronal deficits in Huntington's disease
AbstractHuntington's disease (HD) is a hereditary neurodegenerative disorder caused by a CAG repeat expansion in the huntingtin (HTT) gene. Brain-type creatine kinase (CKB) is an enzyme involved in energy homeostasis via the phosphocreatine–creatine kinase system. Although downregulation of CKB was previously reported in brains of HD mouse models and patients, such regulation and its functional consequence in HD are not fully understood. In the present study, we demonstrated that levels of CKB found in both the soma and processes were markedly reduced in primary neurons and brains of HD mice. We show for the first time that mutant HTT (mHTT) suppressed the activity of the promoter of the CKB gene, which contributes to the lowered CKB expression in HD. Exogenous expression of wild-type CKB, but not a dominant negative CKB mutant, rescued the ATP depletion, aggregate formation, impaired proteasome activity, and shortened neurites induced by mHTT. These findings suggest that negative regulation of CKB by mHTT is a key event in the pathogenesis of HD and contributes to the neuronal dysfunction associated with HD. In addition, besides dietary supplementation with the CKB substrate, strategies aimed at increasing CKB expression might lead to the development of therapeutic treatments for HD
Direct growth of ultra-long platinum nanolawns on a semiconductor photocatalyst
A template- and surfactant-free process, thermally assisted photoreduction, is developed to prepare vertically grown ultra-long Pt nanowires (NWs) (about 30-40 nm in diameter, 5-6 μm in length, and up to 80 NWs/100 μm2 in the wire density) on TiO2 coated substrates, including Si wafers and carbon fibers, with the assistance of the photocatalytic ability and semiconductor characteristics of TiO2. A remarkable aspect ratio of up to 200 can be achieved. TEM analytical results suggest that the Pt NWs are single-crystalline with a preferred 〈111〉 growth direction. The precursor adopted and the heat treatment conditions are crucial for the yield of NWs. The photoelectrons supplied by TiO2 gives rise to the formation of nano-sized Pt nuclei from salt melt or solution. The subsequent growth of NWs is supported by the thermal electrons which also generated from TiO2 during the post thermal treatment. The interactions between the ions and the electrons in the Pt/TiO2 junction are discussed in this study
The Effects of Green Energy Production on Farmland: A Case Study in Yunlin County, Taiwan
Taiwan enacted the Act of Renewable Energy in the year 2009 which promotes energy safety, green economy, and a sustainable environment, and with that the government envisages a contribution of photovoltaic energy of up to 20% by the year 2025. In this study we look into the motivation and background of this energy policy, plans for implementation and associated challenges, and its actual consequences for farmland use and farmers. In addition, we take a look into the implementation of mixed-use farmland in which agricultural activity and photovoltaic installations are planned to coexist in order to increase land value and productivity. We furthermore report on some of our findings related to a field survey conducted in Taiwan’s corn chamber of Yunlin County which has been facing a number of socioeconomic challenges
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