Midtropospheric frontogenesis associated with antecedent indirect precipitation ahead of tropical cyclones over the Korean Peninsula

On the Korean Peninsula (KP), heavy rainfall often precedes the landfall of a tropical cyclone (TC). This rainfall is called antecedent indirect precipitation (AIP), because it occurs well beyond the effective radius of the TC. The present study examines the statistical characteristics and physical mechanism of the AIP produced by TCs that influenced the KP during the period 1993-2004. Composite analyses demonstrate that the AIP events were accompanied by midtropospheric frontogenesis due to the TC-mid-latitude environment interaction. When an approaching TC encountered an approaching mid-latitude upper-level trough, this encounter resulted in confluent and deformed flows at the mid-level by the combination of westerlies from the trough and southerlies from the TC. The delicate balance of horizontal winds related to the two systems at the mid-level led to the midtropospheric frontogenesis to the north of the KP. The frontogenetic feature related to the AIP was in marked contrast to those of the remote rainfall event over the KP and the predecessor rainfall event over the United States suggested by previous studies. Quasi-geostrophic analysis demonstrates that the midtropospheric front induced thermally direct circulation, which led to ascending motion over the KP. Consequently, the midtropospheric front helped to intensify the AIP, together with the convective instability that was amplified by the transport of warm and moist air along the conduit between the TC and subtropical high.open110Ysciescopu

Prevalence and awareness of lower urinary tract symptoms among males in the Outpatient Clinics of Universiti Kebangsaan Malaysia Medical Centre.

This study aims to determine the prevalence of lower urinary tract symptoms (LUTS) and level of awareness among male outpatients in Universiti Kebangsaan Malaysia Medical Centre (UKMMC). A questionnaire consisting of demographic data, questions related to knowledge, attitude and practice on BPH and the International Prostate Symptom Score (IPSS) was used for this study. Uroflowmetry and bladder scan were used to evaluate the function of the urinary tract and severity of BPH. Urine dipstick was done for glycosuria, proteinuria and haematuria. A total of 220 respondents were surveyed. The prevalence of moderately and severely symptomatic LUTS was 42.7%. The most commonly reported LUTS were nocturia (78.2%), frequency (58.2%) and incomplete emptying (44.6%). The prevalence of glycosuria, proteinuria and haematuria were 23.6%, 11.4% and 1.8% respectively. There was a significant association between increasing age with the severity of LUTS (p=0.005). Out of 102 respondents with voided urine volume greater than 150 mL, there was a significant decrease in maximum (Qmax) (p=0.039) and average (Qave) urine flow rates with every 10 years increase of age (p=0.001). The majority of respondents (59.5%) have heard of BPH before. Over 78.2% of the respondents would seek medical attention if they have LUTS with 15.9% saying they would seek traditional treatment. In conclusion, the prevalence of LUTS was high and the level of awareness was satisfactory

Transmission electron microscopy and energy dispersive X-ray spectroscopy on the worn surface of nano-structured TiAlN/VN multilayer coating

Nano-structured TiAIN/VN multilayer hard coatings grown by cathodic arc metal ion etching and unbalanced magnetron sputtering deposition have repeatedly shown low coefficients of friction and wear. In this paper, we employed the combined methods of cross-sectional ion beam milling sample preparation, conventional transmission electron microscopy, energy dispersive X-ray spectroscopy and quantitative spectrum analysis to give a comprehensive characterization of wear induced tribofilm, worn TiAIN/VN surface as well as wear debris. The major wear mechanism operating in the TiAIN/VN coating is the tribo-oxidation wear. A 20-50 nm thick tribofilm was observed on the TiAIN/VN worn surface, having inhomogeneous density, amorphous structure and multicomponent V-Al-Ti-O composition. Therefore the real sliding contact during the ball-on-disk test was a three-body sliding system including the tribofilm, in which the self-sintering and shearing deformation of the multicomponent oxide film played a significant role in determining the low friction coefficient. Owing to the low friction and high hardness, the TiAIN/VN worn surface retained good structural integrity without any crack, delamination or detectable deformation, resulting in minimized mechanical wear. (c) 2005 Elsevier B.V. All rights reserved

Measurement of the emission spectrum of a semiconductor laser using laser-feedback interferometry

The effects of optical feedback (OF) in lasers have been observed since the early days of laser development. While OF can result in undesirable and unpredictable operation in laser systems, it can also cause measurable perturbations to the operating parameters, which can be harnessed for metrological purposes. In this work we exploit this ‘self-mixing’ effect to infer the emission spectrum of a semiconductor laser using a laser-feedback interferometer, in which the terminal voltage of the laser is used to coherently sample the reinjected field. We demonstrate this approach using a terahertz frequency quantum cascade laser operating in both single- and multiple-longitudinal mode regimes, and are able to resolve spectral features not reliably resolved using traditional Fourier transform spectroscopy. We also investigate quantitatively the frequency perturbation of individual laser modes under OF, and find excellent agreement with predictions of the excess phase equation central to the theory of lasers under OF

Laser feedback interferometry with THz QCLs: A new technology for imaging and materials analysis

Considerable interest exists for sensing and imaging technologies in the terahertz (THz) spectral range, in particular for the interrogation of materials of an organic or biological nature. Development in THz quantum cascade lasers is seeing higher operating temperatures and peak output powers in pulsed mode, accentuating their place as the preferred source of coherent THz frequency radiation. Technological development of interferometric sensing schemes continues to take advantage of practical improvements in THz quantum cascade lasers. In this Summary, we give a brief overview of some recent developments in this regard

Origin of terminal voltage variations due to self-mixing in a terahertz frequency quantum cascade laser

The use of quantum cascade lasers (QCLs) for laser feedback interferometry (LFI) has received significant attention since it enables a wide range of sensing applications without requiring a separate detector, and hence simplifies experimental apparatus [1]. LFA (based on the self-mixing effect) refers to the partial reinjection of the radiation emitted from a laser after reflection from a target; the injected radiation field then interacts with the intra-cavity field causing measurable variations of the QCL terminal voltage. The theory of LFI with conventional laser sources is well studied and explained by the Lang–Kobayashi model [2, 3]. However, while this enables the dynamic state populations and light interaction to be modelled, a linear relationship between the change in cavity light power, ∆P, and terminal voltage variation is commonly assumed, i.e. VSM ∝ ∆P [4, 5]. This is not strictly applicable to QCL structures since carrier transport is dominated by the mechanisms of electron subband alignment, intersubband scattering and photon driven transport between subbands with energy separations that change with applied bias (terminal voltage). We present experimental results of a QCL which departs significantly from this assumed linear behavior. We observe strong enhancement of the self-mixing signal in regions where the local gradient of the current-voltage (I–V) curve increases. We explain the origin of this signal using an extended density matrix (DM) approach [6] which accounts for coherent transport and interaction of the optical light field with the active region. The model is used to calculate the I–V characteristics of a bound-to-continuum (BTC) terahertz (THz) QCL and predict the effect of light variation on terminal voltage at a fixed drive current. This approach is shown to predict the experimental signal with good agreement

The predictive and prognostic potential of plasma telomerase reverse transcriptase (TERT) RNA in rectal cancer patients

Background: Preoperative chemoradiotherapy (CRT) followed by surgery is the standard care for locally advanced rectal cancer, but tumour response to CRT and disease outcome are variable. The current study aimed to investigate the effectiveness of plasma telomerase reverse transcriptase (TERT) levels in predicting tumour response and clinical outcome. Methods: 176 rectal cancer patients were included. Plasma samples were collected at baseline (before CRT\ubcT0), 2 weeks after CRT was initiated (T1), post-CRT and before surgery (T2), and 4\u20138 months after surgery (T3) time points. Plasma TERT mRNA levels and total cell-free RNA were determined using real-time PCR. Results: Plasma levels of TERT were significantly lower at T2 (Po0.0001) in responders than in non-responders. Post-CRT TERT levels and the differences between pre- and post-CRT TERT levels independently predicted tumour response, and the prediction model had an area under curve of 0.80 (95% confidence interval (CI) 0.73\u20130.87). Multiple analysis demonstrated that patients with detectable TERT levels at T2 and T3 time points had a risk of disease progression 2.13 (95% CI 1.10\u20134.11)-fold and 4.55 (95% CI 1.48\u201313.95)-fold higher, respectively, than those with undetectable plasma TERT levels. Conclusions: Plasma TERT levels are independent markers of tumour response and are prognostic of disease progression in rectal cancer patients who undergo neoadjuvant therapy