Structural Forecasts for the Danish Economy Using the Dynamic-AAGE Model

We describe how an applied dynamic general equilibrium model of the Danish economy has been developed to generate structural forecasts. The forecasts provide a microeconomic picture that is consistent with a macroeconomic scenario and the other inputs. We provide an overview of the inputs required to generate the forecasts and of the forecast methodology. Finally, we present aspects of the forecasting results.Research and Development/Tech Change/Emerging Technologies,

Predicting Reinforcers to Increase Physical Activity in Young Children with Obesity using the Six-Minute Walk Test

Childhood obesity continues to be a significant public health problem in the United States in which approximately 8% to 12% of American children are obese (Cunningham, Kramer, & Narayan, 2014; Mirza et al., 2018; Ogden et al., 2014). Further, 42% of American children are engaging in less than the recommended 60 minutes of daily physical activity (Troiano et al., 2008). Several treatments have been evaluated that have included goal-setting, self-monitoring, performance feedback, and access to arbitrary tangible rewards (e.g., Hyusti, Normand, & Larson, 2011; Van Camp & Hayes, 2012), but these treatments have often failed Luttikhuis et al., 2009; Nooijan et al., 2017). Successfully identifying reinforcers for physical activity may lead to an increase in treatment successes in young children with obesity. Previous studies that evaluated procedures to predict reinforcement of physical activity have notably neglected the participation of children with obesity. In addition, previous studies have not included tangible stimuli as possible reinforcers for increasing physical activity. The current study evaluated modifications to the Six-Minute Walk Test (6MWT, American Thoracic Society, 2002) to predict individualized reinforcers of physical activity in young children with obesity. Reinforcers identified through these procedures were then compared to arbitrarily identified rewards. Three children with obesity between five and nine years old participated in the study. Results demonstrated that using the modified 6MWT as a reinforcer analysis predicted individualized reinforcers that increased physical activity beyond baseline levels, and identified reinforcers that were more effective than arbitrarily-selected rewards. Future research implications and limitations are discussed

Response of the Agile Antechinus to Habitat Edge, Configuration and Condition in Fragmented Forest

Habitat fragmentation and degradation seriously threaten native animal communities. We studied the response of a small marsupial, the agile antechinus Antechinus agilis, to several environmental variables in anthropogenically fragmented Eucalyptus forest in south-east Australia. Agile antechinus were captured more in microhabitats dominated by woody debris than in other microhabitats. Relative abundances of both sexes were positively correlated with fragment core area. Male and female mass-size residuals were smaller in larger fragments. A health status indicator, haemoglobin-haematocrit residuals (HHR), did not vary as a function of any environmental variable in females, but male HHR indicated better health where sites' microhabitats were dominated by shrubs, woody debris and trees other than Eucalyptus. Females were trapped less often in edge than interior fragment habitat and their physiological stress level, indicated by the neutrophil/lymphocyte ratio in peripheral blood, was higher where fragments had a greater proportion of edge habitat. The latter trend was potentially due to lymphopoenia resulting from stress hormone-mediated leukocyte trafficking. Using multiple indicators of population condition and health status facilitates a comprehensive examination of the effects of anthropogenic disturbances, such as habitat fragmentation and degradation, on native vertebrates. Male agile antechinus' health responded negatively to habitat degradation, whilst females responded negatively to the proportion of edge habitat. The health and condition indicators used could be employed to identify conservation strategies that would make habitat fragments less stressful for this or similar native, small mammals

Metabolic Heat: A New Way of Looking at How Controlled Atmospheres Kill Insects

The use of calorimetry as a tool to understand the effects of controlled atmospheres (CA) on insects is briefly reviewed. A variety of data are presented to illustrate the various types of information that calorimetry can make available to researchers. The use of a calorimeter connected to a mass spectrometer to determine the occurrence of anaerobic respiration is described and reported. We conclude that calorimetry is a useful tool to simplify the experimental options when developing new insecticidal CA treatments. It can also be used for development of other treatments such as fumigants

Coping with stress in the workplace

The researchers investigated a simplified process model, a so-called salutogenic approach, of coping with stress in the workplace. Two constructs of salutogenic functioning, namely sense of coherence and locus of control (three dimensions: internal, external locus and autonomy), as well as the stress levels of 240 employees from a parastatal organisation were measured. As expected, individuals with a stronger sense of coherence and a stronger internal locus of control experienced lower levels of stress and vice versa. Nevertheless, in a regression analysis only the sense of coherence and external locus of control variables contributed significantly to variance in the criterion variable stress

Boundary Conditions on Internal Three-Body Wave Functions

For a three-body system, a quantum wave function $\Psi^\ell_m$ with definite $\ell$ and $m$ quantum numbers may be expressed in terms of an internal wave function $\chi^\ell_k$ which is a function of three internal coordinates. This article provides necessary and sufficient constraints on $\chi^\ell_k$ to ensure that the external wave function $\Psi^\ell_m$ is analytic. These constraints effectively amount to boundary conditions on $\chi^\ell_k$ and its derivatives at the boundary of the internal space. Such conditions find similarities in the (planar) two-body problem where the wave function (to lowest order) has the form $r^{|m|}$ at the origin. We expect the boundary conditions to prove useful for constructing singularity free three-body basis sets for the case of nonvanishing angular momentum.Comment: 41 pages, submitted to Phys. Rev.

Negative Feedback Regulation of the Yeast Cth1 and Cth2 mRNA Binding Proteins Is Required for Adaptation to Iron Deficiency and Iron Supplementation

Iron (Fe) is an essential element for all eukaryotic organisms because it functions as a cofactor in a wide range of biochemical processes. Cells have developed sophisticated mechanisms to tightly control Fe utilization in response to alterations in cellular demands and bioavailability. In response to Fe deficiency, the yeast Saccharomyces cerevisiae activates transcription of the CTH1 and CTH2 genes, which encode proteins that bind to AU-rich elements (AREs) within the 3′ untranslated regions (3′UTRs) of many mRNAs, leading to metabolic reprogramming of Fe-dependent pathways and decreased Fe storage. The precise mechanisms underlying Cth1 and Cth2 function and regulation are incompletely understood. We report here that the Cth1 and Cth2 proteins specifically bind in vivo to AREs located at the 3′UTRs of their own transcripts in an auto- and cross-regulated mechanism that limits their expression. By mutagenesis of the AREs within the CTH2 transcript, we demonstrate that a Cth2 negative-feedback loop is required for the efficient decline in Cth2 protein levels observed upon a rapid rise in Fe availability. Importantly, Cth2 autoregulation is critical for the appropriate recovery of Fe-dependent processes and resumption of growth in response to a change from Fe deficiency to Fe supplementation

A thermostable enzyme as an experimental platform to study properties of less stable homologues.

The structural and functional characterization of proteins is frequently hampered by lack of stability or by insufficient assembly of oligomeric proteins in over-expression systems. Using