391 research outputs found
Linear preservers and quantum information science
Let be positive integers, the set of complex
matrices and the set of complex matrices. Regard as
the tensor space . Suppose is the Ky Fan -norm
with , or the Schatten -norm with
() on . It is shown that a linear map satisfying for all
and if and only if there are unitary such that
has the form ,
where is either the identity map or the
transposition map . The results are extended to tensor space
of higher level. The connection of the
problem to quantum information science is mentioned.Comment: 13 page
Physical transformations between quantum states
Given two sets of quantum states {A_1, ..., A_k} and {B_1, ..., B_k},
represented as sets of density matrices, necessary and sufficient conditions
are obtained for the existence of a physical transformation T, represented as a
trace-preserving completely positive map, such that T(A_i) = B_i for i = 1,
..., k. General completely positive maps without the trace-preserving
requirement, and unital completely positive maps transforming the states are
also considered
Dommages à I' ADN induits par les électrons de basse énergie : l'analyse des produits et études des mécanismes de dommage dans des oligonucleotides courts
L'objectif majeur de notre groupe de recherche est de comprendre le mécanisme de dommage à l' ADN induit par les électrons de basse énergie "secondaire" provenant de radiations ionisantes et sa relation avec la radiosensibilité et la radiothérapie. Le professeur Sanche a développé un nouveau système d'irradiation d'électron de basse énergie avec lequel une relativement grande surface constituée de couches minces d' ADN peut être irradiée avec des électrons mono-énergétiques sous hyper-vide. Ceci permet l'irradiation de l' ADN ciblé et la formation d'une quantité suffisamment grande d' ADN endommagé pour effectuer des analyses chimiques (HPLC, GC/MS et LC/MS-MS) sur les produits générés et ainsi élucider le mécanisme de dommage à l' ADN par les électrons de basse énergie. Mon projet se concentre sur les systèmes simples, dans lesquels des nucléosides ( dThd), nucléotides (pT, Tp et pTp ), oligonucléotides (TT et TTT) et des oligonucléotides modifiés (TSBrUT) sont exposés à des électrons de basse énergie. Les réactions subséquentes sont étudiées par analyses chimiques des produits formés. Mes études ont révélé trois mécanismes de fragmentation dans l' ADN induits par les électrons de basse énergie : 1) le groupe phosphate terminal a une plus large section efficace dans les dommages induits par les électrons de basse énergie; 2) la capture initiale des électrons de basse énergie et le bris de lien subséquent dans l'anion intermédiaire dépend de la séquence et de l'affinité des électrons de la base; 3) à 10 eV, un électron peut induire un événement double. La présente étude fourni une base chimique de la formation de bris par la réaction des électrons de basse énergie avec l'ADN.Abstract: The major objective of our group is to understand the mechanism of DNA damage induced by secondary low-energy electrons (LEE) arising from ionizing radiation and its relationship to radiosensitization and radiotherapy. Prof. Sanche has developed a novel low-energy electron irradiation system in which a relatively large area of thin films of DNA constituents can be irradiated with mono-energetic electrons under ultra high vacuum. This permits the irradiation of target DNA and the formation of sufficient degraded material to allow for chemical analysis (HPLC, GC/MS, and LC/MS/MS) of products remaining on the target surface, so as to elucidate the mechanism of LEE-induced DNA damage. My project focuses on simple systems, in which small DNA components nucleosides (dThd), nucleotides (pT, Tp, pTp), oligonucleotides (TT and TTT) and modified oligonucleotides (T5BrUT) are exposed to low-energy electrons, and the subsequent reactions are studied by chemical analysis of the products. My studies revealed three mechanisms of LEE-induced fragmentation reactions in DNA: 1) the terminal phosphate group has a larger cross-section in LEE-induced DNA damage; 2) initial LEE capture and subsequent bond breaking within the intermediate anion depend on the sequence and electron affinity of the bases; and 3) at 10 eV, one electron might induce double events. This study provides a chemical basis for the formation of DNA strand breaks by the interaction of LEE with DNA
Human Microbe-Disease Association Prediction With Graph Regularized Non-Negative Matrix Factorization
A microbe is a microscopic organism which may exists in its single-celled form or in a colony of cells. In recent years, accumulating researchers have been engaged in the field of uncovering microbe-disease associations since microbes are found to be closely related to the prevention, diagnosis, and treatment of many complex human diseases. As an effective supplement to the traditional experiment, more and more computational models based on various algorithms have been proposed for microbe-disease association prediction to improve efficiency and cost savings. In this work, we developed a novel predictive model of Graph Regularized Non-negative Matrix Factorization for Human Microbe-Disease Association prediction (GRNMFHMDA). Initially, microbe similarity and disease similarity were constructed on the basis of the symptom-based disease similarity and Gaussian interaction profile kernel similarity for microbes and diseases. Subsequently, it is worth noting that we utilized a preprocessing step in which unknown microbe-disease pairs were assigned associated likelihood scores to avoid the possible negative impact on the prediction performance. Finally, we implemented a graph regularized non-negative matrix factorization framework to identify potential associations for all diseases simultaneously. To assess the performance of our model, cross validations including global leave-one-out cross validation (LOOCV) and local LOOCV were implemented. The AUCs of 0.8715 (global LOOCV) and 0.7898 (local LOOCV) proved the reliable performance of our computational model. In addition, we carried out two types of case studies on three different human diseases to further analyze the prediction performance of GRNMFHMDA, in which most of the top 10 predicted disease-related microbes were verified by database HMDAD or experimental literatures
On the second-order zero differential spectra of some power functions over finite fields
Boukerrou et al. (IACR Trans. Symmetric Cryptol. 2020(1), 331-362) introduced
the notion of Feistel Boomerang Connectivity Table (FBCT), the Feistel
counterpart of the Boomerang Connectivity Table (BCT), and the Feistel
boomerang uniformity (which is the same as the second-order zero differential
uniformity in even characteristic). FBCT is a crucial table for the analysis of
the resistance of block ciphers to power attacks such as differential and
boomerang attacks. It is worth noting that the coefficients of FBCT are related
to the second-order zero differential spectra of functions. In this paper, by
carrying out certain finer manipulations of solving specific equations over the
finite field , we explicitly determine the second-order zero
differential spectra of some power functions with low differential uniformity,
and show that our considered functions also have low second-order zero
differential uniformity. Our study pushes further former investigations on
second-order zero differential uniformity and Feistel boomerang differential
uniformity for a power function
Conductivity measurement of ionic liquids confined in the nanopores of metal–organic frameworks: a case study for [BMIM][TFSI] in HKUST-1
Nanoporous materials like metal–organic frameworks (MOFs) attract considerable attention as porous host for electrolytes like ionic liquids (ILs). The conductivity and mobility of the ions in the pores are among the key properties and their experimental quantification is of paramount importance. Here, three different approaches for the quantification of the ion conductivity of IL@MOF via electrochemical impedance spectroscopy (EIS) are compared: the material in the form of IL-impregnated MOF powders pressed into pellets between two planar electrodes, MOF films grown on substrates with deposited electrodes loaded with IL by impregnation, and the IL-loaded MOF films where excess IL is removed. Contact-angle measurements and EIS data show that the excess IL on the outer MOF surface of the film or pellet results in apparent conductivities, larger than the intrinsic conductivity of the IL@MOF. Removing the excess IL enables the experimental quantification of the intrinsic IL@MOF conductivity
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