A survey on intelligence-endogenous network: Architecture and technologies for future 6G

With the maturity of 5G technology and global commercialization, scholars in institutions and industrial circles began to research 6G technology. An important innovation of 6G technology is to integrate artificial intelligence (AI) technology and communication technology to build a highly endogenous intelligent communication network. This paper investigates the process of AI technology introduced into the field of communication and reviews the use cases of the simulation and application of AI algorithms being discussed in 3GPP meetings in industry circles. In this research report, we first investigate the progress of AI technology in 5G network architecture and then discuss the requirements of endogenous intelligent 6G networks, which leads to the possible network architecture. This work aims to provide enlightening guidance for subsequent research of intelligence-endogenous 6G network

Production of Glycopeptide Derivatives for Exploring Substrate Specificity of Human OGA Toward Sugar Moiety.

O-GlcNAcase (OGA) is the only enzyme responsible for removing N-acetyl glucosamine (GlcNAc) attached to serine and threonine residues on proteins. This enzyme plays a key role in O-GlcNAc metabolism. However, the structural features of the sugar moiety recognized by human OGA (hOGA) remain unclear. In this study, a set of glycopeptides with modifications on the GlcNAc residue, were prepared in a recombinant full-length human OGT-catalyzed reaction, using chemoenzymatically synthesized UDP-GlcNAc derivatives. The resulting glycopeptides were used to evaluate the substrate specificity of hOGA toward the sugar moiety. This study will provide insights into the exploration of probes for O-GlcNAc modification, as well as a better understanding of the roles of O-GlcNAc in cellular physiology

Effects of magnanimous therapy on emotional, psychosomatic and immune functions of lung cancer patients

This study was a randomised controlled study on the effects of the individual computer magnanimous therapy and group computer magnanimous therapy on emotional, psychosomatic and immune function among advanced lung cancer patients. Patients were examined at baseline and 2 weeks later using the Psychosomatic Status Scale for Cancer Patients, Hospital Anxiety Depression Scale and IgA, IgG, IgM and natural killer cell functions. The results showed that individual computer magnanimous therapy and group computer magnanimous therapy were beneficial for advanced lung cancer patients in improving depression, anxiety, psychosomatic status and immune functions. The improvements of immune functions may be related to the improvements of the participants’ emotional and psychosocial status

Acclimation of photosystem II to high temperature in two Wedelia species from different geographical origins: implications for biological invasions upon global warming

More intense, more frequent, and longer heat waves are expected in the future due to global warming, which could have dramatic ecological impacts. However, few studies have involved invasive species. The aims of this study were to examine the effect of extreme heating (40/35°C for 30d) on the growth and photosynthesis of an alien invasive species Wedelia trilobata and its indigenous congener (Wedelia chinensis) in South China, and to determine the development of this invasive species and its potential adaptive mechanism. In comparison with W. chinensis, W. trilobata suffered less inhibition of the relative growth rate (RGR) and biomass production due to high temperature, which was consistent with the changes of photosystem II (PSII) activity and net photosynthetic rate (Pn). High temperature caused a partial inhibition of PSII, but the adverse effect was more severe in W. chinensis. Measurement of the minimum fluorescence (Fo) versus temperature curves showed that W. trilobata had a higher inflexion temperature of Fo (Ti), indicating greater thermostability of the photosynthetic apparatus. Moreover, comparisons of absorbed light energy partitioning revealed that W. trilobata increased xanthophyll-dependent thermal dissipation (ΦNPQ) under high temperature, while retaining the higher fraction of absorbed light allocated to photochemistry (ΦPSII) relative to W. chinensis. The results suggest that the invasive W. trilobata has a high thermostability of its photosynthetic apparatus and an effective regulating mechanism in energy partitioning of PSII complexes to minimize potential damage and to retain greater capability for carbon assimilation. These factors confer greater heat stress tolerance compared with the native species. Therefore, the invasive W. trilobata may become more aggressive with the increasingly extreme heat climates

Nurse-led cognitive screening model for older adults in primary care

Author version made available in accordance with publisher copyright. Under 12 month embargo from date of publication [26 September 2014]. This is the accepted version of the following article: [Yang, Y., Xiao, L. D., Deng, L., Wang, Y., Li, M. and Ullah, S. (2014), Nurse-led cognitive screening model for older adults in primary care. Geriatrics & Gerontology International.], which has been published in final form at [doi: 10.1111/ggi.12339]. In addition, authors may also transmit, print and share copies with colleagues, provided that there is no systematic distribution of the submitted version, e.g. posting on a listserve, network or automated delivery.Aim The present study aimed to establish a nurse-led cognitive screening model for community-dwelling older adults with subjective memory complaints from seven communities in Chongqing, China, and report the findings of this model. Methods Screenings took place from July 2012 to June 2013. Cognitive screening was incorporated into the annual health assessment for older adults with subjective memory complaints in a primary care setting. Two community nurses were trained to implement the screening using the Mini-Mental State Examination and Montreal Cognitive Assessment. Results Of 733 older adults, 495 (67.5%) reported having subjective memory complaints. Of the 249 individuals who participated in the cognitive screening, 102 (41%) had mild cognitive impairment, whereas 32 (12.9%) had cognitive impairment. A total of 80 participants (78.4%) with mild cognitive impairment agreed to participate in a memory support program. Participants with cognitive impairment were referred to specialists for further examination and diagnosis; only one reported that he had seen a specialist and had been diagnosed with dementia. Conclusions Incorporating cognitive screening into the annual health assessment for older adults with subjective memory complaints was feasible, though referral rates from primary care providers remained unchanged. The present study highlights the urgent need for simple screenings as well as community-based support services in primary care for older adults with cognitive or mild cognitive impairments

Theoretical study on structural properties and 4f 5d transitions of locally charge-compensated Ce3+ in CaF2

Reprinted with permission from Ning, L., Wu, C.,Li, L., Lin,L., Duan, C., Zhang, Y. and Luis Seijo. "Theoretical study on structural properties and 4f 5d transitions of locally charge-compensated Ce3+ in CaF2". The Journal of Physical Chemistry C 116.34 (2012): 18419-18426.The structural properties and 4f → 5d transitions of Ce3+ in CaF2, with local charge compensation by an interstitial fluoride (Fi ′) or an oxygen substitution for fluoride (OF′), have been studied using the density functional theory (DFT) within the supercell model and the wave function-based embedded cluster calculations, respectively. The DFT results indicate that the incorporation of locally charge-compensated Ce3+ in CaF2 induces an anisotropic distortion of the structure around the dopant site. On the basis of the DFToptimized structures, the Ce-centered embedded clusters are constructed, on which the wave function-based CASSCF/CASPT2/ RASSI−SO calculations at the spin−orbit level are performed to obtain the Ce3+ 4f1 and 5d1 level energies. The calculated 4f−5d transition energies and relative intensities are in good agreement with available experimental results. From the present calculations, we conclude that the 5d1 level missing in the low-temperature absorption spectrum of the tetragonal Ce center with Fi ′ compensation is the second-lowest one, and the absorption at this level is overshadowed by an adjacent cluster band usually assigned to Ce clusters and thus was not observed in experiments. We also assign the two closely spaced absorption lines around 3118.5 Å observed in experiments to the lowest two quasi-degenerated 4f → 5d transitions of the monoclinic center with Fi ′ compensation rather than those of the trigonal center as proposed earlier. Finally, we analyze the structural and electronic reasons for the large reduction (∼2000 cm−1 ) of the lowest 4f → 5d transition energy from a Fi ′ to a nearest-neighbor OF′ compensation, in terms of the changes in the centroid energy difference and crystal- field splittingThis work was supported by the NSFC (Grants 11174005, 11074315, 90922022, and 10804001) and the Program for Innovative Research Teams in Anhui Normal University of China. L.S. acknowledges support from MEC-Spain (Grant MAT2011-24586

Electronic properties and 4f→ 5d transitions in Ce-doped Lu2SiO5: a theoretical investigation

This is an electronic version of an article published in Journal of Materials Chemistry. Ning, L., Lin, L., Li, L., Wu, C., Duan, C., Zhang, Y. and Luis Seijo. "Electronic properties and 4f 5d transitions in Ce-doped Lu2SiO5: a theoretical investigation". Journal of Materials Chemistry 22 (2012): 13723-1373

A broad-host-range lytic phage vB_VhaS-R18L as a candidate against vibriosis

Vibriosis is one of the most common bacterial diseases that cause high rates of mortality and considerable economic losses in aquaculture. Phage therapy has been considered as a promising alternative method to antibiotics in the biocontrol of infectious diseases. Genome sequencing and characterization of the phage candidates are prerequisites before field applications to ensure environmental safety. In this study, a lytic phage, named vB_VhaS-R18L (R18L), was isolated from the coastal seawater of Dongshan Island, China. The phage was characterized in terms of morphology, genetic content, infection kinetics, lytic profile, and virion stability. Transmission electronic microscopy indicated that R18L is siphovirus-like, comprising an icosahedral head (diameter 88.6 ± 2.2 nm) and a long noncontractile tail (225 × 11 nm). Genome analysis indicated R18L to be a double-stranded DNA virus with a genome size of 80,965 bp and a G + C content of 44.96%. No genes that encode known toxins or genes implicated in lysogeny control were found in R18L. A one-step growth experiment showed that R18L had a latent period of approximately 40 min and a burst size of 54 phage particles per infected cell. R18L showed lytic activity against a wide range of at least five Vibrio species (V. alginolyticus, V. cholerae, V. harveyi, V. parahemolyticus, and V. proteolyticus). R18L was relatively stable at pH 6–11 and at temperatures ranging from 4°C to 50°C. The broad lytic activity across Vibrio species and the stability in the environment make R18L a potential candidate for phage therapy in controlling vibriosis in aquaculture systems

Comparative antiseizure medications of adjunctive treatment for children with drug-resistant focal-onset seizures: A systematic review and network meta-analysis

Purpose: In this study, we intended to compare and rank the efficacy and acceptability of antiseizure medications (ASMs) for adjunctive treatment of children with drug-resistant focal-onset seizures.Method: We conducted a computerized search of PubMed, EMBASE, Cochrane Library, Web of Science, and Google Scholar to identify eligible randomized controlled trials (RCTs) published before 31 May 2022. We included studies evaluating the efficacy and tolerability of antiseizure medications for children with drug-resistant focal-onset seizures. The efficacy and safety were reported in terms of responder and dropout rate along with serious adverse events, the outcomes were ranked with the surface under the cumulative ranking curve (SUCRA).Results: A total of 14 studies (16 trials) with 2,464 patients were included, involving 10 active antiseizure medications. For the primary endpoint of at least 50% reduction in focal-onset seizures, the surface under the cumulative ranking curve ranking suggested that lamotrigine and levetiracetam were more effective as compared with other antiseizure medications; moreover, levetiracetam had the highest probability of rank first for achieving seizure freedom. Concerning tolerability, oxcarbazepine and eslicarbazepine acetate were associated with higher dropout rates relative to other antiseizure medications and placebo, and topiramate was associated with higher occurrence of side effects. No significant differences were found between active antiseizure medications concerning dropout for side effects.Conclusion: According to the surface under the cumulative ranking curve ranking, lamotrigine, levetiracetam, and oxcarbazepine were more efficacious than other active antiseizure medications in terms of responder rate. Concerning tolerability, oxcarbazepine was more likely to lead to dropout and topiramate was associated with higher occurrence of side effects