6,793 research outputs found

    Are joint torque models limited by an assumption of monoarticularity?

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    This study determines whether maximal voluntary ankle plantar flexor torque could be more accurately represented using a torque generator that is a function of both knee and ankle kinematics. Iso velocity and isometric ankle plantar flexor torques were measured on a single participant for knee joint angles of 111° to 169° (approximately full extension) using a Contrex M J dynamometer. Maximal voluntary torque was represented by a 19-parameter two-joint function of ankle and knee joint angles and angular velocities with the parameters determined by minimizing a weighted root mean square difference between measured torques and the two-joint function. The weighted root mean square difference between the two-joint function and the measured torques was 10 N-m or 3% of maximum torque. The two-joint function was a more accurate representation of maximal voluntary ankle plantar flexor torques than an existing single-joint function where differences of 19% of maximum torque were found. It is concluded that when the knee is flexed by more than 40°, a two-joint representation is necessary

    An isovelocity dynamometer method to determine monoarticular and biarticular muscle parameters

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    This study aimed to determine whether subject-specific individual muscle models for the ankle plantar flexors could be obtained from single joint isometric and isovelocity maximum torque measurements in combination with a model of plantar flexion. Maximum plantar flexion torque measurements were taken on one subject at six knee angles spanning full flexion to full extension. A planar three-segment (foot, shank and thigh), two muscle (soleus and gastrocnemius) model of plantar flexion was developed. Seven parameters per muscle were determined by minimizing a weighted root mean square difference (wRMSD) between the model output and the experimental torque data. Valid individual muscle models were obtained using experimental data from only two knee angles giving a wRMSD score of 16 N m, with values ranging from 11 to 17 N m for each of the six knee angles. The robustness of the methodology was confirmed through repeating the optimization with perturbed experimental torques (±20%) and segment lengths (±10%) resulting in wRMSD scores of between 13 and 20 N m. Hence, good representations of maximum torque can be achieved from subject-specific individual muscle models determined from single joint maximum torque measurements. The proposed methodology could be applied to muscle-driven models of human movement with the potential to improve their validity

    The dependence of protostar formation on the geometry and strength of the initial magnetic field

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    Published onlineThis is the final version of the article. Available from Oxford University Press via the DOI in this record.We report results from 12 simulations of the collapse of a molecular cloud core to form one or more protostars, comprising three field strengths (mass-to-flux ratios, μ, of 5, 10 and 20) and four field geometries (with values of the angle between the field and rotation axes, ϑ, of 0°, 20°, 45° and 90°), using a smoothed particle magnetohydrodynamics method. We find that the values of both parameters have a strong effect on the resultant protostellar system and outflows. This ranges from the formation of binary systems when μ = 20 to strikingly differing outflow structures for differing values of ϑ, in particular highly suppressed outflows when ϑ = 90°. Misaligned magnetic fields can also produce warped pseudo-discs where the outer regions align perpendicular to the magnetic field but the innermost region re-orientates to be perpendicular to the rotation axis. We follow the collapse to sizes comparable to those of first cores and find that none of the outflow speeds exceed 8 km s−1. These results may place constraints on both observed protostellar outflows and also on which molecular cloud cores may eventually form either single stars or binaries: a sufficiently weak magnetic field may allow for disc fragmentation, whilst conversely the greater angular momentum transport of a strong field may inhibit disc fragmentation.BTL acknowledges support from an STFC Studentship and Long Term Attachment grant. This work was also supported by the European Research Council under the European Community's Seventh Framework Programme (FP7/2007-2013 Grant Agreement No. 339248). MRB's visit to Monash was funded by an International Collaboration Award from the Australian Research Council (ARC) under the Discovery Project scheme grant DP130102078. This work used the DiRAC Complexity system, operated by the University of Leicester IT Services, which forms part of the STFC DiRAC HPC Facility (www.dirac.ac.uk). This equipment is funded by BIS National E-Infrastructure capital grant ST/K000373/1 and STFC DiRAC Operations grant ST/K0003259/1. DiRAC is part of the National E-Infrastructure. Calculations were also performed on the University of Exeter Supercomputer, a DiRAC Facility jointly funded by STFC, the Large Facilities Capital Fund of BIS and the University of Exeter. This work also made use of the NumPy (van der Welt, Colbert & Varoquax 2011) and Matplotlib (Hunter 2007) Python modules. Rendered plots were produced using the splash (Price 2007) visualization program

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    Creating seating plans: A practical application

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    © 2016 Operational Research Society Ltd. All rights reserved. 0160-5682/16. This paper examines the interesting problem of designing seating plans for large events such as weddings and gala dinners where, among other things, the aim is to construct solutions where guests are sat on the same tables as friends and family, but, perhaps more importantly, are kept away from those they dislike. This problem is seen to be N P-complete from a number of different perspectives. We describe the problem model and heuristic algorithm that is used on the commercial website www.weddingseatplanner.com. We present results on the performance of this algorithm, demonstrating the factors that can influence run time and solution quality, and also present a comparison with an equivalent IP model used in conjunction with a commercial solver

    Report on the 2018 trials of the multistatic NeXtRAD dual band polarimetric radar

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    NeXtRAD is a polarimetric, L and X Band, multistatic (three nodes), pulse Doppler radar, developed by UCT and UCL, as a follow on to the NetRAD sensor. This paper reports on the trials carried out in 2018, mostly in Simon's Bay, South Africa. The sensors (one active, two passive) are connected by WiFi communications link, with a maximum separation of 40 km. Practically, results are reported with 8 km maximum baselines. The focus is on targets in sea clutter and micro-Doppler. We report on the final integration and test of the system command and control system that allows for scheduling of measurement and recording of bursts of pulses, as well as video of the radar field of view. Some innovations have been made in terms of digital hardware, firmware, and high performance computing technology. The system is synchronised with the UCT GPS Disciplined Oscillators (one per node), but we also report on bistatic measurements with White Rabbit, fibre timing system, as well as the consequences of GPS failure (GPS Denied Environment)

    Parameterized lower bound and NP-completeness of some HH-free Edge Deletion problems

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    For a graph HH, the HH-free Edge Deletion problem asks whether there exist at most kk edges whose deletion from the input graph GG results in a graph without any induced copy of HH. We prove that HH-free Edge Deletion is NP-complete if HH is a graph with at least two edges and HH has a component with maximum number of vertices which is a tree or a regular graph. Furthermore, we obtain that these NP-complete problems cannot be solved in parameterized subexponential time, i.e., in time 2o(k)GO(1)2^{o(k)}\cdot |G|^{O(1)}, unless Exponential Time Hypothesis fails.Comment: 15 pages, COCOA 15 accepted pape

    RNA sequencing and machine learning as molecular scalpels

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