The Challenge to Democratic Reformism in Ecuador

Ecuador is a small and misdeveloped country that has recently embarked on an important experiment in national development. The nature and outcome of this experiment have implications not only for the social science researcher, but more importantly for the Ecuadorean people themselves and for developing countries in the region and throughout the hemisphere. The administration elected in 1979 has pledged to carry out a program of far-reaching reform within a democratic framework that will harmonize economic development and social justice in a way designed to effect a major transformation of the basic structures and values of the nation. It is clear that the reforms proposed will clash with the country\u27s entrenched heritage of three centuries of unequal social and economic growth and with a political tradition characterized by autocracy and authoritarianism. Many observers wonder whether sufficient resources of any kind can be mobilized during the four years of the current regime even to begin to overcome the inertia of imbalanced development, attributed by some to the forces of dependency and by others to structural rigidities inherent in the social relations of production. l On the other hand, it is true that the conditions in Ecuador today could not be more propitious to initiate a process of significant transformation: unprecedented revenues from petroleum provide the state with a promising resource base for reform, the government is led by a new generation of men who have a profound awareness of the country\u27s past and of its present problems, the administration is staffed by a corps of able men and women freed from the sterile conflicts that once dominated the rhetoric (if not the reality) of national politics, and the economy has a potential for diversification that could provide a base for independent development. How the current regime capitalizes on these favorable circumstances, its success or failure in achieving the goals of development and justice, might provide clues to a clearer analysis of the causes of misdevelopment and to a clearer understanding of the solutions needed to resolve the development crises that plague countries throughout the Third World

Symposium: Giving Korematsu v. United States A Sober Second Thought

We are elated to present Professor Mark Killenbeck’s thought provoking article, Sober Second Thought? Korematsu Reconsidered. Killenbeck dives into the Korematsu opinion and its history with great care to determine whether it truly “has no place in law under the Constitution” as Chief Justice John Roberts declared in Trump v. Hawaii.1 While Korematsu’s result provides an understandable “impulse to condemn” it, Killenbeck shows us that focusing solely on the case’s result “stands apart from and in stark contrast to its most important place in the constitutional order: articulation of precepts and terminology that provide the foundations for strict scrutiny.

Genomic DNA k-mer spectra: models and modalities

Tetrapods, unlike other organisms, have multimodal spectra of k-mers in their genome

Do We Still Need Experts?

In the wake of the spectacular success of Miranda Fricker's Epistemic Injustice, philosophers have paid a great deal of attention to testimonial injustice. Testimonial injustice occurs when recipients of testimony discount it in virtue of its source: usually, their social identity. The remedy for epistemic injustice is almost always listening better and giving greater weight to the testimony we hear, on most philosophers' implicit or explicit view. But Fricker identifies another kind of epistemic injustice: hermeneutical injustice. This kind of injustice occurs when someone can't articulate their own experience or understand their situation for lack of the hermeneutical tools. There is a possible tension between these kinds of injustice, we suggest: sincere testimony may be misleading (may fail to identify significant harms the testfier is subject, or may fail to register its magnitude, or to categorize it as the kind of harm it is) in virtue of a lack of hermeneutical resources. This tension raises the possibility that there are situations in which experts - those who possess hermeneutical tools - may be able to correct the testimony of those who experience harms in virtue of their identity. In this paper, we identify possible cases in which epistemic injustice might be reduced through such correction: in which an increase in testimonial injustice might serve to decrease it in the longer run, for example. We also suggest how the obvious dangers of a too great readiness to see testimony as in need of expert correction might be mitigated, and how the expert might suggest corrections without ceasing to listen

Completing the FACE of elevated CO₂ research

We appraise the present geographical extent and inherent knowledge limits, following two decades of research on elevated CO2 responses in plant communities, and ask whether such research has answered the key question in quantifying the limits of compensatory CO2 uptake in the major biomes. Our synthesis of all ecosystem-scale (between 10 m2 and 3000 m2 total experimental plot area) elevated CO2 (eCO2) experiments in natural ecosystems conducted worldwide since 1987 (n = 151) demonstrates that the locations of these eCO2 experiments have been spatially biased, targeting primarily the temperate ecosystems of northern America and Europe. We consider the consequences, suggesting fundamentally that this limits the capacity of the research to understand how the world's major plant communities will respond to eCO2. Most notably, our synthesis shows that this research lacks understanding of impacts on tropical forests and boreal regions, which are potentially the most significant biomes for C sink and storage activity, respectively. Using a meta-analysis of the available data across all biomes, we show equivocal increases in net primary productivity (NPP) from eCO2 studies, suggesting that global validation is needed, especially in the most important biomes for C processing. Further, our meta-analysis identifies that few research programs have addressed eCO2 effects on below-ground C storage, such that at the global scale, no overall responses are discernable. Given the disparity highlighted in the distribution of eCO2 experiments globally, we suggest opportunities for newly-industrialized or developing nations to become involved in further research, particularly as these countries host some of the most important regions for tropical or sub-tropical forest systems. Modeling approaches that thus far have attempted to understand the biological response to eCO2 are constrained with respect to collective predictions, suggesting that further work is needed, which will link models to in situ eCO2 experiments, in order to understand how the world's most important regions for terrestrial C uptake and storage will respond to a future eCO2 atmosphere

All-Optical Quantum Random Bit Generation from Intrinsically Binary Phase of Parametric Oscillators

True random number generators (RNGs) are desirable for applications ranging from cryptogra- phy to computer simulations. Quantum phenomena prove to be attractive for physical RNGs due to their fundamental randomness and immunity to attack [1]- [5]. Optical parametric down conversion is an essential element in most quantum optical experiments including optical squeezing [9], and generation of entangled photons [10]. In an optical parametric oscillator (OPO), photons generated through spontaneous down conversion of the pump initiate the oscillation in the absence of other inputs [11, 12]. This quantum process is the dominant effect during the oscillation build-up, leading to selection of one of the two possible phase states above threshold in a degenerate OPO [13]. Building on this, we demonstrate a novel all-optical quantum RNG in which the photodetection is not a part of the random process, and no post processing is required for the generated bit sequence. We implement a synchronously pumped twin degenerate OPO, which comprises two identical independent OPOs in a single cavity, and measure the relative phase states of the OPO outputs above threshold as a bit value. We show that the outcome is statistically random with 99% confidence. With the use of micro- and nanoscale OPO resonators, this technique offers a promise for simple, robust, and high-speed on-chip all-optical quantum random number generators

Challenges in Scaling Up Greenhouse Gas Fluxes: Experience From the UK Greenhouse Gas Emissions and Feedbacks Program

The role of greenhouse gases (GHGs) in global climate change is now well recognized and there is a clear need to measure emissions and verify the efficacy of mitigation measures. To this end, reliable estimates are needed of the GHG balance at the national scale and over long time periods, but these estimates are difficult to make accurately. Because measurement techniques are generally restricted to relatively small spatial and temporal scales, there is a fundamental problem in translating these into long-term estimates on a regional scale. The key challenge lies in spatial and temporal upscaling of short-term, point observations to estimate large-scale annual totals, and quantify the uncertainty associated with this upscaling. Here, we review some approaches to this problem and synthesize the work in the recent UK Greenhouse Gas Emissions and Feedbacks Program, which was designed to identify and address these challenges. Approaches to the scaling problem included: instrumentation developments which mean that near-continuous data sets can be produced with larger spatial coverage; geostatistical methods which address the problem of extrapolating to larger domains, using spatial information in the data; more rigorous statistical methods which characterize the uncertainty in extrapolating to longer time scales; analytical approaches to estimating model aggregation error; enhanced estimates of C flux measurement error; and novel uses of remote sensing data to calibrate process models for generating probabilistic regional C flux estimates

Delusions in frontotemporal lobar degeneration

We assessed the significance and nature of delusions in frontotemporal lobar degeneration (FTLD), an important cause of young-onset dementia with prominent neuropsychiatric features that remain incompletely characterised. The case notes of all patients meeting diagnostic criteria for FTLD attending a tertiary level cognitive disorders clinic over a three year period were retrospectively reviewed and eight patients with a history of delusions were identified. All patients underwent detailed clinical and neuropsychological evaluation and brain MRI. The diagnosis was confirmed pathologically in two cases. The estimated prevalence of delusions was 14 %. Delusions were an early, prominent and persistent feature. They were phenomenologically diverse; however paranoid and somatic delusions were prominent. Behavioural variant FTLD was the most frequently associated clinical subtype and cerebral atrophy was bilateral or predominantly right-sided in most cases. We conclude that delusions may be a clinical issue in FTLD, and this should be explored further in future work

The spread, treatment, and prevention of HIV-1: evolution of a global pandemic

The most up-to-date estimates demonstrate very heterogeneous spread of HIV-1, and more than 30 million people are now living with HIV-1 infection, most of them in sub-Saharan Africa. The efficiency of transmission of HIV-1 depends primarily on the concentration of the virus in the infectious host. Although treatment with antiviral agents has proven a very effective way to improve the health and survival of infected individuals, as we discuss here, the epidemic will continue to grow unless greatly improved prevention strategies can be developed and implemented. No prophylactic vaccine is on the horizon. However, several behavioral and structural strategies have made a difference — male circumcision provides substantial protection from sexually transmitted diseases, including HIV-1, and the application of antiretroviral agents for prevention holds great promise