Trends in mechanical fasteners

Some of the specialty fasteners which are enjoying increasing usage are: thread rolling screws, self drilling and tapping screws, locking screws, tamperproof fasteners, and flanged bolts and nuts. The development of an optimum metric fastener system is recommended for future fastener manufacturing

Triclosan: An Instructive Tale

The Food and Drug Administration (FDA) recently released a final rule to ban triclosan and 18 other antimicrobial chemicals from soaps. We applaud this rule specifically because of the associated risks that triclosan poses to the spread of antibiotic resistance throughout the environment. This persistent chemical constantly stresses bacteria to adapt, and behavior that promotes antibiotic resistance needs to be stopped immediately when the benefits are null

The Growing Importance of Cognitive Skills in Wage Determination

Using data from two longitudinal surveys of American high school seniors, we show that basic cognitive skills had a larger impact on wages for 24-year-old men and women in 1986 than in 1978. For women, the increase in the return to cognitive skills between 1978 and 1986 accounts for all of the increase in the wage premium associated with post-secondary education. We also show that high school seniors' mastery of basic cognitive skills had a much smaller impact on wages two years after graduation than on wages six years after graduation.

Minimizing the effect of sinusoidal trends in detrended fluctuation analysis

The detrended fluctuation analysis (DFA) [Peng et al., 1994] and its extensions (MF-DFA) [Kantelhardt et al., 2002] have been used extensively to determine possible long-range correlations in self-affine signals. While the DFA has been claimed to be a superior technique, recent reports have indicated its susceptibility to trends in the data. In this report, a smoothing filter is proposed to minimize the effect of sinusoidal trends and distortion in the log-log plots obtained by DFA and MF-DFA techniques

Simulation of turbulent transonic separated flow over an airfoil

A code developed for simulating high Reynolds number transonic flow fields of arbitrary configuration is described. This code, in conjunction with laboratory experiments, is used to devise and test turbulence transport models which may be suitable in the prediction of such flow fields, with particular emphasis on regions of flow separation. The solutions describe the flow field, including both the shock-induced and trailing-edge separation regions, in sufficient detail to provide the profile and friction drag

The phase-dependent linear conductance of a superconducting quantum point contact

The exact expression for the phase-dependent linear conductance of a weakly damped superconducting quantum point contact is obtained. The calculation is performed by summing up the complete perturbative series in the coupling between the electrodes. The failure of any finite order perturbative expansion in the limit of small voltage and small quasi-particle damping is analyzed in detail. In the low transmission regime this nonperturbative calculation yields a result which is at variance with standard tunnel theory. Our result predicts the correct sign of the quasi-particle pair interference term and exhibits an unusual phase-dependence at low temperatures in qualitative agreement with the available experimental data.Comment: 12 pages (revtex) + 1 postscript figure. Submitted to Phys. Rev. Let

Scale invariant correlations and the distribution of prime numbers

Negative correlations in the distribution of prime numbers are found to display a scale invariance. This occurs in conjunction with a nonstationary behavior. We compare the prime number series to a type of fractional Brownian motion which incorporates both the scale invariance and the nonstationary behavior. Interesting discrepancies remain. The scale invariance also appears to imply the Riemann hypothesis and we study the use of the former as a test of the latter.Comment: 13 pages, 8 figures, version to appear in J. Phys.

Engineering stochasticity in gene expression

Stochastic fluctuations (noise) in gene expression can cause members of otherwise genetically identical populations to display drastically different phenotypes. An understanding of the sources of noise and the strategies cells employ to function reliably despite noise is proving to be increasingly important in describing the behavior of natural organisms and will be essential for the engineering of synthetic biological systems. Here we describe the design of synthetic constructs, termed ribosome competing RNAs (rcRNAs), as a means to rationally perturb noise in cellular gene expression. We find that noise in gene expression increases in a manner proportional to the ability of an rcRNA to compete for the cellular ribosome pool. We then demonstrate that operons significantly buffer noise between coexpressed genes in a natural cellular background and can even reduce the level of rcRNA enhanced noise. These results demonstrate that synthetic genetic constructs can significantly affect the noise profile of a living cell and, importantly, that operons are a facile genetic strategy for buffering against noise

Hysteresis Switching Loops in Ag-manganite memristive interfaces

Multilevel resistance states in silver-manganite interfaces are studied both experimentally and through a realistic model that includes as a main ingredient the oxygen vacancies diffusion under applied electric fields. The switching threshold and amplitude studied through Hysteresis Switching Loops are found to depend critically on the initial state. The associated vacancy profiles further unveil the prominent role of the effective electric field acting at the interfaces. While experimental results validate main assumptions of the model, the simulations allow to disentangle the microscopic mechanisms behind the resistive switching in metal-transition metal oxide interfaces.Comment: 14 pages, 3 figures, to be published in Jour. of Appl. Phy