Internet-based Multiagent Architecture

Research in intelligent agents and multiagent systems that run on the Internet has received increased attention and importance in recent years. Since the Internet continues to grow, intelligent agent technology is progressively being introduced to many Internet-based applications for communications between different applications. The aim of this paper is to present an Internet-based architecture for multiagent systems which offers a communication infrastructure and coordination services for agents to achieve their goals. A structured architecture is proposed to support communication facilities among several agents and coordinate agent activities in distributed environments such as the Internet and Intranets. The architecture consists of 1) Application agents, 2) Communication handler, 3) Knowledge manager, and 4) Repository. (Yuen, et al. 1999; Leung, et al. 1999). These four layers cooperate together and provide common facilities necessary for typical multiagent systems or agent-based applications with various choices. An Internet-based prototype for auditing and detecting unauthorized transactions within an organization over the Internet or an Intranet is implemented to demonstrate the practicability and feasibility of the proposed Internet-based architecture for multiagent systems

Gao Brothers' Execution of Christ: visual lexicon transcending culture, time, and place

Title from PDF of title page, viewed on May 27, 2011Thesis advisor: Maude WahlmanVitaIncludes bibliographical references (p. 86-91)Thesis (M.A.)--Dept. of Art History. University of Missouri--Kansas City, 2011After the death of Chairman Mao Zedong in 1979, China began a national transformation from a once self-imposed isolated culture to one that hoped to be economically and culturally engaged with the rest of the world. Chinese artists were exposed overwhelmingly to Western contemporary arts and philosophies. With both exposure to new Western artistic concepts and a desire to diverge from traditional Chinese art, which was seen as outdated form of art, Chinese artists wanted to modernize the Chinese arts by creating new visual lexicons and artistic languages. This thesis will discuss how The Gao Brothers were able to apply Western artistic concepts to integrate the Chinese culture and create a unique artistic language while remaining separate from the Western contemporary arts and traditional Chinese arts. The discussion will examine major influences and inspirations that led to the creation of the Gao Brothers' 2009 sculpture, The Execution of Christ, including the artists' family history, occurrences of major historical events, challenges in creating a new identity for a nation, and artistic responses to international influences. Works of the Gao Brothers will be compared and contrasted with other Chinese contemporaries and with Western and Eastern art concepts, philosophies, and techniques. These insights into the Gao Brothers' artistic development process were obtained through criticisms, catalogues, and other published materials, in addition to the author's in-person interviews with The Gao Brothers, their curator, Author Hwang, and the artists' personal art dealer and friend, Melanie Lum. The Gao Brothers are continually evolving the artistic language of their art to reflect changing world. They strive to push cultural and social boundaries to express their feelings of their cultural past as well as hope for the future. The artists are successful in creating avant-garde art by borrowing Western art philosophies and redefining conventional iconographic interpretations within their works, specifically in The Execution of Christ. The combined and redefined uses of art iconography, religious and cultural philosophies in The Execution of Christ, resulted in an artistic language that communicates to all humanity that transcends culture, time, and place.College of Arts and SciencesThe cultural context of Chinese art -- The critical context of understanding The Execution of Christ -- Gao Zhen and Gao Qiang -- The Execution of Christ -- Composition and formal interpretation -- Catharsis and reminder of the human condition -- The Gao brothers and the neo-traditionalists -- Conclusion -- Appendix A. Interview notes and transcripts -- Appendix B. KCUR 89.3 interview transcripts -- Appendix C. Kemper art webcast, part 1 -- Kemper art webcast, part 2 -- PRI, the World: interview transcript -- Appendix G. Melanie Lum interview notesmonographi

Effect of storage temperature on the stability of spray dried bacteriophage powders

This study aimed to assess the robustness of using a spray drying approach and formulation design in producing inhalable phage powders. Two types of Pseudomonas phages, PEV2 (Podovirus) and PEV40 (Myovirus) in two formulations containing different amounts of trehalose (70% and 60%) and leucine (30% and 40%) were studied. Most of the surface of the produced powders was found to be covered in crystalline leucine. The powders were stored at 4 °C and 20 °C under vacuum. The phage stability and in vitro aerosol performance of the phage powders were examined on the day of production and after 1, 3 and 12 months of storage. A minor titer loss during production was observed for both phages (0.2–0.8 log10 pfu/ml). The storage stability of the produced phage powders was found to be phage and formulation dependent. No further reduction in titer occurred for PEV2 powders stored at 4 °C across the study. The formulation containing 30% leucine maintained the viability of PEV2 at 20 °C, while the formulation containing 40% leucine gradually lost titer over time with a storage reduction of ∼0.9 log10 pfu/ml measured after 12 months. In comparison, the PEV40 phage powders generally had a ∼ 0.5 log10 pfu/ml loss upon storage regardless of temperature. When aerosolized, the total in vitro lung doses of PEV2 were of the order of 107 pfu, except the formulation containing 40% leucine stored at 20 °C which had a lower lung dose. The PEV40 powders also had lung doses of 106–107 pfu. The results demonstrate that spray dried Myoviridae and Podoviridae phage in a simple formulation of leucine and trehalose can be successfully stored for one year at 4 °C and 20 °C with vacuum packaging.The University of Sydney; Australian Research Council; National Institute of Allergy and Infectious Diseases of the National Institutes of Health; National Health and Medical Research Council Centre of Research Excellence in Tuberculosis Contro

Top-quark spin correlation at Linear Colliders with anomalous couplings

We investigate the feasibility of probing anomalous top-quark couplings of $Wtb$, $Z t \bar{t}$, and $\gamma t \bar{t}$ in terms of an effective Lagrangian with dimension-six operators at future $e^+e^-$ linear colliders with a c. m. energy $\sqrt s \sim 500-800$ GeV. We first examine the constraints on these anomalous couplings from the $Z\to b \bar{b}$ data at LEP I and from unitarity considerations. We then consider in detail the effects of anomalous couplings on $t \bar{t}$ spin correlations in the top-pair production and decay with three spin bases: the helicity, beamline and off-diagonal bases. Our results show that the polarized beams are more suitable for exploring the effects of different new operators. For polarized beams, the helicity basis yields the best sensitivity.Comment: 23 pages, 10 figures, references adde

Different types of visual cells in the photoreceptor layer of the retinae of the treeshrew (Tupaia belangeri chinensis) as revealed by scanning microscopy

The retinae of treeshrew have never been evaluated by scanning electron microscopic studies. This work described the visual cells in the photoreceptor layer of the retinae of treeshrew (Tupaia belangeri chinensis) living on the high plateau of Yunnan, China, via scanning electron microscopy. Results indicated five different types of cones morphologically, in which two of those have shown oil droplet like structures in their inner segments. To our knowledge, no prior studies have reported oil droplets in the visual cells of higher mammals, only in lower vertebrate and primitive mammals. In addition, this study revealed one type of degenerative visual cell without outer segments. The findings signal the needs for additional studies to understand the physiological functions and phylogenetic relationships of the diversity of visual cells in this group of mammal

Mutations of the BRAF gene in human cancer

Cancers arise owing to the accumulation of mutations in critical genes that alter normal programmes of cell proliferation, differentiation and death. As the first stage of a systematic genome-wide screen for these genes, we have prioritized for analysis signalling pathways in which at least one gene is mutated in human cancer. The RAS RAF MEK ERK MAP kinase pathway mediates cellular responses to growth signals. RAS is mutated to an oncogenic form in about 15% of human cancer. The three RAF genes code for cytoplasmic serine/threonine kinases that are regulated by binding RAS. Here we report BRAF somatic missense mutations in 66% of malignant melanomas and at lower frequency in a wide range of human cancers. All mutations are within the kinase domain, with a single substitution (V599E) accounting for 80%. Mutated BRAF proteins have elevated kinase activity and are transforming in NIH3T3 cells. Furthermore, RAS function is not required for the growth of cancer cell lines with the V599E mutation. As BRAF is a serine/threonine kinase that is commonly activated by somatic point mutation in human cancer, it may provide new therapeutic opportunities in malignant melanoma

Measurement of Cosmic-ray Muon-induced Spallation Neutrons in the Aberdeen Tunnel Underground Laboratory

AbstractMuon-induced neutrons are one of the major backgrounds to various underground experiments, such as dark matter searches, low-energy neutrino oscillation experiments and neutrino-less double beta-decay experiments. Previous experiments on the underground production rate of muon-induced neutrons were mostly carried out either at shallow sites or at very deep sites. The Aberdeen Tunnel experiment aims to measure the neutron production rate at a moderate depth of 611 meters water equivalent. Our apparatus comprises of six layers of plastic-scintillator hodoscopes for tracking the incident cosmic-ray muons, and 760 L of gadolinium-doped liquid-scintillator for both neutron production and detection targets. In this paper, we describe the design and the performance of the apparatus. The preliminary result on the measurement of neutron production rate is also presented

Controversies in spine research: organ culture versus in vivo models for studies of the intervertebral disc

Intervertebral disc degeneration is a common cause of low back pain, the leading cause of disability worldwide. Appropriate preclinical models for intervertebral disc research are essential to achieving a better understanding of underlying pathophysiology and for the development, evaluation, and translation of more effective treatments. To this end, in vivo animal and ex vivo organ culture models are both widely used by spine researchers; however, the relative strengths and weaknesses of these two approaches are a source of ongoing controversy. In this article, members from the Spine and Preclinical Models Sections of the Orthopedic Research Society, including experts in both basic and translational spine research, present contrasting arguments in support of in vivo animal models versus ex vivo organ culture models for studies of the disc, supported by a comprehensive review of the relevant literature. The objective is to provide a deeper understanding of the respective advantages and limitations of these approaches, and advance the field toward a consensus with respect to appropriate model selection and implementation. We conclude that complementary use of several model types and leveraging the unique advantages of each is likely to result in the highest impact research in most instances