A Note on the Flexural Properties of Bark Board

Bending properties of particleboards made from soft maple, red oak, white oak, black cherry, beech, and yellow-poplar bark were obtained and compared with the specimen's density and thickness. Regression analyses indicated that the bending properties depend not only on species but also on density and/or specimen thickness. This dependence was not consistent among species

Lupinosis and rates of stocking of lupin stubbles

Lupin stubbles provide valuable summer sheep feed but under some conditions the fungus Phomopsis rossiana (for which lupins are the host plant) produces a toxin that causes lupinosis. Results from research at Badaingarra Research Station over the 1973-74 and 1974- 75 summers have shown that sheep liver damage associated with lupin stubble grazing is likely to be more severe at high than low stocking rates

Dopamine D_2-receptor activation elicits akinesia, rigidity, catalepsy, and tremor in mice expressing hypersensitive 4 nicotinic receptors via a cholinergic-dependent mechanism

Recent studies suggest that high-affinity neuronal nicotinic acetylcholine receptors (nAChRs) containing α4 and β2 subunits (α4β2*) functionally interact with G-protein-coupled dopamine (DA) D_2 receptors in basal ganglia. We hypothesized that if a functional interaction between these receptors exists, then mice expressing an M2 point mutation (Leu9'Ala) rendering 4 nAChRs hypersensitive to ACh may exhibit altered sensitivity to a D_2-receptor agonist. When challenged with the D_(2)R agonist, quinpirole (0.5–10 mg/kg), Leu9'Ala mice, but not wild-type (WT) littermates, developed severe, reversible motor impairment characterized by rigidity, catalepsy, akinesia, and tremor. While striatal DA tissue content, baseline release, and quinpirole-induced DA depletion did not differ between Leu9'Ala and WT mice, quinpirole dramatically increased activity of cholinergic striatal interneurons only in mutant animals, as measured by increased c-Fos expression in choline acetyltransferase (ChAT)-positive interneurons. Highlighting the importance of the cholinergic system in this mouse model, inhibiting the effects of ACh by blocking muscarinic receptors, or by selectively activating hypersensitive nAChRs with nicotine, rescued motor symptoms. This novel mouse model mimics the imbalance between striatal DA/ACh function associated with severe motor impairment in disorders such as Parkinson’s disease, and the data suggest that a D_(2)R–α4*-nAChR functional interaction regulates cholinergic interneuron activity.—Zhao-Shea, R., Cohen, B. N., Just, H., McClure-Begley, T., Whiteaker, P., Grady, S. R., Salminen, O., Gardner, P. D., Lester, H. A., Tapper, A. R. Dopamine D2-receptor activation elicits akinesia, rigidity, catalepsy, and tremor in mice expressing hypersensitive α4 nicotinic receptors via a cholinergic-dependent mechanism

Simultaneous optical, CUTLASS HF radar, and FAST spacecraft observations: signatures of boundary layer processes in the cusp

International audienceIn this paper we discuss counterstreaming electrons, electric field turbulence, HF radar spectral width enhancements, and field-aligned currents in the southward IMF cusp region. Electric field and particle observations from the FAST spacecraft are compared with CUTLASS Finland spectral width enhancements and ground-based optical data from Svalbard during a meridional crossing of the cusp. The observed 630nm rayed arc (Type-1 cusp aurora) is associated with stepped cusp ion signatures. Simultaneous counterstreaming low-energy electrons on open magnetic field lines lead us to propose that such electrons may be an important source for rayed red arcs through pitch angle scattering in collisions with the upper atmosphere. The observed particle precipitation and electric field turbulence are found to be nearly collocated with the equatorward edge of the optical cusp, in a region where CUTLASS Finland also observed enhanced spectral width. The electric field turbulence is observed to extend far poleward of the optical cusp. The broad-band electric field turbulence corresponds to spatial scale lengths down to 5m. Therefore, we suggest that electric field irregularities are directly responsible for the formation of HF radar backscatter targets and may also explain the observed wide spectra. FAST also encountered two narrow highly structured field-aligned current pairs flowing near the edges of cusp ion steps. Key words. Ionosphere (electric fields and currents). Magnetosphere physics (magnetopause, cusp, and boundary layers; auroral phenomena

An evaluation of metal removal during wastewater treatment: The potential to achieve more stringent final effluent standards

This is the author's accepted manuscript. The final published article is available from the link below. Copyright @ 2011 Taylor & Francis.Metals are of particular importance in relation to water quality, and concern regarding the impact of these contaminants on biodiversity is being encapsulated within the latest water-related legislation such as the Water Framework Directive in Europe and criteria revisions to the Clean Water Act in the United States. This review undertakes an evaluation of the potential of 2-stage wastewater treatment consisting of primary sedimentation and biological treatment in the form of activated sludge processes, to meet more stringent discharge consents that are likely to be introduced as a consequence. The legislation, sources of metals, and mechanisms responsible for their removal are discussed, to elucidate possible pathways by which the performance of conventional processes may be optimized or enhanced. Improvements in effluent quality, achievable by reducing concentrations of suspended solids or biochemical oxygen demand, may also reduce metal concentrations although meeting possible requirements for the removal of copper my be challenging

Dark matter allowed scenarios for Yukawa-unified SO(10) SUSY GUTs

Simple supersymmetric grand unified models based on the gauge group SO(10) require --in addition to gauge and matter unification-- the unification of t-b-\tau Yukawa couplings. Yukawa unification, however, only occurs for very special values of the soft SUSY breaking parameters. We perform a search using a Markov Chain Monte Carlo (MCMC) technique to investigate model parameters and sparticle mass spectra which occur in Yukawa-unified SUSY models, where we also require the relic density of neutralino dark matter to saturate the WMAP-measured abundance. We find the spectrum is characterizd by three mass scales: first/second generation scalars in the multi-TeV range, third generation scalars in the TeV range, and gauginos in the \sim 100 GeV range. Most solutions give far too high a relic abundance of neutralino dark matter. The dark matter discrepancy can be rectified by 1. allowing for neutralino decay to axino plus photon, 2. imposing gaugino mass non-universality or 3. imposing generational non-universality. In addition, the MCMC approach finds 4. a compromise solution where scalar masses are not too heavy, and where neutralino annihilation occurs via the light Higgs h resonance. By imposing weak scale Higgs soft term boundary conditions, we are also able to generate 5. low \mu, m_A solutions with neutralino annihilation via a light A resonance, though these solutions seem to be excluded by CDF/D0 measurements of the B_s\to \mu^+\mu^- branching fraction. Based on the dual requirements of Yukawa coupling unification and dark matter relic density, we predict new physics signals at the LHC from pair production of 350--450 GeV gluinos. The events are characterized by very high b-jet multiplicity and a dilepton mass edge around mz2-mz1 \sim 50-75 GeV.Comment: 35 pages with 21 eps figure

EQUIPT: protocol of a comparative effectiveness research study evaluating cross-context transferability of economic evidence on tobacco control

This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial.This article has been made available through the Brunel Open Access Publishing Fund.Tobacco smoking claims 700 000 lives every year in Europe and the cost of tobacco smoking in the EU is estimated between €98 and €130 billion annually; direct medical care costs and indirect costs such as workday losses each represent half of this amount. Policymakers all across Europe are in need of bespoke information on the economic and wider returns of investing in evidence-based tobacco control, including smoking cessation agendas. EQUIPT is designed to test the transferability of one such economic evidence base-the English Tobacco Return on Investment (ROI) tool-to other EU member states