866 research outputs found

    Time-Scale Domain Characterization of Time-Varying Ultrawideband Infostation Channel

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    The time-scale domain geometrical-based method for the characterization of the time varying ultrawideband (UWB) channel typical of an infostation channel is presented. Compared to methods that use Doppler shift as a measure of time-variation in the channel this model provides a more reliable measure of frequency dispersion caused by terminal mobility in the UWB infostation channel. Particularly, it offers carrier frequency independent method of computing wideband channel responses and parameters which are important for ultrawideband systems. Results show that the frequency dispersion of the channel depends on the frequency and not on the choice of bandwidth. And time dispersion depends on bandwidth and not on the frequency. It is also shown that for time-varying UWB, frame length defined over the coherence time obtained with reference to the carrier frequency results in an error margin which can be reduced by using the coherence time defined with respect to the maximum frequency in a given frequency band. And the estimation of the frequency offset using the time-scale domain (wideband) model presented here (especially in the case of multiband UWB frequency synchronization) is more accurate than using frequency offset estimate obtained from narrowband models

    The Role of Awareness in L2 Development: Theory, Research, and Pedagogy

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    Cognitive psychology and cognitive science appear to agree that attention to stimuli is needed for long-term memory storage and that little, if any, learning can take place without attention. One strand of psycholinguistic research that has drawn quite a lot of interest, both from a theoretical and empirical perspective, is the role awareness plays in second language acquisition (SLA). To promote a further understanding of the role of awareness may potentially contribute to L2 development. This article will (1) briefly describe current theoretical approaches to the role of awareness in language learning, (2) review recent studies that have employed verbal reports to investigate the effects of awareness on L2 development, and (3) provide, based on the review, some awareness-raising pedagogical tasks for the L2 classroom setting

    Patient-Specific Prosthetic Fingers by Remote Collaboration - A Case Study

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    The concealment of amputation through prosthesis usage can shield an amputee from social stigma and help improve the emotional healing process especially at the early stages of hand or finger loss. However, the traditional techniques in prosthesis fabrication defy this as the patients need numerous visits to the clinics for measurements, fitting and follow-ups. This paper presents a method for constructing a prosthetic finger through online collaboration with the designer. The main input from the amputee comes from the Computer Tomography (CT) data in the region of the affected and the non-affected fingers. These data are sent over the internet and the prosthesis is constructed using visualization, computer-aided design and manufacturing tools. The finished product is then shipped to the patient. A case study with a single patient having an amputated ring finger at the proximal interphalangeal joint shows that the proposed method has a potential to address the patient's psychosocial concerns and minimize the exposure of the finger loss to the public.Comment: Open Access articl

    Indoor path loss model for 4G wireless network at 2.6 GHz

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    In this paper, a short-range, narrowband indoor propagation at 2.6 GHz was measured and modeled. The measurement campaign was conducted to characterize the path loss (PL) of Radio frequency (RF) at the Razak School building corridor. The corridor has unique structure and segmented in different sections. The irregular structure of corridor, further with various interior material used gives the unique characterization to the received power. The research work made in this paper is predominately targets to characterizing radio link of 2.6 GHz frequency in typical indoor corridor

    Acoustic wave sparsely activated localization microscopy (AWSALM): super-resolution ultrasound imaging using acoustic activation and deactivation of nanodroplets

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    Photo-activated localization microscopy (PALM) has revolutionized the field of fluorescence microscopy by breaking the diffraction limit in spatial resolution. In this study, “acoustic wave sparsely activated localization microscopy (AWSALM),” an acoustic counterpart of PALM, is developed to super-resolve structures which cannot be resolved by conventional B-mode imaging. AWSALM utilizes acoustic waves to sparsely and stochastically activate decafluorobutane nanodroplets by acoustic vaporization and to simultaneously deactivate the existing vaporized nanodroplets via acoustic destruction. In this method, activation, imaging, and deactivation are all performed using acoustic waves. Experimental results show that sub-wavelength micro-structures not resolvable by standard B-mode ultrasound images can be separated by AWSALM. This technique is flow independent and does not require a low concentration of contrast agents, as is required by current ultrasound super resolution techniques. Acoustic activation and deactivation can be controlled by adjusting the acoustic pressure, which remains well within the FDA approved safety range. In conclusion, this study shows the promise of a flow and contrast agent concentration independent super-resolution ultrasound technique which has potential to be faster and go beyond vascular imaging

    Quantification of vaporized targeted nanodroplets using high-frame-rate ultrasound and optics

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    Owing to their ability to efficiently deliver biological cargo and sense the intracellular milieu, vertical arrays of high aspect ratio nanostructures, known as nanoneedles,are being developed as minimally invasive tools for cell manipulation. However, little is known of the mechanisms of cargo transfer across the cell membrane-nanoneedle interface. Particularly,the contributions of membrane piercing, modulation of membrane permeability and endocytosis to cargo transfer remain largelyunexplored. Here, combining state-of-the-art electron and scanning ion conductance microscopy with molecular biology techniques, we show that porous silicon nanoneedle arrays concurrently stimulate independent endocytic pathways which contribute to enhanced biomolecule delivery into human mesenchymal stem cells. Electron microscopy of the cell membrane at nanoneedle sites shows an intact lipid bilayer, accompanied by an accumulation of clathrin-coated pits and caveolae. Nanoneedles enhance the internalisation of biomolecular markers of endocytosis, highlighting the concurrent activation of caveolae-and clathrin-mediated endocytosis, alongside macropinocytosis. These events contribute to the nanoneedle-mediated delivery (nanoinjection) of nucleic acids into human stem cells, which distribute across the cytosol and the endolysosomal system. This data extends the understanding of how nanoneedles modulate biological processes to mediate interaction with the intracellular space, providing indications for the rational design of improved cell-manipulation technologies

    Individual differences in second language speech learning in classroom settings: roles of awareness in the longitudinal development of Japanese learners’ English /ɹ/ pronunciation

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    The current study longitudinally examined a crucial individual difference variable—i.e., awareness (operationalized as explicit attention and articulatory knowledge)—in adult second language (L2) speech learning in the context of 40 Japanese learners’ English /ɹ/ pronunciation development in an EFL classroom. The participants’ speech, elicited from word reading, sentence reading and timed picture description tasks at the beginning and end of one academic semester, were analyzed in terms of three acoustic dimensions of English /ɹ/—third formant (F3), second formant (F2) and duration. Whereas the participants showed gains in the relatively easy aspect of the English /ɹ/ acquisition (F2 reduction) as a function of increased L2 input, their explicit awareness of accurate English /ɹ/ pronunciation played a significant role in the acquisition of the relatively difficult dimension (lengthening phonemic duration). The awareness-acquisition link was not found, however, for the most difficult dimension (F3 reduction) at least within the timeframe of the project
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