Modification of Altitude Wind Tunnel for Icing and Propulsion Research Study, Part B

This report describes the results of an engineering study conducted for NASA-Lewis Research Center on Modifications to the Altitude Wind Tunnel (AWT) for Icing and Propulsion Research by DSW Engineering Corporation, Orlando, Florida and DSMA International Inc., Toronto, Canada. The engineering study referred to as study 'Part B' has been carried out under authorization of NASA Contract NAS 3-22933 (Ref. 1). The scope of work defined in the Statement of Work 3-169855 (Ref. 2) Revised 2/20/81 was discussed in detail with NASA on October 2, 1981 and covers the following areas: - Fan and Fan Housing. This includes assessment of circuit loss analyses, fan aerodynamics and mechanical conceptual design of variable and fixed pitch fans considering fixed and variable inlet guide vanes. - Fan Drive Systems - considering fixed and variable speed drives with continuous rating of 30,000 HP with overload capability of 45,000. The drive shaft between the motor and fan is to be considered and also the existing foundations for the main drive motor. - 20 ft.Test Section Arrangement - having slotted wall configurations suitable for testing at transonic velocities, with various model support systems required for the anticipated models and tests. A model handling concept aimed for high productivity testing and means for quick access to the model in the test section between test runs. - 45 ft. Test Section - feasible and practical approach for model installation and removal

Investigation of the Damping of Liquids in Right-Circular Cylindrical Tanks, Including the Effects of a Time-Variant Liquid Depth

An experimental investigation was conducted to determine the effects of several basic variables upon the damping of the fundamental antisymmetric mode of liquids in right-circular cylindrical tanks without baffles. The variables examined include liquid depth, efflux rate, liquid amplitude, kinematic viscosity, and tank size. The data are presented in dimensionless form and compared with available theory. For the range of variables examined, variations of efflux rate and liquid amplitude were found to have no significant effects on the liquid damping. The following theoretical relationship was found to be adequate for the prediction of the variation of damping with liquid depth, kinematic viscosity, and tank size: [for equation see full text] where v is the kinematic viscosity, R is the cylinder radius, g is the acceleration due to gravity, and h is the liquid depth. However, the constant K was experimentally found in this investigation to have the value 5.23, which is 50 percent higher than the theoretically predicted value

An Investigation of the Natural Frequencies and Mode Shapes of Liquids in Oblate Spheroidal Tanks

An experimental investigation was conducted to gain some understanding of the character of the free vibration modes of liquids In oblate spheroidal tanks applicable in missile and space vehicle systems, Measured natural frequencies were obtained for the lowest three or four, antisymmetric modes of oscillation as a function of the liquid depth for three orientations of each of several such tanks of different size and oblateness. The orientations considered were such that: (a) the equator of the spheroid was horizontal and oscillations were along a diameter of the circular liquid surface; (b) the equator of the spheroid was vertical and the oscillations were along the minor axis of the elliptical liquid surface; and (c) the equator of the spheroid was vertical and the oscillations were along the major axis of the elliptical liquid surface; The frequency data are presented as dimensionless parameters developed for each orientation to permit the application of the experimental results to the prediction of the natural frequencies of tanks of different size and oblateness. Photographs we re made of representative surface wave or mode, shapes for each orientation

An Experimental Investigation of the Damping of Liquid Oscillations in an Oblate Spheroidal Tank With and Without Baffles

An experimental investigation was conducted to determine the damping of the fundamental antisymmetric mode of oscillation of liquids contained in an oblate spheroidal tank. The decay of the fundamental mode was studied for a range of liquid depths in tanks with and without baffles. In the investigation of baffle effects, ring and cruciform baffles of various sizes were fixed at different locations within the tank. Data presented show the variation of the damping factor with tank fullness and with baffle type, width, location, and orientation as well as the effects of the amplitude of the liquid oscillations and of small variations in the liquid kinematic viscosity on the damping factor. The results of the investigation indicate that the addition of ring baffles to the tank results in an increase in the available effective damping when the baffle plane is in a region near the equilibrium liquid surface, and that cruciform baffles are effective in the damping of the fundamental mode in the near-empty tank. No apparent changes in damping for the tanks having ring baffles were observed as the kinematic viscosity of the liquid was varied over a small range

Mitochondrial DNA phylogeography and population history of the grey wolf Canis lupus

The grey wolf (Canis lupus) and coyote (C. latrans) are highly mobile carnivores that disperse over great distances in search of territories and mates. Previous genetic studies have shown little geographical structure in either species. However, population genetic structure is also influenced by past isolation events and population fluctuations during glacial periods. In this study, control region sequence data from a worldwide sample of grey wolves and a more limited sample of coyotes were analysed. The results suggest that fluctuating population sizes during the late Pleistocene have left a genetic signature on levels of variation in both species. Genealogical measures of nucleotide diversity suggest that historical population sizes were much larger in both species and grey wolves were more numerous than coyotes. Currently, about 300 000 wolves and 7 million coyotes exist. In grey wolves, genetic diversity is greater than that predicted from census population size, reflecting recent historical population declines. By contrast, nucleotide diversity in coyotes is smaller than that predicted by census population size, reflecting a recent population expansion following the extirpation of wolves from much of North America. Both species show little partitioning of haplotypes on continental or regional scales. However, a statistical parsimony analysis indicates local genetic structure that suggests recent restricted gene flow.Peer Reviewe

A genetic record of population isolation in pocket gophers during Holocene climatic change.

ABSTRACT A long-standing question in Quaternary paleontology is whether climate-induced, population-level phenotypic change is a result of large-scale migration or evolution in isolation. To directly measure genetic variation through time, ancient DNA and morphologic variation was measured over 2,400 years in a Holocene sequence of pocket gophers (Thomomys talpoides) from Lamar Cave, Yellowstone National Park, Wyoming. Ancient specimens and modern samples collected near Lamar Cave share mitochondrial cytochrome b sequences that are absent from adjacent localities, suggesting that the population was isolated for the entire period. In contrast, diastemal length, a morphologic character correlated with body size and nutritional level, changed predictably in response to climatic change. Our results demonstrate that small mammal populations can experience the long-term isolation assumed by many theoretical models of microevolutionary change

Combinations of idelalisib with rituximab and/or bendamustine in patients with recurrent indolent non-Hodgkin lymphoma

Key Points Combining phosphatidylinositol-3-kinase δ inhibition with rituximab, bendamustine, or both is feasible and active in relapsed iNHL. The safety of novel combinations should be proven in phase 3 trials before adoption in clinical practice.</jats:p

Participant and workplace champion experiences of an intervention designed to reduce sitting time in desk-based workers : SMART work & life

Background: A cluster randomised controlled trial demonstrated the effectiveness of the SMART Work & Life (SWAL) behaviour change intervention, with and without a height-adjustable desk, for reducing sitting time in desk-based workers. Staff within organisations volunteered to be trained to facilitate delivery of the SWAL intervention and act as workplace champions. This paper presents the experiences of these champions on the training and intervention delivery, and from participants on their intervention participation. Methods: Quantitative and qualitative feedback from workplace champions on their training session was collected. Participants provided quantitative feedback via questionnaires at 3 and 12 month follow-up on the intervention strategies (education, group catch ups, sitting less challenges, self-monitoring and prompts, and the height-adjustable desk [SWAL plus desk group only]). Interviews and focus groups were also conducted at 12 month follow-up with workplace champions and participants respectively to gather more detailed feedback. Transcripts were uploaded to NVivo and the constant comparative approach informed the analysis of the interviews and focus groups. Results: Workplace champions rated the training highly with mean scores ranging from 5.3/6 to 5.7/6 for the eight parts. Most participants felt the education increased their awareness of the health consequences of high levels of sitting (SWAL: 90.7%; SWAL plus desk: 88.2%) and motivated them to change their sitting time (SWAL: 77.5%; SWAL plus desk: 85.77%). A high percentage of participants (70%) reported finding the group catch up session helpful and worthwhile. However, focus groups highlighted mixed responses to the group catch-up sessions, sitting less challenges and self-monitoring intervention components. Participants in the SWAL plus desk group felt that having a height-adjustable desk was key in changing their behaviour, with intrinsic as well as time based factors reported as key influences on the height-adjustable desk usage. In both intervention groups, participants reported a range of benefits from the intervention including more energy, less fatigue, an increase in focus, alertness, productivity and concentration as well as less musculoskeletal problems (SWAL plus desk group only). Work-related, interpersonal, personal attributes, physical office environment and physical barriers were identified as barriers when trying to sit less and move more. Conclusions: Workplace champion and participant feedback on the intervention was largely positive but it is clear that different behaviour change strategies worked for different people indicating that a ‘one size fits all’ approach may not be appropriate for this type of intervention. The SWAL intervention could be tested in a broader range of organisations following a few minor adaptations based on the champion and participant feedback. Trial registration: ISCRCTN registry (ISRCTN11618007)

Physics Laws of Social Science

Economics, and other fields of social science are often criticized as unscientific for their apparent failures to formulate universal laws governing human societies. Whether economics is truly a science is one of the oldest questions. This paper attempts to create such universal laws, and asserts that economics is a branch of quantum physics just like chemistry. Choice is a central concept in economics and other fields of social science, yet there is no corresponding concept of choice in modern physics. This article suggests that by introducing the concept of choice to the existing framework of physics, one can formulate five new physics laws, which establishes a common physics foundation for all fields of social and natural science. Applications in economics, biology, history, and finance prove that these new laws remove the invisible wall, which has been artificially separating social science from natural science. One implication of this article is that to establish a sound scientific foundation for social science requires not only advances in psychology and neurobiology but also a new interpretation of quantum mechanics